Patents by Inventor Michael S. Dey

Michael S. Dey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hormone replacement therapy
    Publication number: 20090005351
    Abstract: This invention relates to methods and pharmaceutical compositions for providing hormone replacement therapy in perimenopausal, menopausal, and postmenopausal women through the continuous administration of combinations of conjugated estrogens and medroxyprogesterone acetate.
    Type: Application
    Filed: November 6, 2007
    Publication date: January 1, 2009
    Inventors: James H. Pickar, Michael S. Dey
  • Method of treating estrogen receptor positive carcinoma with 17 ?-dihydroequilin
    Patent number: 7005429
    Abstract: This invention provides a method of treating estrogen receptor positive carcinoma in a mammal in need thereof which comprises administering an antineoplastic amount of 17(?-dihydroequilin or a mammalian metabolic conjugate thereof orally, parenterally, transdermally, topically, rectally, intravaginally, intranasally, or intrabronchially. As such, the compounds of this invention are useful in treating estrogen receptor positive carcinomas such as carcinomas of the breast, uterus, ovary, fallopian tube, cervix, vagina, liver, pituitary, central nervous system, hypothalamus, bone, skin, kidney, urethra, prostate, and the like.
    Type: Grant
    Filed: September 26, 2001
    Date of Patent: February 28, 2006
    Assignee: Wyeth
    Inventors: Michael S. Dey, Frederick J. Bex, Alan Corbin
  • Hormone replacement therapy
    Publication number: 20030191097
    Abstract: This invention relates to methods and pharmaceutical compositions for providing hormone replacement therapy in perimenopausal, menopausal, and postmenopausal women through the continuous administration of combinations of conjugated estrogens and trimegestone.
    Type: Application
    Filed: April 1, 2003
    Publication date: October 9, 2003
    Applicant: Wyeth
    Inventors: Gary S. Grubb, James H. Pickar, Ginger D. Constantine, Michael S. Dey
  • Hormone replacement therapy
    Publication number: 20030191103
    Abstract: This invention relates to methods and pharmaceutical compositions for providing hormone replacement therapy in perimenopausal, menopausal, and postmenopausal women through the continuous administration of combinations of conjugated estrogens and trimegestone.
    Type: Application
    Filed: April 1, 2003
    Publication date: October 9, 2003
    Applicant: Wyeth
    Inventors: Gary S. Grubb, James H. Pickar, Ginger D. Constantine, Michael S. Dey
  • Method of treating estrogen receptor positive carcinoma 17 alpha-dihydroequilin
    Publication number: 20020035101
    Abstract: This invention provides a method of treating estrogen receptor positive carcinoma in a mammal in need thereof which comprises administering an antineoplastic amount of 17(&agr;-dihydroequilin or a mammalian metabolic conjugate thereof orally, parenterally, transdermally, topically, rectally, intravaginally, intranasally, or intrabronchially. As such, the compounds of this invention are useful in treating estrogen receptor positive carcinomas such as carcinomas of the breast, uterus, ovary, fallopian tube, cervix, vagina, liver, pituitary, central nervous system, hypothalamus, bone, skin, kidney, urethra, prostate, and the like.
    Type: Application
    Filed: September 26, 2001
    Publication date: March 21, 2002
    Applicant: American Home Products Corporation
    Inventors: Michael S. Dey, Frederick J. Bex, Alan Corbin
  • Method of treating estrogen receptor positive carcinoma with 17 &agr;-dihydroequilin
    Patent number: 6342491
    Abstract: This invention provides a method of treating estrogen receptor positive carcinoma in a mammal in need thereof which comprises administering an antineoplastic amount of 17&agr;-dihydroequilin or a mammalian metabolic conjugate thereof orally, parenterally, transdermally, topically, rectally, intravaginally, intranasally, or intrabronchially. As such, the compounds of this invention are useful in treating estrogen receptor positive carcinomas such as carcinomas of the breast, uterus, ovary, fallopian tube, cervix, vagina, liver, pituitary, central nervous system, hypothalamus, bone, skin, kidney, urethra, prostate, and the like.
    Type: Grant
    Filed: November 10, 1992
    Date of Patent: January 29, 2002
    Assignee: American Home Products Corporation
    Inventors: Michael S. Dey, Frederick J. Bex, Alan Corbin
  • Method of lowering cholesterol
    Patent number: 5510342
    Abstract: This invention provides a method of lowering cholesterol and blood lipid levels, preventing hypercholesterolemia, hyperlipidemia, cardiovascular disease, atherosclerosis, and peripheral vascular disease comprising administering an effective amount of 17.alpha.-dihydroequilenin or a mammalian metabolic conjugate thereof to a mammal in need thereof.
    Type: Grant
    Filed: March 15, 1995
    Date of Patent: April 23, 1996
    Assignees: American Home Products Corporation, Wake Forest University
    Inventors: Scott A. Washburn, Thomas B. Clarkson, Steven J. Adelman, Michael S. Dey