Abstract: A method for using a multiplex sensor that provides enhanced selectivity and sensitivity. In this method, one or more parameters of a sample are measured by means of multiple spectroscopic techniques, and interferences from physiological and spectral variables are reduced or eliminated. One or more parameters of the sample are measured by means of at least two spectroscopic techniques, wherein the at least two different spectroscopic techniques are selected from the group consisting of: (a) infrared absorbance (b) scattering (c) emission (d) polarization, and (e) photoacoustics.

Abstract: A multiplex sensor and a method of use that provides enhanced selectivity and sensitivity. In this method, one or more parameters of the sample are measured by means of multiple spectroscopic techniques, and the interferences from physiological and spectral variables are reduced or eliminated. In one embodiment of the present invention comprises a multiplex sensor and a method of use that provides enhanced selectivity and sensitivity. One or more parameters of the sample are measured by means of at least two different spectroscopic techniques, wherein the at least two different spectroscopic techniques are selected from the group consisting of:(a) infrared absorbance(b) scattering(c) emission(d) polarization, and(e) photoacoustics.

Abstract: A noninvasive Raman sensor and an associated method of measuring at least one parameter of a sample, such as the presence or concentration of an analyte. The sensor includes(a) at least one source of light capable of irradiating the sample with substantially monochromatic light;(b) a filtering module for filtering light scattered by the sample, that includes at least one bandpass filter capable of transmitting two different spectral windows; and(c) at least one detector.The method includes(a) irradiating a sample with light from a source of substantially monochromatic light,(b) collecting light that is scattered by the sample,(c) analyzing the scattered light by passing the light through a filtering module that includes at least one bandpass filter that is transmissive for at least two spectral windows, and(d) detecting light that has been filtered by said filtering module.