Abstract: Disclosed herein are methods for forecasting response to lupus nephritis (LN) therapy in individual diagnosed with childhood-onset SLE (cSLE). The methods may include the step of detecting each protein in a protein set in a sample obtained from an individual in need thereof. The protein set may include ceruloplasmin, kidney injury molecule 1 (KIM-1), monocyte chemotactic protein 1 (MCP-1), adiponectin, hemopexin, and NGAL.

Abstract: Disclosed are methods for the identification of an individual likely to have steroid resistant nephrotic syndrome (SRNS). The disclosed methods may include detection a plurality of proteins. The plurality of proteins may include, for example, Vitamin D Binding Protein (VDBP), Alpha-1 Acid Glycoprotein 2 (AGP-2), Fetuin A, prealbumin, and NGAL in a urine sample obtained from said individual. The methods may further include detection of Alpha-1 Acid Glycoprotein 1 (AGP-1), Alpha-1 B Glycoprotein (A1BG), Thyroxine binding globulin, hemopexin, and alpha-2 macroglobulin.

Abstract: Disclosed are methods of determining whether a patient diagnosed with nephrotic syndrome has steroid sensitive nephrotic syndrome (SSNS) or steroid resistant nephrotic syndrome (SRNS) by determining the levels of one or more biomarkers in a biofluid from the patient. Also disclosed are methods of treating a patient diagnosed with nephrotic syndrome, and kits and substrates related to the disclosed methods.

Abstract: Disclosed are methods of determining whether a patient diagnosed with nephrotic syndrome has steroid sensitive nephrotic syndrome (SSNS) or steroid resistant nephrotic syndrome (SRNS) by determining the levels of one or more biomarkers in a biofluid from the patient. Also disclosed are methods of treating a patient diagnosed with nephrotic syndrome, and kits and substrates related to the disclosed methods.

Abstract: A method and apparatus for calibrating the air flow in a respirator system is provided. The method provides for the establishment of control set points in a true calibration protocol through the simple triggering of the microprocessor of a controller. When the trigger is initiated, the microprocessor engages and provides the logic for the calibration cycle. The calibration cycle proceeds until a second trigger terminates the process and establishes the control set points. The calibration sequence of the method relies only on an initiation and termination trigger that is facilitated by components integral to the apparatus.