Abstract: A system and method for providing a user of communications services with free market based pricing may include providing for communications over one of multiple network paths serviced by multiple respective communications service providers via at least one communications network. One of the network paths over which to communicate based on current pricing from the multiple communications service providers may be selected and communications may be performed over the selected network path.

Abstract: The invention includes, in part, a method of selecting a subject having cancer for treatment with a JAK/STAT inhibitor and a method of determining if a therapeutically effective dose of a JAK/STAT inhibitor has been administered.

Abstract: The disclosed embodiments include a system and method for establishing a price for communicating over a communications network. In one embodiment, the system includes a plurality of network nodes configured to communicate over the communications network and a primary network edge node configured to provide network access to a plurality of end user devices. The primary network edge node is configured to initiate a bandwidth occupancy query message to at least one of said network nodes along a traffic path to which an end user device is communicating, determine a highest bandwidth occupancy of said network nodes along the traffic path, and compute a current price for the end user device communicating over the traffic path based on the highest bandwidth occupancy.

Abstract: A system and method for providing a user of communications services with free market based pricing may include providing for communications over one of multiple network paths serviced by multiple respective communications service providers via at least one communications network. One of the network paths over which to communicate based on current pricing from the multiple communications service providers may be selected and communications may be performed over the selected network path.

Abstract: In one embodiment of the present invention, a system and method may be provided for validating communications permissions for an in progress communication. The system and method may include receiving location information, at a service provider, from a wireless communications device. The location information may be communicated to a database that is able to determine communications permissions based upon some predetermined criteria, such as time, date, and location. Based upon the received location information and a related database record, permissions for the wireless communications device may be determined. The determined permissions may be communicated to the service provider. The wireless communications device may be notified about restrictions on its communications, in response to receiving the permissions. The permissions determination may be repeated, as necessary, in response to receiving updated location information.

Abstract: In one embodiment of the present invention, a system and method may be provided for validating communications permissions for an in progress communication. The system and method may include receiving location information, at a service provider, from a wireless communications device. The location information may be communicated to a database that is able to determine communications permissions based upon some predetermined criteria, such as time, date, and location. Based upon the received location information and a related database record, permissions for the wireless communications device may be determined. The determined permissions may be communicated to the service provider. The wireless communications device may be notified about restrictions on its communications, in response to receiving the permissions. The permissions determination may be repeated, as necessary, in response to receiving updated location information.

Abstract: The disclosed embodiments include a method, apparatus, and computer program product for restricting communications at a network level. For example, one disclosed embodiment includes a system that includes at least one processor and at least one memory coupled to the at least one processor. The memory stores instructions that when executed by the at least one processor performs operations that includes receiving location coordinates such as, but not limited to, a building's coordinates, a name of a business, and a freeform shape that defines a boundary. The operations include restricting, at the network level, communications associated with a device determined to be within a boundary corresponding to the location coordinates.

Abstract: In one embodiment of the present invention, a system and method may be provided for validating communication for a wireless communications device. The system and method may include receiving a geographic location of a wireless communications device. A database comprising records correlating the geographic location with permissions may be accessed in order to determine, based upon the received geographic location information and the accessed database record, if there are restriction on communication associated with the wireless communications device. An indicator may be communicated in response to the determined restriction, effectively providing the information needed to inform the wireless communications device of any current restrictions.

Abstract: Embodiments of a method, system, and apparatus for inserting caller identifying information into a video signal includes receiving a digital video stream and receiving caller identifier information from an incoming call associated with a calling device. The method further includes converting the caller identifier information into caller identifying textual information, and inserting the caller identifying textual information into the digital video stream using a visual timecode video insertion format. The method further includes transmitting the digital video stream with the inserted caller identifying textual information.

Abstract: A system and method for managing customer premise equipment (CPE) devices. A wake signal is issued to the CPE device. Action parameters are communicated to the CPE device in response to receiving acknowledgement of the wake signal from the CPE device. A management session is established with the CPE device utilizing an address for secure communications in response to the CPE device acknowledging the action parameters. Communications are performed through the management session to perform operation, administration, and maintenance of the CPE device. The management session with the CPE device is terminated.

Abstract: A system and method for managing customer premise equipment (CPE) devices. A wake signal is issued to the CPE device. Action parameters are communicated to the CPE device in response to receiving acknowledgement of the wake signal from the CPE device. A management session is established with the CPE device utilizing an address for secure communications in response to the CPE device acknowledging the action parameters. Communications are performed through the management session to perform operation, administration, and maintenance of the CPE device. The management session with the CPE device is terminated.

Abstract: TGR5 agonists of structural formula VIII(Q), wherein X, R1, R2, and R5 are defined in the specification, pharmaceutically acceptable salts thereof, compositions thereof, and use of the compounds and compositions for treating diseases. The invention also comprises use of the compounds in and for the manufacture of medicaments, particularly for treating diseases.

Abstract: A microelectronic circuit having at least one component adjacent a carrier which is not a semiconductor or sapphire.

Abstract: The present invention comprises TGR5 agonists of structural formula I, wherein X, R1, R2, and R5 are defined herein, as well as N-oxides of them and pharmaceutically acceptable salts thereof. The invention further comprises composition comprising the compounds, N-oxides, and/or pharmaceutically acceptable salts thereof. The invention also comprises use of the compounds and compositions for treating diseases in which TGR5 is a mediator or is implicated. The invention also comprises use of the compounds in and for the manufacture of medicaments, particularly for treating diseases in which TGR5 is a mediator or is implicated.

Abstract: In one embodiment of the present invention, a system and method may be provided for validating communication for a wireless communications device. The system and method may include receiving a geographic location of a wireless communications device. A database comprising records correlating the geographic location with permissions may be accessed in order to determine, based upon the received geographic location information and the accessed database record, if there are restriction on communication associated with the wireless communications device. An indicator may be communicated in response to the determined restriction, effectively providing the information needed to inform the wireless communications device of any current restrictions.

Abstract: In one embodiment of the present invention, a system and method may be provided for validating communications permissions for an in progress communication. The system and method may include receiving location information, at a service provider, from a wireless communications device. The location information may be communicated to a database that is able to determine communications permissions based upon some predetermined criteria, such as time, date, and location. Based upon the received location information and a related database record, permissions for the wireless communications device may be determined. The determined permissions may be communicated to the service provider. The wireless communications device may be notified about restrictions on its communications, in response to receiving the permissions. The permissions determination may be repeated, as necessary, in response to receiving updated location information.

Abstract: A method for link layer address proxying includes receiving a first data packet from a first client device. The first data packet has a first source data link layer address field and a first source network layer address field. The method further includes determining a first data link layer address value associated with the first client device from the first source data link layer address field. The method further includes determining a first network layer address value associated with the first client device from the first source network layer address field, and translating the first data link layer address value into a proxy data link layer address value assigned to the first client device. The method still further includes replacing the first data link layer address value within the first source data link layer address field with the proxy data link layer address value to produce a first proxied data packet, and forwarding the first proxied data packet to a destination device.

Abstract: A method and apparatus are disclosed for distributing content items to a handheld device using a personal computer. A user can browse and select content using a personal computer or other computer that may be more readily available or more convenient to use than the handheld device. The personal computer can communicate with a web server which receives the user's request for content to be distributed to the handheld device. The web server can retrieve configuration information pertaining to the handheld device and communicate with a content server to determine whether the user's request for content distribution is valid based on information identifying the handheld device and at least some of the configuration information pertaining to the handheld device. The content server can transmit the requested content item to the handheld device if the user's request is valid and if the handheld device is able to receive the content item.

Abstract: In one embodiment of the present invention, a system and method may be provided for validating communication for a wireless communications device. The system and method may include receiving a geographic location of a wireless communications device. A database comprising records correlating the geographic location with permissions may be accessed in order to determine, based upon the received geographic location information and the accessed database record, if there are restriction on communication associated with the wireless communications device. An indicator may be communicated in response to the determined restriction, effectively providing the information needed to inform the wireless communications device of any current restrictions.

Abstract: A computer system includes a database module, a query module, a translation module, a search module, and a transmission module. The database module is configured to receive and store information associated with a plurality of items of digital media, such as applications, in a database. The information associated with the plurality of items of digital media is stored in a first language. The query module is configured to receive a search request in a second language different than the first language. The translation module is configured to translate the search request from the second language into the first language. The search module is configured to search the database using the translated search request to produce a set of search results responsive to the search request. The transmission module is configured to transmit the set of search results.