Abstract: A method of mixing a pharmaceutical solution including adding a gas into an interior compartment of a mix bag to form a headspace. The interior compartment of the mix bag includes a top portion and a bottom portion. The headspace adjacent to the top portion contains gas. The method includes adding a solvent into the mix bag, and establishing a bubble column in the interior compartment by activating a recirculation assembly. The recirculation assembly includes a connecting pathway operably coupled to a recirculation pump. A first end of the connecting pathway is coupled to a top gas recirculation port and a second end is coupled to a bottom gas recirculation port of the mix bag such that the recirculation pump draws the gas from the headspace and delivers the gas to the interior compartment via the bottom gas recirculation port. The method includes adding a solute into the mix bag.

Abstract: A method of mixing a pharmaceutical solution including adding a gas into an interior compartment of a mix bag to form a headspace. The interior compartment of the mix bag includes a top portion and a bottom portion. The headspace adjacent to the top portion contains gas. The method includes adding a solvent into the mix bag, and establishing a bubble column in the interior compartment by activating a recirculation assembly. The recirculation assembly includes a connecting pathway operably coupled to a recirculation pump. A first end of the connecting pathway is coupled to a top gas recirculation port and a second end is coupled to a bottom gas recirculation port of the mix bag such that the recirculation pump draws the gas from the headspace and delivers the gas to the interior compartment via the bottom gas recirculation port. The method includes adding a solute into the mix bag.

Abstract: A storage tray for one or more syringes includes a recess for each of the syringes to be held in the tray. Each recess has first and second opposed sidewalls that define a space therebetween for receiving the barrel of the syringe. Each of the first and second sidewalls has one or more deformable projections thereon that protrude into the space between the sidewalls for positively retaining the barrel of the syringe between the first and second sidewalls. Additionally, a slot is provided for receiving the thumb rest of the plunger. The slot includes a third sidewall oriented generally transverse to the first and second sidewalls, with the third sidewall including a further projection for engaging a surface of the thumb rest. Preferably, a plurality of such transverse slots is provided to accommodate different positions of the plunger relative to the syringe barrel.

Abstract: A storage system is provided. The system may include a tray having at least one recess in which at least one syringe is disposed, the syringe including a barrel with first and second barrel ends, and a stopper fixedly disposed between the first and second barrel ends. A tool attached to the stopper through the second barrel end, the tool having a first end attached to the stopper and a second end attached to or abutting the barrel or a surface of the recess, the first end being selectively adjustable relative to the second end to vary the distance between the first and second ends of the tool. In addition or in the alternative to the tool, the system may include a motion generator attached externally to the syringe, the motion generator being one of at least a vibration generator and a rotating frame.

Abstract: A storage tray (10) for one or more syringes is provided that comprises a recess (32) for each of the syringes to be held in the tray. Each recess has first and second opposed sidewalls (34, 36) that define a space therebetween for receiving the barrel of the syringe. Each of the first and second sidewalls has one or more deformable projections (40) thereon that protrude into the space between the sidewalls for positively retaining the barrel of the syringe between the first and second sidewalls. Additionally, a slot (50) is provided for receiving the thumb rest (16) of the plunger (14), with the slot comprising a third sidewall (52) oriented generally transverse to the first and second sidewalls, with the third sidewall including a further projection (54) for engaging a surface of the thumb rest.

Abstract: A storage system is provided. The system may include a tray having at least one recess in which at least one syringe is disposed, the syringe including a barrel with first and second barrel ends, and a stopper fixedly disposed between the first and second barrel ends. A tool attached to the stopper through the second barrel end, the tool having a first end attached to the stopper and a second end attached to or abutting the barrel or a surface of the recess, the first end being selectively adjustable relative to the second end to vary the distance between the first and second ends of the tool. In addition or in the alternative to the tool, the system may include a motion generator attached externally to the syringe, the motion generator being one of at least a vibration generator and a rotating frame.