Patents by Inventor Michael R. Hoffmann

Michael R. Hoffmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11760662
    Abstract: Aspects of the invention include a porous and water-permeable electrode for electrocatalysis comprising: a porous and water-permeable reactive electrochemical membrane (“REM”) comprising: a porous and water-permeable support membrane; wherein the support membrane comprises a titanium metal; and an electrocatalytic coating on at least a portion of the metal support membrane, the electrocatalytic coating being a tin oxide bilayer comprising: a first layer adjacent to and directly contacting the metal support membrane; wherein the first layer comprises tin oxide doped with antimony; and a second layer adjacent to and directly contacting the first layer; wherein the second layer forms a surface of the REM such that the second layer is in direct contact with an aqueous solution when the REM is in contact with the aqueous solution; wherein the second layer comprises tin oxide doped with antimony and nickel or cerium. Preferably, the support membrane is formed of a titanium metal.
    Type: Grant
    Filed: June 25, 2020
    Date of Patent: September 19, 2023
    Assignees: California Institute of Technology, Clarkson University
    Inventors: Yang Yang, Michael R. Hoffmann
  • Publication number: 20230182073
    Abstract: A system for capturing CO2 gas comprising: a gaseous feed stream having an initial concentration of the CO2 gas; wherein the gaseous feed stream is provided to a first reactor as a gaseous reaction stream; the first reactor comprising a sorbent composition and the gaseous reaction stream flowing therein, the gaseous reaction stream being in contact with the sorbent composition; and a first gaseous output stream having a concentration of CO2 being less than the initial concentration of CO2; wherein: the gaseous reaction stream comprises the CO2 gas and is characterized by a relative humidity of at least 5%; the sorbent composition comprises a metal carbonate material that reacts with the CO2 gas of the gaseous reaction stream thereby reducing CO2 gas concentration; and the first reactor comprises 35 wt. % or less of liquid water by weight of sorbent and liquid water.
    Type: Application
    Filed: December 9, 2022
    Publication date: June 15, 2023
    Inventors: Alan Yalun GU, Heng DONG, Leopold DOBELLE, Clement A. CID, Michael R. HOFFMANN
  • Publication number: 20220227645
    Abstract: The systems and methods for wastewater treatment comprise a porous substrate with photocatalytic material(s), and optionally electrocatalytic material(s), for generation of hydroxyl radicals that decompose contaminants in wastewater. The systems and methods intentionally facilitate the photocatalytic and/or electrocatalytic generation of oxygen bubbles, which facilitate an increase in concentration of hydroxyl radicals and shrink the liquid layer of wastewater at photocatalytic and/or electrocatalytic surfaces where hydroxyl radicals are generated in order to decrease quenching of hydroxyl radicals and simultaneously increase utilization or efficiency of the hydroxyl radicals for decomposition of contaminants. In embodiments, the systems and methods prolong hydroxyl radical lifetime and enhance water treatment performance for residential, commercial, municipal, medical, and/or industrial applications.
    Type: Application
    Filed: December 13, 2021
    Publication date: July 21, 2022
    Inventors: Lifeng YIN, Alan Yalun GU, Michael R. HOFFMANN
  • Publication number: 20220220541
    Abstract: A method and system are disclosed for detecting microbial pathogens in a sample suspected of containing the pathogens. The method includes combining loop-mediated isothermal amplification (LAMP) reagents and a polymer gel, such as a hydrogel, together with the sample to form a mixture. The gel polymerizes over a short time to immobilize the viral particles within the mixture. If target DNA/RNA are present in the sample, amplicons are produced. The target microorganisms are detected by visually detecting the presence or absence of the amplicons. The target microorganism concentrations may be determined based on the number of fluorescent amplicon dots after the reaction using a smartphone or a fluorescent microscope. The method may be employed for rapidly and inexpensively quantifying microbial pathogens in environmental water samples with high sensitivity.
    Type: Application
    Filed: March 30, 2022
    Publication date: July 14, 2022
    Inventors: Xiao Huang, Michael R. Hoffmann
  • Publication number: 20220162686
    Abstract: Disclosed herein is a membrane-based, in-gel loop-mediated isothermal amplification (LAMP) system, kit and method for detection of a target microorganism in a sample suspected of containing the microorganism. LAMP reagents, a lysing agent and a hydrogel are placed together on a filter membrane loaded with a pre-filtered sample. The hydrogel polymerizes over a short time to immobilize any target DNA/RNA particles on the membrane. The system may include a compact, portable device that integrates heat incubation and fluorescence illumination, and also a cloud-based smartphone image analysis application for quantitative results interpretation. If target DNA/RNA are present in the sample, fluorescent amplicons are produced as a result of LAMP reaction. The target microorganisms are detected by visually detecting the presence or absence of the amplicons.
    Type: Application
    Filed: October 22, 2021
    Publication date: May 26, 2022
    Inventors: Michael R. Hoffmann, Jing Li, Yanzhe Zhu, Xunyi Wu, Alan Yalun Gu, Leopold Dobelle, Clement A. Cid
  • Patent number: 11299789
    Abstract: A method and system are disclosed for detecting microbial pathogens in a sample suspected of containing the pathogens. The method includes combining loop-mediated isothermal amplification (LAMP) reagents and a polymer gel, such as a hydrogel, together with the sample to form a mixture. The gel polymerizes over a short time to immobilize the viral particles within the mixture. If target DNA/RNA are present in the sample, amplicons are produced. The target microorganisms are detected by visually detecting the presence or absence of the amplicons. The target microorganism concentrations may be determined based on the number of fluorescent amplicon dots after the reaction using a smartphone or a fluorescent microscope. The method may be employed for rapidly and inexpensively quantifying microbial pathogens in environmental water samples with high sensitivity.
    Type: Grant
    Filed: December 31, 2018
    Date of Patent: April 12, 2022
    Assignee: California Institute of Technology
    Inventors: Xiao Huang, Michael R. Hoffmann
  • Patent number: 11198982
    Abstract: A skid wheel system that has a shoe with two wheels attached. The first wheel is positioned adjacent to one side of the shoe and the second wheel is positioned adjacent to the other. The skid shoe has at least one connection opening to connect the skid shoe to a snow removal device. The circumferential edges of the wheels extend past at least the bottom, and protrude beyond the sides of the skid shoe, so as to protect the bottom, front and rear of the housing of the snow removal device from contact with concrete seams, and other uneven surfaces. The wheels can also, extend past the top of the shoe, so the system can be removed, rotated, and reattached in the event the bottom of the shoe wears to the point of no longer protecting the bottom of the snow removal device.
    Type: Grant
    Filed: June 20, 2019
    Date of Patent: December 14, 2021
    Inventor: Michael R. Hoffmann
  • Publication number: 20210180116
    Abstract: A membrane, method and system are disclosed for rapid, sensitive and precise detection of an agent suspected of being present in a sample. The agent may be a cell or microorganism, e.g., a single pathogenic bacteria, and the sample may be small, e.g., milliliters of unprocessed environmental water. The sample is processed by filtering it through an asymmetric membrane having multiple layers. One layer has microchannels for capturing the agent and another layer has nanochannels for passing particles smaller than the agent. Amplification reagents, such as loop-mediated isothermal amplification (LAMP) reagents, are load onto membrane so that the microchannels act as nanoreactors, creating quantifiable amplicons within the pores on the exposed surface of the membrane in response to captured agent. The amplicons may be imaged and counted using a fluorescent camera. The membrane is capable of agent capture, concentration, purification, partition, lysis and digital LAMP without off-membrane sample treatments.
    Type: Application
    Filed: August 28, 2019
    Publication date: June 17, 2021
    Inventors: Michael R. Hoffmann, Xingyu Lin, Xiao Huang
  • Patent number: 11028491
    Abstract: An electrolysis electrode includes a metal-doped array of nanotubes formed on a substrate. The nanotube array (NTA) may be a stabilized metal-doped black TiO2 NTA formed on a titanium substrate, and the metal dopant may include any suitable metal, for example, cobalt. The metal dopant improves the reactivity of the electrode and enhances its service life. The metal-doped NTA electrode may provide improved chlorine evolution and/or oxygen evolution activity for electrochemical wastewater treatment. The electrode may also be useful for water splitting applications. Increasing the loading of the metal dopant may lead to the formation of a metal oxide layer on top of the NTA, which improves oxygen evolution reaction (OER) overpotential.
    Type: Grant
    Filed: August 13, 2018
    Date of Patent: June 8, 2021
    Assignee: California Institute of Technology
    Inventors: Michael R. Hoffmann, Yang Yang
  • Patent number: 10894724
    Abstract: A self-diagnostic maintenance system for wastewater treatment employs unique environmental sensor configurations to link operational states of a water treatment system with unique failure modes of the system. Upon detection of failure modes, the maintenance system alerts users and operators via a short messaging service (SMS) of the problem, and can display step-by-step pictorial repair instructions for the operator to replace broken or malfunctioning parts, without the operator needing to diagnosis the problem or understand the detailed workings of the wastewater treatment system.
    Type: Grant
    Filed: July 7, 2016
    Date of Patent: January 19, 2021
    Assignee: California Institute of Technology
    Inventors: Cody E. Finke, Clement A. Cid, Michael R. Hoffmann, Anastasia K. Hanan, Donald Harvey Pinkston, III, Michael Christopher Vanier
  • Patent number: 10894254
    Abstract: A portable pathogen analysis system (PPAS) designed to detect microbial pathogens at the point-of-sample collection. The system comprises a concentration tube used for the concentration of microbes in large volumes of water samples using super absorbent polymer (SAP) beads and a hand-powered centrifuge; and a processing component, which functions as a portable lab-on-a-disc droplet digital nucleic acid amplification system, which integrates DNA extraction, nucleic acid amplification, and post-amplicon analysis in a single unit. The present invention provides a fast, cost-effective, and user-friendly solution for microbial water quality analysis in low-resource settings.
    Type: Grant
    Filed: October 5, 2018
    Date of Patent: January 19, 2021
    Assignees: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Sunny Jiang, Hamsa Gowda, Xiao Huang, Xunyi Wu, Marc Madou, Michael R. Hoffmann
  • Publication number: 20200407248
    Abstract: Aspects of the invention include a porous and water-permeable electrode for electrocatalysis comprising: a porous and water-permeable reactive electrochemical membrane (“REM”) comprising: a porous and water-permeable support membrane; wherein the support membrane comprises a titanium metal; and an electrocatalytic coating on at least a portion of the metal support membrane, the electrocatalytic coating being a tin oxide bilayer comprising: a first layer adjacent to and directly contacting the metal support membrane; wherein the first layer comprises tin oxide doped with antimony; and a second layer adjacent to and directly contacting the first layer; wherein the second layer forms a surface of the REM such that the second layer is in direct contact with an aqueous solution when the REM is in contact with the aqueous solution; wherein the second layer comprises tin oxide doped with antimony and nickel or cerium. Preferably, the support membrane is formed of a titanium metal.
    Type: Application
    Filed: June 25, 2020
    Publication date: December 31, 2020
    Inventors: Yang YANG, Michael R. Hoffmann
  • Publication number: 20190390423
    Abstract: The present invention relates to a skid wheel system that has a skid shoe and a first skid wheel and a second skid wheel. The first skid wheel is positioned adjacent a first side of the skid shoe and the second skid wheel is positioned adjacent a second side of the skid shoe. The skid shoe has at least one connection opening that is configured to connect the skid shoe to a snow removal device with a connection member. The circumferential edge of the first skid wheel and the second skid wheel extends past at least a bottom of the skid shoe in order to mitigate wear and damage caused by engagement of a ground surface with the skid shoe and the snow removal device while improving traversal of the snow removal device over the ground surface.
    Type: Application
    Filed: June 20, 2019
    Publication date: December 26, 2019
    Inventor: Michael R. Hoffmann
  • Publication number: 20190203268
    Abstract: A method and system are disclosed for detecting microbial pathogens in a sample suspected of containing the pathogens. The method includes combining loop-mediated isothermal amplification (LAMP) reagents and a polymer gel, such as a hydrogel, together with the sample to form a mixture. The gel polymerizes over a short time to immobilize the viral particles within the mixture. If target DNA/RNA are present in the sample, amplicons are produced. The target microorganisms are detected by visually detecting the presence or absence of the amplicons. The target microorganism concentrations may be determined based on the number of fluorescent amplicon dots after the reaction using a smartphone or a fluorescent microscope. The method may be employed for rapidly and inexpensively quantifying microbial pathogens in environmental water samples with high sensitivity.
    Type: Application
    Filed: December 31, 2018
    Publication date: July 4, 2019
    Inventors: Xiao Huang, Michael R. Hoffmann
  • Publication number: 20190105653
    Abstract: A portable pathogen analysis system (PPAS) designed to detect microbial pathogens at the point-of-sample collection. The system comprises a concentration tube used for the concentration of microbes in large volumes of water samples using super absorbent polymer (SAP) beads and a hand-powered centrifuge; and a processing component, which functions as a portable lab-on-a-disc droplet digital nucleic acid amplification system, which integrates DNA extraction, nucleic acid amplification, and post-amplicon analysis in a single unit. The present invention provides a fast, cost-effective, and user-friendly solution for microbial water quality analysis in low-resource settings.
    Type: Application
    Filed: October 5, 2018
    Publication date: April 11, 2019
    Inventors: Sunny Jiang, Hamsa Gowda, Xiao Huang, Xunyi Wu, Marc Madou, Michael R. Hoffmann
  • Publication number: 20190048481
    Abstract: An electrolysis electrode includes a metal-doped array of nanotubes formed on a substrate. The nanotube array (NTA) may be a stabilized metal-doped black TiO2 NTA formed on a titanium substrate, and the metal dopant may include any suitable metal, for example, cobalt. The metal dopant improves the reactivity of the electrode and enhances its service life. The metal-doped NTA electrode may provide improved chlorine evolution and/or oxygen evolution activity for electrochemical wastewater treatment. The electrode may also be useful for water splitting applications. Increasing the loading of the metal dopant may lead to the formation of a metal oxide layer on top of the NTA, which improves oxygen evolution reaction (OER) overpotential.
    Type: Application
    Filed: August 13, 2018
    Publication date: February 14, 2019
    Inventors: Michael R. Hoffmann, Yang Yang
  • Publication number: 20180354821
    Abstract: A water purification anode has a first semiconductor contacting a second semiconductor at a heterojunction. The second semiconductor includes TiO2 and excludes bismuth and niobium. The first semiconductor includes iridium. In some instances, the anode includes a current collector in direct physical contact with the first semiconductor. The anode can be arranged in water such that at least one face of the second semiconductor is in direct physical contact with the water.
    Type: Application
    Filed: August 21, 2018
    Publication date: December 13, 2018
    Inventors: Michael R. Hoffmann, Kangwoo Cho
  • Patent number: 10059607
    Abstract: A water purification anode has a first semiconductor contacting a second semiconductor at a heterojunction. The second semiconductor includes TiO2 and excludes bismuth and niobium. The first semiconductor includes iridium. In some instances, the anode includes a current collector in direct physical contact with the first semiconductor. The anode can be arranged in water such that at least one face of the second semiconductor is in direct physical contact with the water.
    Type: Grant
    Filed: January 28, 2015
    Date of Patent: August 28, 2018
    Assignee: The California Institute of Technology
    Inventors: Michael R. Hoffmann, Kangwoo Cho
  • Publication number: 20180222781
    Abstract: A water purification electrode composed of a porous carbon material is disclosed. The electrode may be used as a flow-through cathode in an electro-peroxone process providing high H2O2 production activity for electrochemical wastewater treatment. The porous carbon material is a binding agent-free carbon structure that enables H2O2 to be electro-generated in situ at cathode. The porous carbon material may be synthesized from resorcinol and can provide a relatively large reaction surface area of 200-800 m2/g. The porous carbon material also achieves low energy consumption as well as a wide pH working range, making it suitable for treating many types of organic, inorganic, and biological contaminants in water. The electrode may be integrated with an anode, ozone generator, and other components into a compact, integrated water purification system.
    Type: Application
    Filed: February 9, 2018
    Publication date: August 9, 2018
    Inventors: Kai Liu, Michael R. Hoffmann
  • Publication number: 20180087164
    Abstract: The disclosure provides for thin films that can be used to tune the catalytic characteristics of heterogeneous electrocatalysts.
    Type: Application
    Filed: September 28, 2017
    Publication date: March 29, 2018
    Inventors: Cody E. Finke, Michael R. Hoffmann, Justin Jasper, Laleh Majari Kasmaee, Stefan Omelchenko