Abstract: The invention relates to the storage of information in nucleic acid sequences. The invention also relates to nucleic acid sequences containing desired information and to the design, production or use of sequences of this type.

Abstract: A lid for covering a container has a lid body having a peripheral connection for connecting to the container, a first hole in the lid body, the first body having a first shape, a second hole in the lid body, the second hole having a second shape that is different from the first shape, and a slidable cover member that slides in a groove formed in the lid body between a covered position and an uncovered position to selectively cover and uncover the first hole. The lid includes a pivoting plug that pivots in a space between the ramps between a plugged position and an unplugged position to selectively plug the second hole.

Abstract: The disclosure generally relates to compositions and methods for the enzymatic synthesis of nucleic acid sequences. In particular embodiments 3? protected nucleotides are used in conjunction with a universal template to direct synthesis.

Abstract: The present disclosure generally relates to compositions, methods and kits for sorting and assembly of nucleic acid molecules, such as synthetic single-stranded oligonucleotides into larger nucleic acid molecules by mixing said single-stranded oligonucleotides with a linear double-stranded vector. The disclosed compositions and methods allow for miniaturization, parallelization, high throughput production and cost reduction of nucleic acid assembly and gene synthesis.

Abstract: The disclosure generally relates to compositions and methods for the enzymatic synthesis of nucleic acid sequences. In particular embodiments 3? protected nucleotides are used in conjunction with a universal template to direct synthesis.

Abstract: The present invention relates to the storage of information in nucleic acid sequences. The invention also relates to nucleic acid sequences containing desired information and to the design, production or use of sequences of this type.

Abstract: The present invention relates to a method for identifying frameshift mutations in coding nucleic acid sequences.

Abstract: The present invention relates to the storage of items of information in nucleic acid sequences. The invention also relates to nucleic acid sequences in which desired items of information are contained, and to the design, production or use of such sequences.

Abstract: The present invention relates to reading-frame-correct fragment libraries, methods for their production, and the use of the fragment libraries for selection of functional polypeptide variants with improved properties.

Abstract: The invention relates to the storage of information in nucleic acid sequences. The invention also relates to nucleic acid sequences containing desired information and to the design, production or use of sequences of this type.

Abstract: The present invention relates to a method for identifying frameshift mutations in coding nucleic acid sequences.

Abstract: The present invention relates to methods for producing variants of proteins which have improved properties in comparison with the initial protein, the variants being obtained with the aid of an in vivo evolution method.

Abstract: The present invention relates to the production of variants of a protein in an in vitro evolution method, comprising the steps: (A) provision of an in vitro expression system comprising (i) a nucleic acid sequence S which codes for a protein Y which is to be varied, (ii) a target molecule X which is able to bind to the protein Y and/or at least one variant Y? thereof, (iii) an RNA polymerase (Pol) which is able to transcribe the nucleic acid sequence S, (iv) a reverse transcriptase (RT) which is capable of reverse transcription of transcripts of the nucleic acid sequence S, where either the target molecule X is coupled to Pol and the protein Y is coupled to RT, or the target molecule X is coupled to RT and the protein Y is coupled to Pol, (B)incubation of the in vitro expression system from (A) under conditions which enable transcription, reverse transcription and translation to form variants Y? of the protein Y and nucleic acid sequences S? coding therefor, and which favor the formation of variants Y? with i