Abstract: The present disclosure relates to fluidic systems and devices for processing, extracting, or purifying one or more analytes. These systems and devices can be used for processing samples and extracting nucleic acids, for example by isotachophoresis. In particular, the systems and related methods can allow for extraction of nucleic acids, including non-crosslinked nucleic acids, from samples such as tissue or cells. The systems and devices can also be used for multiplex parallel sample processing.

Abstract: A filter frame assembly includes a main frame including a first end and a second end, and a spindle unit disposed at the first end. The spindle unit includes a spindle frame, a dispensing spindle non-rotatably coupled to the spindle frame, and a receiving spindle rotatably coupled to the spindle frame. Each of the dispensing spindle and the receiving spindle is configured to receive a filter web thereon in a wound configuration. The main frame is insertable through a filter slot of an HVAC system from the second end, such that the main frame is at least partially received within the HVAC system and the spindle unit is disposed external to the HVAC system. The filter web extends from the dispensing spindle towards the second end of the main frame and extends back to the receiving spindle, while being at least partially received in the main frame.

Abstract: A method and system of determining a filter life are disclosed. In examples, a method comprises capturing aerosol particles on a filter and measuring absorbance spectra of the aerosol particles captured on the filter. The method further comprises identifying one or more aerosol particle types based on the measured absorbance spectra and determining a mass accumulation of each of the one or more aerosol particle types based on the measured absorbance spectra and the aerosol particle type. The method further comprises determining a median particle size of each of the one or more aerosol particle types based on the measured absorbance spectra and the aerosol particle type and determining a filter life based on the determined mass accumulation and the determined median particle size of each of the one or more aerosol particle types.

Abstract: A method and system of determining air quality are disclosed. In examples, a method comprises identifying one or more aerosol particle types based on an absorbance spectra of aerosol particles captured on a filter and determining a mass concentration of each of the one or more aerosol particle types based on the absorbance spectra and the aerosol particle type. The method further comprises detecting a median particle size of each of the one or more aerosol particle types based on a rate of change of the absorbance spectra and the aerosol particle type. The method further comprises determining an air quality metric based on the identified one or more aerosol particle types, the determined mass concentration of each of the one or more aerosol particle types, and the determined median particle size of each of the one or more aerosol particle types.

Abstract: A framed air filter that includes air filter media and a frame with four frame portions. At least one frame portion includes an inner sidewall and an outer sidewall that meet at a sidewall junction. The sidewall junction extends along a score line that includes at least one cut-scored segment and one crush-scored segment.

Abstract: A framed air filter that includes air filter media and a frame with four frame portions. At least one frame portion includes an inner sidewall and an outer sidewall that meet at a sidewall junction. The sidewall junction extends along a score line that includes at least one cut-scored segment and one crush-scored segment.