Publication number: 20070105832
Abstract: Compounds are provided which have the structure Wherein A, B, C, D, m, Y, Ra, Rc, Rd, and Rd? are as described herein, and which are useful as inhibitors of tryptase, thrombin, trypsin, Factor Xa, Factor VIIa, Factor XIa, and urokinase-type plasminogen activator and may be employed in preventing and/or treating asthma, chronic asthma, allergic rhinitis, and thrombotic disorders.
Type:
Application
Filed:
April 4, 2006
Publication date:
May 10, 2007
Inventors:
Thomas Bannister, Cassandra Celatka, Nizal Chandrakumar, Hongfeng Deng, Zihong Guo, Lei Jin, Tsvetelina Lazarova, Jian Lin, Scott Moe, Pamela Nagafuji, Manuel Navia, Amy Ripka, Michael Rynkiewicz, Kerry Spear, James Stickler, Roger Xie