Abstract: A display may have a pixel array such as a liquid crystal pixel array. The pixel array may be illuminated with backlight illumination from a direct-lit backlight unit. The backlight unit may include an array of light-emitting diodes (LEDs) on a printed circuit board. The display may have a notch to accommodate an input-output component. Reflective layers may be included in the notch. The backlight may include a color conversion layer with a property that varies as a function of position. The light-emitting diodes may be covered by a slab of encapsulant with recesses in an upper surface.

Abstract: The invention provides a novel class of therapeutic agents that are safe and effective TYK2 inhibitors and pharmaceutical compositions of these compounds and methods of preparation and use thereof against various TYK2-mediated diseases and disorders.

Abstract: The disclosed computer-implemented method may include systems for generating personalized avatar reactions during live video broadcasts. For example, the systems and methods described herein can access a social networking system user's profile to identify an avatar associated with the social networking system user. The systems and methods can generate an avatar reaction by modifying one or more features of the avatar based on a corresponding emoticon reaction. Once generated, the social networking system user can select the avatar reaction for addition to an ephemeral reaction stream associated with a live video broadcast. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: Virus and microbe-killing, self-sterilizing resistive heated air filters and methods of making and using same methods. The air filter is includes laser-induced graphene (LIG), a porous conductive graphene foam formed through photothermal conversion of a polyimide film (or another source or source of polymer or other LIG precursor material) by a laser source. The LIG in the air filter can capture particulates and bacteria. The bacteria cannot proliferate even when submerged in culture medium. Through a periodic Joule-heating mechanism, the filter easily reaches greater than 300° C. This destroys any microorganisms including bacteria, along with molecules that can cause adverse biological reactions and diseases such as viruses, pyrogens, allergens, exotoxins, endotoxins, teichoic acids, mycotoxins, nucleic acids, and prions.

Abstract: A component and a system for mitigating coke formation during delivery of a hydrocarbon fluid. The component includes a contact surface configured to be in contact with the hydrocarbon fluid. Tuning the zeta potential of the contact surface allows selective attraction and/or repulsion of coke-catalyzing materials, metal ions, heteroatomic hydrocarbons, and/or coke precursors present in the hydrocarbon fluid. A method of mitigating coke formation during delivery of a hydrocarbon fluid includes tuning a zeta potential of the contact surface of the component and injecting or circulating the hydrocarbon fluid through the system such that the contact surface selectively attracts and/or repels coke-catalyzing materials, metal ions, heteroatomic hydrocarbons, and/or coke precursors present in the hydrocarbon fluid.

Abstract: A distributed imaging system for augmented reality devices is disclosed. The system includes a computing module in communication with a plurality of spatially distributed sensing devices. The computing module is configured to process input images from the sensing devices based on performing a local feature matching computation to generate corresponding first output images. The computing module is further configured to process the input images based on performing an optical flow correspondence computation to generate corresponding second output images. The computing module is further configured to computationally combine first and second output images to generate third output images.

Abstract: Radio networks such as Public Land Mobile Networks (PLMNs), user equipment devices (UEs), servers such as Internet-of-Things servers, and core network entities may be adapted to facilitate transfers of connections of wireless devices. For example, a first PLMN may provide restricted access to a UE to assist the UE in finding a second PLMN for a full connection. Entities may be adapted to support for non-coverage related PLMN transfers, such as transfers initiated by UEs, PLMNs, servers, and core network entities, e.g., in response to changing usage, congestion, etc.

Abstract: The application is at least directed to a core network including a non-transitory memory having instructions stored thereon for registering a network function or network function template in the core network. The network includes a processor, operably coupled to the non-transitory memory. The processor is configured to perform the instruction of determining that registration of the network function or network function template is acceptable. The processor is also configured to perform the instruction of transmitting a message including the network function or network function template to a repository in the core network. The processor is also configured to perform the instruction of verifying the network function or network function template against existing policies in the core network. The processor is also configured to perform the instruction of registering the network function or network function template in the repository after verification.

Abstract: Various embodiments of a dural elevating and cutting apparatus and methods of use are disclosed herein.

Abstract: System and methods that improve the use of network functions on edge data networks are disclosed. A mechanism that supports edge-assisted UE context and trigger collection is described herein, where a UE can actively send its context information and/or any trigger (e.g. a request for a network function/service to be deployed in edge data networks, etc.) to an edge enabler server, which processes the received context and triggers from its UEs. The edge enabler server may also forward UE context and triggers to 5G core network (5GC) upon receiving a solicitation request from the 5GC, or if the 5GC has already made a subscription for getting notification on UE context and triggers. A network repository function is provided as a new network function collect, store, and manage edge data network information.

Abstract: In some embodiments, a method for processing an optical fiber includes: drawing an optical fiber through a draw furnace, conveying the optical fiber through a flame reheating device downstream from the draw furnace, wherein the flame reheating device comprises one or more burners each comprising: a body having a top surface and an opposing bottom surface, an opening within the body extending from the top surface through the body to the bottom surface, wherein the optical fiber passes through the opening, and one or more gas outlets within the body; and igniting a flammable gas provided by the one or more gas outlets to form a flame encircling the optical fiber passing through the opening, wherein the flame heats the optical fiber by at least 100 degrees Celsius at a heating rate exceeding 10,000 degrees Celsius/second.

Abstract: A push gateway brokers messages between backend services and client devices connected to the gateway. The gateway includes a plurality of messaging frontend servers, a messaging database, and a plurality of topic servers. The messaging frontend servers manage the socket connections connecting the client devices to the push gateway. The messaging frontend servers may further monitor the socket connections, collecting analytical data on the client devices and the connections. The messaging database is a key-value database that subscribes messaging frontend servers to topics. The topic servers receive publish requests from the backend servers to identify subscribed messaging frontend servers in the messaging database to push messages out to. The frontend messaging servers subsequently push out the message to the client devices subscribed to the topic.

Abstract: A method of controlling a vibrational transducer, the method comprising: tracking a temperature metric of the vibrational transducer; and controlling a drive signal for the vibrational transducer, where the drive signal is limited to a value to protect the vibrational transducer from over excursion, and where said value is a function of the tracked temperature metric.

Abstract: A system and method for adaptive illumination, the imaging system comprising an excitation source having a modulator, which generates a pulse intensity pattern having a first wavelength when the excitation source receives a modulation pattern. The modulation pattern is a data sequence of a structural image of a sample. An amplifier of the imaging system is configured to receive and amplify the pulse intensity pattern from the modulator. A frequency shift mechanism of the imaging system shifts the first wavelength of the pulse intensity pattern to a second wavelength. A laser scanning microscope of the imaging system receives the pulse intensity pattern having the second wavelength.

Abstract: A method of processing an anisotropic permanent magnet includes forming anisotropic flakes from a hulk magnet alloy, each of the anisotropic flakes having an easy magnetization direction with respect to a surface of the flake and combining the anisotropic flakes with a binder to form a mixture. The method further includes extruding or rolling the mixture without applying a magnetic field such that the easy magnetization directions of the anisotropic flakes align to form one or more layers having a magnetization direction aligned with the easy magnetization directions of the anisotropic flakes, and producing the anisotropic permanent magnet from the layers having the magnetization direction such that the anisotropic permanent magnet has a magnetization with a specific orientation.

Abstract: An antibody that specifically binds to IL-1R3, comprising an antibody heavy chain amino acid sequence of SEQ ID NO: 1 and a light chain amino acid sequence of SEQ ID NO: 2. A pharmaceutical composition is provided comprising the said antibody and a pharmaceutically acceptable diluent, carrier or excipient. Also said antibody for use in treating a disease or disorder in a subject in need thereof. The disease or disorder may be an autoimmune or autoinflammatory disease or disorder.

Abstract: A device (15) including a piezoelectric sensor (16). The piezoelectric sensor (16) includes a layer of piezoelectric material (7) disposed between a number of sensing electrodes (4, 12, 13) and at least one counter electrode (3). The device (15) also includes a controller (17) connected to the piezoelectric sensor (16). The sensing electrodes (4, 12, 13) are arranged to form one or more active regions (19). Each active region (19) includes one or more primary sensing electrodes (4,12) and one or more secondary sensing electrodes (4, 13). The secondary sensing electrodes (4, 13) are separated from the primary sensing electrodes (4, 12) by a perimeter (14). The controller (17) is configured, for each active region (19), to monitor primary piezoelectric charges induced on each primary sensing electrode (4, 12) and to monitor secondary piezoelectric charges induced on each secondary sensing electrode (4, 13).

Abstract: The present invention provides a method of treating heart failure with reduced ejection fraction, by administering to a patient at risk of such damage, a pharmaceutically effective amount of a composition which inhibits the anchoring of PP2A to mAKAP?. This composition is preferably in the form of a viral based gene therapy vector that encodes a fragment of mAKAP? to which PP2A binds.

Abstract: Compositions and methods are provided for stacking multiple independent transgenic loci into the genome of a plant. Compositions include plants, seeds or plant cells comprising at least one transgenic target site and at least one genomic locus of interest integrated at different genomic sites within a genomic window. Plant breeding techniques can be employed such that the transgenic target site and the genomic locus of interest can be bred together. In this way, multiple independent transgene integrations can be generated within a genomic window to create a complex trait locus. The complex trait locus is designed such that the transgenic target sites and/or genomic loci of interest can segregate independently of each other, thus providing the benefit of altering a complex trait locus by breeding-in and breeding-away specific elements. Various methods can also be employed to modify the target sites such that they contain a variety of polynucleotides of interest.

Abstract: The invention relates to novel benzodiazepine derivatives with antiproliferative activity and more specifically to novel benzodiazepine compounds of formula (I)-(VII). The invention also provides conjugates of the benzodiazepine compounds linked to a cell-binding agent. The invention further provides compositions and methods useful for inhibiting abnormal cell growth or treating a proliferative disorder in a mammal using the compounds or conjugates of the invention.