Patents by Inventor Michael Leslie Kotewicz

Michael Leslie Kotewicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cloned genes encoding reverse transcriptase lacking RNase H activity
    Patent number: 6610522
    Abstract: The invention relates to a gene which encodes reverse transcriptase having DNA polymerase activity and substantially no RNase H activity. The invention also relates to vectors containing the gene and hosts transformed with the vectors of the invention. The invention also relates to a method of producing reverse transcriptase having DNA polymerase activity and substantially no RNase H activity by expressing the reverse transcriptase genes of the present invention in a host. The invention also relates to a method of producing cDNA from mRNA using the reverse transcriptase of the invention. The invention also relates to a kit for the preparation of cDNA from mRNA comprising the reverse transcriptase of the invention.
    Type: Grant
    Filed: December 24, 1998
    Date of Patent: August 26, 2003
    Assignee: Invitrogen Corporation
    Inventors: Michael Leslie Kotewicz, Gary Floyd Gerard
  • Cloned genes encoding reverse transcriptase lacking RNase H activity
    Patent number: 6589768
    Abstract: The invention relates to a gene which encodes reverse transcriptase having DNA polymerase activity and substantially no RNase H activity. The invention also relates to vectors containing the gene and hosts transformed with the vectors of the invention. The invention also relates to a method of producing reverse transcriptase having DNA polymerase activity and substantially no RNase H activity by expressing the reverse transcriptase genes of the present invention in a host. The invention also relates to a method of producing cDNA from mRNA using the reverse transcriptase of the invention. The invention also relates to a kit for the preparation of cDNA from mRNA comprising the reverse transcriptase of the invention.
    Type: Grant
    Filed: December 24, 1998
    Date of Patent: July 8, 2003
    Assignee: Invitrogen Corporation
    Inventors: Michael Leslie Kotewicz, Gary Floyd Gerard
  • Cloned genes encoding reverse transcriptase lacking RNase H activity
    Publication number: 20030039988
    Abstract: The invention relates to a gene which encodes reverse transcriptase having DNA polymerase activity and substantially no RNase H activity. The invention also relates to vectors containing the gene and hosts transformed with the vectors of the invention. The invention also relates to a method of producing reverse transcriptase having DNA polymerase activity and substantially no RNase H activity by expressing the reverse transcriptase genes of the present invention in a host. The invention also relates to a method of producing cDNA from mRNA using the reverse transcriptase of the invention. The invention also relates to a kit for the preparation of cDNA from mRNA comprising the reverse transcriptase of the invention.
    Type: Application
    Filed: December 21, 2001
    Publication date: February 27, 2003
    Inventors: Michael Leslie Kotewicz, Gary Floyd Gerard
  • Cloned genes encoding reverse transcriptase lacking RNase H activity
    Publication number: 20030027313
    Abstract: The invention relates to a gene which encodes reverse transcriptase having DNA polymerase activity and substantially no RNase H activity. The invention also relates to vectors containing the gene and hosts transformed with the vectors of the invention. The invention also relates to a method of producing reverse transcriptase having DNA polymerase activity and substantially no RNase H activity by expressing the reverse transcriptase genes of the present invention in a host. The invention also relates to a method of producing cDNA from mRNA using the reverse transcriptase of the invention. The invention also relates to a kit for the preparation of cDNA from mRNA comprising the reverse transcriptase of the invention.
    Type: Application
    Filed: December 21, 2001
    Publication date: February 6, 2003
    Inventors: Michael Leslie Kotewicz, Gary Floyd Gerard
  • Cloned genes encoding reverse transcriptase lacking RNase H activity
    Patent number: 6063608
    Abstract: The invention relates to a gene which encodes reverse transcriptase having DNA polymerase activity and substantially no RNase H activity. The invention also relates to vectors containing the gene and hosts transformed with the vectors of the invention. The invention also relates to a method of producing reverse transcriptase having DNA polymerase activity and substantially no RNase H activity by expressing the reverse transcriptase genes of the present invention in a host. The invention also relates to a method of producing cDNA from mRNA using the reverse transcriptase of the invention. The invention also relates to a kit for the preparation of cDNA from mRNA comprising the reverse transcriptase of the invention.
    Type: Grant
    Filed: February 10, 1997
    Date of Patent: May 16, 2000
    Assignee: Life Technologies, Inc.
    Inventors: Michael Leslie Kotewicz, Gary Floyd Gerard
  • Cloned genes encoding reverse transcriptase lacking RNASE H activity
    Patent number: 5668005
    Abstract: The invention relates to a gene which encodes reverse transcriptase having DNA polymerase activity and substantially no RNase H activity. The invention also relates to vectors containing the gene and hosts transformed with the vectors of the invention. The invention also relates to a method of producing reverse transcriptase having DNA polymerase activity and substantially no RNase H activity by expressing the reverse transcriptase genes of the present invention in a host. The invention also relates to a method of producing cDNA from mRNA using the reverse transcriptase of the invention. The invention also relates to a kit for the preparation of cDNA from mRNA comprising the reverse transcriptase of the invention.
    Type: Grant
    Filed: March 12, 1996
    Date of Patent: September 16, 1997
    Assignee: Life Technologies, Inc.
    Inventors: Michael Leslie Kotewicz, Gary Floyd Gerard