Abstract: Compounds having formula (I), and enantiomers, and diastereomers, stereoisomers, pharmaceutically-acceptable salts thereof, are useful as kinase modulators, including RIPK1 modulation. All the variables are as defined herein.

Abstract: The invention relates to a catalyst system suitable for hydrogenating aromatic nitro compounds (I) to form the corresponding aromatic amines (II), the catalyst system containing, as essential constituents: a component A selected from the group consisting of silicon carbide, corundum (alpha-Al2O3) and slightly porous to non-porous zirconium oxide (ZrO2); and a component B, containing B1—a carrier substance selected from the group consisting of silicon dioxide, gamma-, delta- or theta-aluminum oxide Al2O3, titanium dioxide, zirconium dioxide and graphite, B2—a metal or a plurality of metals selected from the group consisting of copper, nickel, palladium, platinum and cobalt, and optionally B3—an additional metal selected from the group consisting of at least one metal selected from main group I, main group II, main group IV and sub-groups II, V, VI and VIII of the periodic table of the elements, the proportion of component A being in the range of 5 to 60 wt %, in relation to the total weight of the catalyst sys

Abstract: The present invention relates to a process for carrying out a chemical reaction in a chemical reactor, in which at least one starting material, which is an organic chemical compound comprising 1 to 80 carbon atoms, is converted into at least one reaction product in a fluid phase in the presence of a film comprising solid catalyst particles, which catalyze said chemical reaction, and comprising an organic polymer in fibrillated form, wherein the mass fraction of the sum of the starting material and of the reaction product based on the total mass of the fluid phase is in the range from 0.01 to 1.

Abstract: Described herein are enhancements for managing multi-host Peripheral Component Interconnect Express (PCIe) switching. In one implementation, a PCIe switch coupled to a host processing system and PCIe slots may receive enumeration requests from the host processing system to identify available PCIe devices. In response to the enumeration requests, the PCIe switch may transfer responses to the host processing system indicating device identifier information for PCIe devices associated with the PCIe slots even if one or more of the PCIe devices is not currently installed.

Abstract: Described herein are enhancements for managing multi-host Peripheral Component Interconnect Express (PCIe) switching. In one implementation, a PCIe switch coupled to a host processing system and PCIe slots may receive enumeration requests from the host processing system to identify available PCIe devices.

Abstract: Process for preparing monoethylene glycol (MEG) by metal-catalyzed reaction of a dialkyl oxalate of the formula I where R1 and R2 are each, independently of one another, methyl, ethyl, n-propyl or isopropyl, with hydrogen (H2), wherein the dialkyl oxalate (I) is used as melt or as a solution in a solvent, dialkyl oxalate (I) and H2 are used in a molar ratio of H2:dialkyl oxalate (I) in the range from 4.0 to 30 and the reaction is carried out continuously in a reactor at a cross-sectional loading of ?10 m/s, a temperature in the range from 150 to 270° C., a pressure in the range from 150 to 390 bar and in the presence of a chromium-free heterogeneous catalyst comprising copper.

Abstract: Process for preparing monoethylene glycol (MEG) by metal-catalyzed reaction of a dialkyl oxalate of the formula I where R1 and R2 are each, independently of one another, methyl, ethyl, n-propyl or isopropyl, with hydrogen (H2), wherein the dialkyl oxalate (I) is used as melt or as a solution in a solvent, dialkyl oxalate (I) and H2 are used in a molar ratio of H2: dialkyl oxalate (I) in the range from 4.0 to 30 and the reaction is carried out continuously in a reactor at a cross-sectional loading of 10 m/s, a temperature in the range from 150 to 270° C., a pressure in the range from 150 to 390 bar and in the presence of a chromium-free heterogeneous catalyst comprising copper.

Abstract: A process for obtaining pure aniline contains catalytically hydrogenating nitrobenzene, to obtain a reaction mixture, separating the reaction mixture into a gas phase containing hydrogen and a liquid phase, liquid/liquid phase separating the liquid phase to obtain an aqueous phase and also crude aniline containing water as an organic phase, distillatively pre-purifying the crude aniline by removing the water via an overhead stream of a first distillation column to obtain a first bottom stream, feeding the first bottom stream as a feed stream to a pure column from which a pure aniline stream is taken off at the top and a second bottom stream containing high boilers is taken off, and passing the second bottom stream to incineration, by pumping the second bottom stream through heated pipelines and by adding methanol, ethanol, propanol, and/or acetone to the second bottom stream.

Abstract: A process for obtaining pure aniline contains catalytically hydrogenating nitrobenzene, to obtain a reaction mixture, separating the reaction mixture into a gas phase containing hydrogen and a liquid phase, liquid/liquid phase separating the liquid phase to obtain an aqueous phase and also crude aniline containing water as an organic phase, distillatively pre-purifying the crude aniline by removing the water via an overhead stream of a first distillation column to obtain a first bottom stream, feeding the first bottom stream as a feed stream to a pure column from which a pure aniline stream is taken off at the top and a second bottom stream containing high boilers is taken off, and passing the second bottom stream to incineration, by pumping the second bottom stream through heated pipelines and by adding methanol, ethanol, propanol, and/or acetone to the second bottom stream.

Abstract: A sensor arrangement for determining an inside temperature in a motor vehicle having a climate control device and at least a panel is at least a part of a control part of the climate control device, where the sensor arrangement includes a housing with at least a front wall and a rear wall, the housing is filled with a heat-insulating material, a first temperature sensor attached to a rear of the front wall and a second temperature sensor attached to an inner side of the rear wall, said inner side facing a rear of the front wall, and where the front wall is a part of the panel of the motor vehicle.

Abstract: A sensor arrangement for determining an inside temperature in a motor vehicle having a climate control device and at least a panel is at least a part of a control part of the climate control device, where the sensor arrangement includes a housing with at least a front wall and a rear wall, the housing is filled with a heat-insulating material, a first temperature sensor attached to a rear of the front wall and a second temperature sensor attached to an inner side of the rear wall, said inner side facing a rear of the front wall, and where the front wall is a part of the panel of the motor vehicle.

Abstract: A sensor arrangement is provided for determining an interior temperature in a motor vehicle, which sensor arrangement is at least one part of an air-conditioning operating part, comprising a closed housing having at least one front wall and one rear wall, wherein the front wall is manufactured from a material which ensures satisfactory thermal transfer and the housing and is filled with a thermally insulating means, further comprising a first temperature sensor which is fastened to a rear side of the front wall and a second temperature sensor which interacts with the first temperature sensor at least in relation to an evaluation of the interior temperature, wherein the at least second temperature sensor is fastened on an inner side of the rear wall which faces the rear side of the front wall.

Abstract: A sensor arrangement is provided for determining an interior temperature in a motor vehicle, which sensor arrangement is at least one part of an air-conditioning operating part, comprising a closed housing having at least one front wall and one rear wall, wherein the front wall is manufactured from a material which ensures satisfactory thermal transfer and the housing and is filled with a thermally insulating means, further comprising a first temperature sensor which is fastened to a rear side of the front wall and a second temperature sensor which interacts with the first temperature sensor at least in relation to an evaluation of the interior temperature, wherein the at least second temperature sensor is fastened on an inner side of the rear wall which faces the rear side of the front wall.