Abstract: The present invention relates to formulations of dengue virus vaccine comprising at least one live, attenuated dengue virus or live, attenuated chimeric flavivirus, a buffer, a sugar, a cellulose derivative, a glycol or sugar alcohol, optionally an alkali or alkaline salt and an amino acid; and formulations of dengue virus vaccine comprising at least one live, attenuated dengue virus or live, attenuated chimeric flavivirus, a buffer, a sugar of at least 150 mg/ml, a carrier, and optionally an alkali or alkaline salt and an amino acid.

Abstract: The present disclosure relates generally to medical devices and, more particularly, to a gas mixing system for a medical ventilator. A gas mixer is provided to adjust the oxygen concentration of environmental air for a blower-based ventilator, by adjusting the mix of air upstream of the ventilator and providing the mixed air to the ventilator's environmental air inlet.

Abstract: The present invention relates to formulations of dengue virus vaccine comprising at least one live, attenuated dengue virus or live, attenuated chimeric flavivirus, a buffer, a sugar, a cellulose derivative, a glycol or sugar alcohol, optionally an alkali or alkaline salt and an amino acid; and formulations of dengue virus vaccine comprising at least one live, attenuated dengue virus or live, attenuated chimeric flavivirus, a buffer, a sugar of at least 150 mg/ml, a carrier, and optionally an alkali or alkaline salt and an amino acid.

Abstract: The present invention relates to formulations of dengue virus vaccine comprising at least one live, attenuated dengue virus or live, attenuated chimeric flavivirus, a buffer, a sugar, a cellulose derivative, a glycol or sugar alcohol, optionally an alkali or alkaline salt and an amino acid; and formulations of dengue virus vaccine comprising at least one live, attenuated dengue virus or live, attenuated chimeric flavivirus, a buffer, a sugar of at least 150 mg/ml, a carrier, and optionally an alkali or alkaline salt and an amino acid.

Abstract: The present invention relates to formulations of dengue virus vaccine comprising at least one live attenuated dengue virus or live attenuated chimeric flavivirus, a buffer, a sugar, a cellulose derivative, a glycol or sugar alcohol, optionally an alkali or alkaline salt and an amino acid; and formulations of dengue virus vaccine comprising at least one live attenuated dengue virus or live attenuated chimeric flavivirus, a buffer, a sugar of at least 150 mg/ml, a carrier, and optionally an alkali or alkaline salt and an amino acid.

Abstract: A moistening system that significantly reduces the problems caused by contaminants in the moistening fluid is provided. The catch basin of a moistening system is provided with a filter that reduces the amount of contaminants contained in the recycled moistening fluid. Additionally, the moistening fluid is buffered with an acid that acts to dissolve the paper filler and other soluble debris that may be introduced into the moistening fluid, thereby significantly decreasing any blinding of components of the moistening system that would otherwise reduce the flow rate of the moistening fluid through the system. These ensure that sufficient moistening fluid is applied to the envelope flaps, which results in consistent and complete sealing of the envelope flaps.

Abstract: A powder and gel concentrate for a sealing solution is provided. The concentrate is comprised of a biocide, dye and acid buffer. This concentrate can be hydrated or dissolved using standard tap (mineralized) water to produce a sealing solution. The acid buffer keeps the minerals in the tap water suspended in solution, thereby preventing the solid scale (mineral build-up) that would otherwise clog the filters of a sealing system.

Abstract: A powder and gel concentrate for a sealing solution is provided. The concentrate is comprised of a biocide, dye and acid buffer. This concentrate can be hydrated or dissolved using standard tap (mineralized) water to produce a sealing solution. The acid buffer keeps the minerals in the tap water suspended in solution, thereby preventing the solid scale (mineral build-up) that would otherwise clog the filters of a sealing system.

Abstract: A moistening system that significantly reduces the problems caused by contaminants in the moistening fluid is provided. The catch basin of a moistening system is provided with a filter that reduces the amount of contaminants contained in the recycled moistening fluid. Additionally, the moistening fluid is buffered with an acid that acts to dissolve the paper filler and other soluble debris that may be introduced into the moistening fluid, thereby significantly decreasing any blinding of components of the moistening system that would otherwise reduce the flow rate of the moistening fluid through the system. These ensure that sufficient moistening fluid is applied to the envelope flaps, which results in consistent and complete sealing of the envelope flaps.

Abstract: A system for monitoring railroad cars comprising a hatch cover assembly including a cover body, a sensor, a wireless transmitter for transmitting data received from the sensor, a wireless receiver for receiving the data from the wireless transmitter, and a satellite transmitter for transmitting the data to a satellite. The wireless receiver and the satellite transmitter are attached to the hatch cover assembly. In one embodiment, the sensor is a pressure sensor having a sensing unit situated in the plenum of a vented hatch cover. In another embodiment, the sensor is an air flow sensor having a sensing unit situated in the plenum of a vented hatch cover. In another embodiment, the sensor is a chain tension sensor attached to a handbrake chain. In another embodiment, the sensor is a hatch cover position attached to the hatch cover assembly.

Abstract: A vented hatch cover comprising a cover body, an intake filter element, and a discharge filter element includes a plurality of walls defining an air intake passage, and an air discharge passage, an inner rim and an outer rim with a plurality of ribs extending across the air intake passage. The intake filter element includes a plurality of latches engaging the ribs. The discharge filter element includes an outer disc portion with a radially outer edge having a rim with a plurality of latches that releasably secure the discharge filter element to the inner rim of the cover body.

Abstract: A system to remotely report the load condition of a railroad car including a mechanism to sense the load condition in the form of a switch responsive to load condition to change the state of an electrical circuit, a controller to recognize the state of the circuit and a radio wave transmitter directed by the controller to report the condition to a remote receiver. Load is sensed by recognition of the distance between two components of the car, one which remains relatively fixed regardless of the weight of the car, the other which moves relative to the first component as the car weight changes.

Abstract: A system to report the position and/or measured conditions of a railroad car using satellite communication. The system includes a rechargeable power supply and communications unit incorporating one or more solar cells in combination with a rechargeable battery and further including a bank of ultracapacitors. The equivalent series resistance or “ESR” of the capacitor bank is substantially less than the ESR of the battery thereby allowing peak power demands to be filled by rapid dissipation of stored charge from the capacitor bank without substantial involvement of the battery under normal conditions.

Abstract: A composition comprising a functionalized water-soluble, cationic, thermosetting, cellulose reactive polymer with a doubly structured backbone that is the reaction product of: (a) a copolymerized (i) acrylamide component, (ii) cationic co-monomer component and (iii) at least one multifunctional crosslinking monomer component; and (b) a cellulose reactive agent component; such that the acrylamide component, the cationic co-monomer component, the multifunctional crosslinking monomer component, and the cellulose reactive agent component are in an amount sufficient amount to produce a polymer that imparts strength to a fibrous substrate when the polymer is added to paper stock during a papermaking process. The invention also relates to methods for making and using such a composition.

Abstract: A system for monitoring railroad cars comprising a hatch cover assembly including a cover body, a sensor, a wireless transmitter for transmitting data received from the sensor, a wireless receiver for receiving the data from the wireless transmitter, and a satellite transmitter for transmitting the data to a satellite. The wireless receiver and the satellite transmitter are attached to the hatch cover assembly. In one embodiment, the sensor is a pressure sensor having a sensing unit situated in the plenum of a vented hatch cover. In another embodiment, the sensor is an air flow sensor having a sensing unit situated in the plenum of a vented hatch cover. In another embodiment, the sensor is a chain tension sensor attached to a handbrake chain. In another embodiment, the sensor is a hatch cover position attached to the hatch cover assembly.

Abstract: Storage is provisioned. By a user interface hosted at a storage system, a user is allowed to affect a set of storage system configuration settings residing on the storage system. The set of storage system configuration settings has options for different levels of redundant array of independent disks (RAID) data protection. Based on the set of storage system configuration settings, the storage system is configured for RAID data protection.

Abstract: A vented hatch cover comprising a cover body, an intake filter element, a discharge filter element and a gasket. The cover body has a plurality of walls defining an air intake passage, an air discharge passage, and a plenum extending from the air intake passage to the air discharge passage. The cover body includes a plurality of ribs extending across the air intake passage. The intake filter element is disposed over the air intake passage and includes a plurality of latches engaging the ribs to secure the intake filter element to the cover body. The cover body further includes an inner rim and an outer rim located radially outward of the inner rim. The inner rim and the outer rim define a pocket. The gasket is retained in the pocket of the cover body. The discharge filter element is disposed over the air discharge passage and includes a plurality of upward extending portions or latches located radially between the inner rim and the gasket.

Abstract: A system to remotely report the load condition of a railroad car including a mechanism to sense the load condition in the form of a switch responsive to load condition to change the state of an electrical circuit, a controller to recognize the state of the circuit and a radio wave transmitter directed by the controller to report the condition to a remote receiver. Load is sensed by recognition of the distance between two components of the car, one which remains relatively fixed regardless of the weight of the car, the other which moves relative to the first component as the car weight changes.

Abstract: A clamp assembly for connecting the end of a first pipe to the end of an axially aligned second pipe. The clamp assembly comprises a first semi-circular clamp arm, a second semi-circular clamp arm, a lever and a latch. The first clamp arm has a first end portion and a second end portion. The second clamp arm has a first end portion and a second end portion. The first end portion of the second clamp arm is pivotably attached to the first end portion of the first clamp arm. The lever is pivotably attached to the first end portion of the first clamp arm. The latch has a first end portion and a second end portion. The first end portion of the latch is pivotably attached the second end portion of the second clamp arm. The second end portion of the latch is attached to the lever upon the clamp assembly in a closed position. The distance between the attachment of the latch to the second clamp arm to the attachment of the latch to the lever is adjustable in the attachment of the latch to the second clamp arm.

Abstract: A clamp assembly for connecting the end of a first pipe to the end of an axially aligned second pipe. The clamp assembly comprises a first semi-circular clamp arm, a second semi-circular clamp arm, a lever, a latch and a gasket. The first clamp arm has a first end portion and a second end portion. The second clamp arm has a first end portion and a second end portion. The first end portion of the second clamp arm is pivotably attached to the first end portion of the first clamp arm. The lever is pivotably attached to the second portion of the first clamp arm. The latch has a first end portion and a second end portion. The first end portion of the latch is pivotably attached the second end portion of the second clamp arm. The second end portion of the latch is attached to the lever upon the clamp assembly in a closed position. The first clamp arm defines a groove for seating the gasket. The second clamp arm defines a groove for seating the gasket.