Abstract: A guiding catheter for providing proximal occlusion while intubating a branch vessel lumen in a patient. The catheter comprises an elongate hollow shaft having open proximal and distal ends and a resiliently compressible occluder fixed about the shaft adjacent the distal end, the occluder having a relaxed shape that tapers distally from a major diameter greater than a diameter of the vessel lumen. The occluder may comprise elastic foam material or an impermeable flexible cover clingingly enclosing a resilient support member.

Abstract: A guiding catheter for providing proximal occlusion while intubating a branch vessel lumen in a patient. The catheter comprises an elongate hollow shaft having open proximal and distal ends and a resiliently compressible occluder fixed about the shaft adjacent the distal end, the occluder having a relaxed shape that tapers distally from a major diameter greater than a diameter of the vessel lumen. The occluder may comprise elastic foam material or an impermeable flexible cover clingingly enclosing a resilient support member.

Abstract: A system for treating a vascular condition, including a hollow guidewire, a core wire inserted through the hollow guidewire, and an embolic containment device. The core wire includes a tapered undulating section carried within the hollow guidewire. The embolic containment device is coupled between a distal end of the hollow guidewire and a distal end of the core wire. The tapered undulating section of the core wire provides frictional control of the embolic containment device based on a direction of core wire translation within the hollow guidewire. A method of treating a vascular condition and a guidewire-based embolic filter system are also disclosed.

Abstract: A control handle for an intraluminal device includes a handle housing having a first end and a second end, the handle housing having a lumen. A roller assembly is disposed at a first end of the lumen. The roller assembly comprises a first roller and a base. The lumen is interposed between the first roller and the base. A clamp assembly is disposed at the second end of the lumen. The clamp assembly comprises a first clamp element and a second clamp element. The lumen is interposed between the first clamp element and the second clamp element. A closure mechanism is configured to effect movement between the first clamp element and the second clamp element and between the first roller and the base. The control handle further includes a turn device operably connected to the roller assembly.

Abstract: A control handle for an intraluminal device comprises a handle housing having a first end and a second end, the handle housing having a lumen. A roller assembly is disposed at a first end of the lumen. The roller assembly comprises a first roller and a base. The lumen is interposed between the first roller and the base. A clamp assembly is disposed at the second end of the lumen. The clamp assembly comprises a first clamp element and a second clamp element. The lumen is interposed between the first clamp element and the second clamp element. A closure mechanism is configured to effect movement between the first clamp element and the second clamp element and between the first roller and the base. The control handle further comprises a turn device operably connected to the roller assembly.

Abstract: The present invention is a distal protection device for use during a vascular treatment, such as angioplasty or atherectomy. A filter assembly located on the distal end of a delivery member is deployed distally of the vascular region to be treated to capture emboli released during and immediately after the procedure. The filter is then retracted to retain any captured emboli and then removed from the patient.

Abstract: Methods of fabricating medical vascular catheters adapted to be inserted into a blood vessel from an incision through the skin of a patient for introducing other devices or fluids for diagnostic or therapeutic purposes and particularly methods for fabricating such catheters with catheter bodies having catheter sections of differing flexibility are disclosed.

Abstract: A guide wire apparatus for prevention of distal atheroembolization during percutaneous catheter intervention procedures, such as angioplasty or stent deployment. An expandable protection element, such as a self-expanding or self-collapsing filter or occluder, is mountable adjacent the distal end of a core wire, which can guide a therapeutic catheter. Relative displacement of the ends of the protection element causes transformation of the protection element between a closed configuration and an expanded configuration that spans the vessel to be treated. An operator rod, which may be a hollow rod or an interventional catheter, may be slidably disposed over the core wire to engage with and either push or pull the proximal end of the protection element to cause transformation thereof.

Abstract: A hub for connecting a medical catheter in fluid communication with a medical device, such as a syringe, includes a tubular shaped body member which has an outer surface that is formed with a plurality of grips. The hub also has a pair or diametrically opposed wings which extend from the outer surface of the body member and it has a proximal end which is formed as a female luer fitting for engagement with the medical device. The distal end of the hub is formed with a spiral strain relief element having a passageway which receives the proximal end of the medical catheter. In operation, the spiral relief element supports the medical catheter and prevents kinking of the catheter near the hub during flexure of the catheter by providing for a progressive transition from the relative rigidity of the hub to the flexure required by the catheter.

Abstract: The present invention comprises a tubular catheter shaft defining at least one catheter shaft lumen and a radiopaque band made of a polymeric material loaded with a radiopaque material of greater than 40% by weight, suitable for visualization under fluoroscopy in catheters in the range of 3 French to 5 French. The distal soft tip is formed of a relatively flexible polymeric material, loaded with radiopaque material which is less radiopaque than the radiopaque band. The radiopaque band's proximal end adjoins the distal end of the catheter shaft. The radiopaque band's distal end adjoins the proximal end of the distal tip to form an attachment junction. A tubular sleeve fits coaxially over the radiopaque band, the distal end of the catheter shaft and the proximal end of the distal soft tip.

Abstract: A guidewire for use in a catheter comprising a unitary core wire, a distal tip and an elongate tube. The core wire has a body segment and a transition segment, the body segment being of substantially uniform outer diameter with a distal end serially disposed proximal to the transition segment proximal end, the transition segment being more flexible than the body segment, and progressively reduced in cross-section from the body segment. The smoothly rounded distal tip is affixed to the distal end of the transition segment. The elongate tube defines a tube lumen, the core wire transition segment extends longitudinally through the tube, the tube having a uniform outer diameter equal to the outer diameter of the body segment, the proximal end of the tube being affixed to the proximal end of the transition segment, the distal end of the tube being affixed to the distal tip. The tube may be formed of a super-elastic metallic member or formed from a synthetic resin. The tube wall thickness is preferably between 0.

Abstract: The present invention relates to a guidewire which comprises an elongated core of a substantially solid cross-section having a distal end portion, the distal end portion having a plurality of notches therein, the notches having a depth of 5-25% of the diameter of the proximal end. The proximal end of the guidewire has a diameter in the range of 0.005-0.040 inches, the notches defining a continuous helix with a constant depth. The guidewire also comprises a helically wound spring, the spring having a plurality of coils defining a lumen. At least part of the distal end portion of the elongated core being received within the lumen.

Abstract: A catheter guidewire having an elongate core wire, an elongate tube defining a tube lumen, the proximal end of the tube being affixed to the distal end of the core wire. The tube has a smooth exterior surface and one or more plug segments filling the tube lumen, each plug segment having a stiffness less than that of the core wire and less than that of the proximally preceding plug segment. The proximal end of the proximal most plug segment is affixed to the distal end of the core wire, the distal end of the tube is affixed to the distal most plug segment. A smoothly rounded distal tip extends beyond and is affixed to the distal end of the tube. The tube may be formed of a super-elastic metallic member or formed from a synthetic resin. The tube wall thickness is preferably between 0.002 inches and 0.005 inches.