Patents by Inventor Michael S. Parmacek

Michael S. Parmacek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Promoter for smooth muscle cell expression
    Patent number: 7169764
    Abstract: Disclosed is a smooth muscle cell specific promoter, the SM22? gene promoter as well as the murine cDNA and genomic SM22? nucleic acid sequences. Also disclosed are methods of preventing restenosis following balloon angioplasty and methods of treating asthma based on inhibition of smooth muscle cell proliferation by expressing cell cycle control genes, or contraction inhibiting peptides in smooth muscle cells, under the control of the SM22? promoter.
    Type: Grant
    Filed: August 29, 1997
    Date of Patent: January 30, 2007
    Assignee: Arch Development Corporation
    Inventors: Michael S. Parmacek, Julian Solway
  • Promoter smooth muscle cell expression
    Patent number: 6331527
    Abstract: Disclosed is a smooth muscle cell specific promoter, the SM22&agr; gene promoter as well as the murine cDNA and genomic SM22&agr; nucleic acid sequences. Also disclosed are methods of preventing restenosis following balloon angioplasty and methods of treating asthma based on inhibition of smooth muscle cell proliferation by expressing cell cycle control genes, or contraction inhibiting peptides in smooth muscle cells, under the control of the SM22&agr; promoter.
    Type: Grant
    Filed: November 1, 1999
    Date of Patent: December 18, 2001
    Assignee: Arch Development Corporation
    Inventors: Michael S. Parmacek, Julian Solway
  • Method for promoting angiogenesis with a nucleic acid construct comprising an SM22&agr;0 promoter
    Patent number: 6297221
    Abstract: Disclosed is a smooth muscle cell specific promoter, the SM22&agr; gene promoter as well as the murine cDNA and genomic SM22&agr; nucleic acid sequences. Also disclosed are methods of preventing restenosis following balloon angioplasty and methods of treating asthma based on inhibition of smooth muscle cell proliferation by expressing cell cycle control genes, or contraction inhibiting peptides in smooth muscle cells, under the control of the SM22&agr; promoter.
    Type: Grant
    Filed: January 5, 1999
    Date of Patent: October 2, 2001
    Assignee: Arch Development Corporation
    Inventors: Michael S. Parmacek, Julian Solway
  • Promoter for smooth muscle cell expression
    Patent number: 6291211
    Abstract: Disclosed is a smooth muscle cell specific promoter, the SM22&agr; gene promoter as well as the murine cDNA and genomic SM22&agr; nucleic acid sequences. Also disclosed are methods of preventing restenosis following balloon angioplasty and methods of treating asthma based on inhibition of smooth muscle cell proliferation by expressing cell cycle control genes, or contraction inhibiting peptides in smooth muscle cells, under the control of the SM22&agr; promoter.
    Type: Grant
    Filed: November 1, 1999
    Date of Patent: September 18, 2001
    Assignee: Arch Development Corporation
    Inventors: Michael S. Parmacek, Julian Solway
  • Method for modulating smooth muscle cell proliferation
    Patent number: 6284743
    Abstract: Disclosed is a smooth muscle cell specific promoter, the SM22&agr; gene promoter as well as the murine cDNA and genomic SM22&agr; nucleic acid sequences. Also disclosed are methods of preventing restenosis following balloon angioplasty and methods of treating asthma based on inhibition of smooth muscle cell proliferation by expressing cell cycle control genes, or contraction inhibiting peptides in smooth muscle cells, under the control of the SM22&agr; promoter.
    Type: Grant
    Filed: April 10, 2000
    Date of Patent: September 4, 2001
    Assignee: Arch Development Corporation
    Inventors: Michael S. Parmacek, Julian Solway
  • Method for modulating smooth muscle cell proliferation
    Patent number: 6114311
    Abstract: Disclosed is a smooth muscle cell specific promoter, the SM22.alpha. gene promoter as well as the murine cDNA and genomic SM22.alpha. nucleic acid sequences. Also disclosed are methods of preventing restenosis following balloon angioplasty and methods of treating asthma based on inhibition of smooth muscle cell proliferation by expressing cell cycle control genes, or contraction inhibiting peptides in smooth muscle cells, under the control of the SM22.alpha. promoter.
    Type: Grant
    Filed: February 26, 1999
    Date of Patent: September 5, 2000
    Assignee: Arch Development Corporation
    Inventors: Michael S. Parmacek, Julian Solway
  • DNA constructs and viral vectors comprising a smooth muscle promoter
    Patent number: 6090618
    Abstract: Disclosed is a smooth muscle cell specific promoter, the SM22.alpha. gene promoter as well as the murine cDNA and genomic SM22.alpha. nucleic acid sequences. Also disclosed are methods of preventing restenosis following balloon angioplasty and methods of treating asthma based on inhibition of smooth muscle cell proliferation by expressing cell cycle control genes, or contraction inhibiting peptides in smooth muscle cells, under the control of the SM22.alpha. promoter.
    Type: Grant
    Filed: October 7, 1996
    Date of Patent: July 18, 2000
    Assignee: Arch Development Corporation
    Inventors: Michael S. Parmacek, Julian Solway