Patents by Inventor Michael R. Loso

Michael R. Loso has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PYRIDINE AND PYRIMIDINE CARBOXYLATE HERBICIDES AND METHODS OF USE THEREOF
    Publication number: 20230017045
    Abstract: Provided herein are pyridine and pyrimidine carboxylates and their derivatives, and compositions and methods of use thereof as herbicides.
    Type: Application
    Filed: October 26, 2018
    Publication date: January 19, 2023
    Applicant: Dow AgroSciences LLC
    Inventors: Jared Bell, Ann M. Buysse, John F. Daeuble, Joseph D. Eckelbarger, Jeffrey B. Epp, Nicholas M. Irvine, Jeremy Kister, William C. Lo, Michael R. Loso, Christian T. Lowe, John C. Rohanna, Norbert M. Satchivi, Thomas L. Siddall, Kimberly M. Steward, Carla N. Yerkes
  • ANTIFUNGAL COMPOUNDS
    Publication number: 20210360921
    Abstract: The present invention relates to compounds of Formula (I): wherein R1 is as defined herein, or an acceptable salt, solvate, prodrug or hydrate thereof. The compounds of Formula I are inhibitors of metalloenzymes, such as lanosterol demethylase (CYP51).
    Type: Application
    Filed: June 3, 2021
    Publication date: November 25, 2021
    Applicant: Mycovia Pharmaceuticals, Inc.
    Inventors: William J. Hoekstra, Christopher M. Yates, Robert J. Schotzinger, Michael R. Loso, Gary D. Gustafson, Michael T. Sullenberger, Kimberly Steward, Javier Delgado, Xuelin Wang
  • Antifungal compounds
    Patent number: 11051514
    Abstract: The present invention relates to compounds of Formula (I): wherein R1 is as defined herein, or an acceptable salt, solvate, prodrug or hydrate thereof. The compounds of Formula I are inhibitors of metalloenzymes, such as lanosterol demethylase (CYP51).
    Type: Grant
    Filed: May 17, 2016
    Date of Patent: July 6, 2021
    Assignee: Mycovia Pharmaceuticals, Inc.
    Inventors: William J. Hoekstra, Christopher M. Yates, Robert J. Schotzinger, Michael R. Loso, Gary D. Gustafson, Michael T. Sullenberger, Kimberly Steward, Javier Delgado, Xuelin Wang
  • Metalloenzyme inhibitor compounds as fungicides
    Patent number: 10167300
    Abstract: The instant invention describes compounds of Formula I having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
    Type: Grant
    Filed: March 7, 2018
    Date of Patent: January 1, 2019
    Assignee: Dow AgroSciences LLC
    Inventors: Michael R. Loso, Gary D. Gustafson, Asako Kubota, Maurice C. Yap, Zachary A. Buchan, Kimberly M. Steward, Michael T. Sullenberger, William J. Hoekstra, Christopher M. Yates
  • METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES
    Publication number: 20180298038
    Abstract: The instant invention describes compounds of Formula I having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
    Type: Application
    Filed: March 7, 2018
    Publication date: October 18, 2018
    Inventors: Michael R. Loso, Gary D. Gustafson, Asako Kubota, Maurice C. Yap, Zachary A. Buchan, Kimberly M. Steward, Michael T. Sullenberger, William J. Hoekstra, Christopher M. Yates
  • METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES
    Publication number: 20180290998
    Abstract: The instant invention describes compounds of Formula I having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
    Type: Application
    Filed: April 4, 2018
    Publication date: October 11, 2018
    Inventors: Michael R. Loso, Gary D. Gustafson, Asako Kubota, Maurice C. Yap, Zachary A. Buchan, Kimberly M. Steward, Michael T. Sullenberger, William J. Hoekstra, Christopher M. Yates
  • Metalloenzyme inhibitor compounds as fungicides
    Patent number: 9957252
    Abstract: The instant invention describes compounds of Formula I having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
    Type: Grant
    Filed: May 4, 2017
    Date of Patent: May 1, 2018
    Assignee: Dow AgroSciences LLC
    Inventors: Michael R. Loso, Gary D. Gustafson, Asako Kubota, Maurice C. Yap, Zachary A. Buchan, Kimberly M. Steward, Michael T. Sullenberger, William J. Hoekstra, Christopher M. Yates
  • Metalloenzyme inhibitor compounds as fungicides
    Patent number: 9944664
    Abstract: The instant invention describes compounds of Formula I having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
    Type: Grant
    Filed: April 10, 2015
    Date of Patent: April 17, 2018
    Assignee: Dow AgroSciences LLC
    Inventors: Michael R. Loso, Gary D. Gustafson, Asako Kubota, Maurice C. Yap, Zachary A. Buchan, Kimberly M. Steward, Michael T. Sullenberger, William J. Hoekstra, Christopher M. Yates
  • METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES
    Publication number: 20170233369
    Abstract: The instant invention describes compounds of Formula I having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
    Type: Application
    Filed: May 4, 2017
    Publication date: August 17, 2017
    Inventors: Michael R. Loso, Gary D. Gustafson, Asako Kubota, Maurice C. Yap, Zachary A. Buchan, Kimberly M. Steward, Michael T. Sullenberger, William J. Hoekstra, Christopher M. Yates
  • PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO
    Publication number: 20170158674
    Abstract: This document discloses molecules having the following formula (“Formula One”): and processes associated therewith.
    Type: Application
    Filed: February 17, 2017
    Publication date: June 8, 2017
    Applicant: Dow AgroSciences LLC
    Inventors: James E. Hunter, William C. Lo, Gerald B. Watson, Akshay Patny, Gary D. Gustafson, Dan Pernich, William K. Brewster, Debra L. Camper, Beth Lorsbach, Michael R. Loso, Thomas C. Sparks, Hemant Joshi, Adiraj Mandaleswaran, Ramadevi Sanam, Rambabu Gundla, Pravin S. Iyer
  • Metalloenzyme inhibitor compounds as fungicides
    Patent number: 9663491
    Abstract: The instant invention describes compounds of Formula I having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
    Type: Grant
    Filed: April 10, 2015
    Date of Patent: May 30, 2017
    Assignee: Dow AgroSciences LLC
    Inventors: Michael R. Loso, Gary D. Gustafson, Asako Kubota, Maurice C. Yap, Zachary A. Buchan, Kimberly M. Steward, Michael T. Sullenberger, William J. Hoekstra, Christopher M. Yates
  • Pesticidal compositions and processes related thereto
    Patent number: 9615576
    Abstract: This document discloses molecules having the following formula (“Formula One”): and processes associated therewith.
    Type: Grant
    Filed: March 25, 2014
    Date of Patent: April 11, 2017
    Assignee: Dow AgroSciences LLC
    Inventors: James E. Hunter, William C. Lo, Gerald B. Watson, Akshay Patny, Gary D. Gustafson, Dan Pernich, William K. Brewster, Debra L. Camper, Beth Lorsbach, Michael R. Loso, Thomas C. Sparks, Hemant Joshi, Adiraj Mandaleswaran, Ramadevi Sanam, Rambabu Gundla, Pravin S. Iyer
  • Metalloenzyme inhibitor compounds
    Patent number: 9556143
    Abstract: The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
    Type: Grant
    Filed: December 1, 2014
    Date of Patent: January 31, 2017
    Assignee: Viamet Pharmaceuticals, Inc.
    Inventors: William J. Hoekstra, Stephen W. Rafferty, Christopher M. Yates, Robert J. Schotzinger, Michael R. Loso, Michael T. Sullenberger
  • Fungicidal compositions
    Patent number: 9447073
    Abstract: The instant invention describes tetrazole compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
    Type: Grant
    Filed: May 28, 2014
    Date of Patent: September 20, 2016
    Assignee: Viamet Pharmaceuticals, Inc.
    Inventors: William J. Hoekstra, Michael R. Loso, Gary D. Gustafson, Daniel Knueppel, Zachary A. Buchan, Michael T. Sullenberger
  • FUNGICIDAL COMPOSITIONS
    Publication number: 20160102072
    Abstract: The instant invention describes tetrazole compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
    Type: Application
    Filed: May 28, 2014
    Publication date: April 14, 2016
    Inventors: William Hoekstra, Michael R. Loso, Gary D. Gustafson, Daniel Knueppel, Zachary A. Buchan, Michael T. Sullenberger
  • Metalloenzyme inhibitor compounds
    Patent number: 9221791
    Abstract: The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
    Type: Grant
    Filed: August 12, 2014
    Date of Patent: December 29, 2015
    Assignee: Viamet Pharmaceuticals, Inc.
    Inventors: William J. Hoekstra, Stephen W. Rafferty, Christopher M. Yates, Robert J. Schotzinger, Michael R. Loso, Michael T. Sullenberger, Gary D. Gustafson
  • Metalloenzyme inhibitor compounds
    Patent number: 9220265
    Abstract: The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
    Type: Grant
    Filed: June 5, 2014
    Date of Patent: December 29, 2015
    Assignee: Viamet Pharmaceuticals, Inc.
    Inventors: William J. Hoekstra, Christopher M. Yates, Robert J. Schotzinger, Michael R. Loso, Zachary A. Buchan, Michael T. Sullenberger, Gary D. Gustafson
  • METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES
    Publication number: 20150291632
    Abstract: The instant invention describes compounds of Formula I having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
    Type: Application
    Filed: April 10, 2015
    Publication date: October 15, 2015
    Inventors: Michael R. Loso, Gary D. Gustafson, Asako Kubota, Maurice C. Yap, Zachary A. Buchan, Kimberly M. Steward, Michael T. Sullenberger, William J. Hoekstra, Christopher M. Yates
  • METALLOENZYME INHIBITOR COMPOUNDS AS FUNGICIDES
    Publication number: 20150291557
    Abstract: The instant invention describes compounds of Formula I having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
    Type: Application
    Filed: April 10, 2015
    Publication date: October 15, 2015
    Inventors: Michael R. Loso, Gary D. Gustafson, Asako Kubota, Maurice C. Yap, Zachary A. Buchan, Kimberly M. Steward, Michael T. Sullenberger, William J. Hoekstra, Christopher M. Yates
  • METALLOENZYME INHIBITOR COMPOUNDS
    Publication number: 20150246898
    Abstract: The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes. Living organisms have developed tightly regulated processes that specifically import metals, transport them to intracellular storage sites and ultimately transport them to sites of use. One of the most important functions of metals such as zinc and iron in biological systems is to enable the activity of metalloenzymes.
    Type: Application
    Filed: September 12, 2013
    Publication date: September 3, 2015
    Inventors: Gary D. Gustafson, William Hoekstra, Michael R. Loso, Christopher M. Yates