Patents by Inventor Michael Saunders
Michael Saunders has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240150739Abstract: The present disclosure relates generally to a polypeptide having mono-(2-hydroxyethyl) terephthalate hydrolase (MHETase) activity, more specifically to a polypeptide comprising an amino acid sequence that (i) has at least 70% sequence identity to SEQ ID NO:1 and (ii) differs from SEQ ID NO:1 by an amino acid substitution at one or more positions selected from the group consisting of positions that correspond to amino acid positions 156 to 396, 398 to 410 and 425 to 603 of SEQ ID NO:1.Type: ApplicationFiled: November 13, 2023Publication date: May 9, 2024Inventors: Jake Wesley SAUNDERS, Matthew SPENCE, Vanessa VONGSOUTHI, Adam Michael DAMRY, Colin John JACKSON
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Publication number: 20240074539Abstract: A footwear article includes (a) an upper having a tongue opening at a front thereof; (b) a gusseted tongue including a tongue panel positioned over the tongue opening and a pair of gussets attaching laterally opposite sides of the tongue panel to the upper; (c) a pair of tongue fasteners configured to selectively fasten and unfasten corresponding sides of the tongue panel to and from the upper; (d) a first lacing system on the upper and arranged for guiding lacing over the gusseted tongue and tongue fasteners when the sides of the tongue are fastened to the upper; and (e) a second lacing system on the tongue panel and arranged for guiding the lacing across the tongue panel clear of the tongue fasteners when the sides of the tongue panel are unfastened from the upper.Type: ApplicationFiled: November 9, 2023Publication date: March 7, 2024Inventors: Christopher Anderson, Adam Meek, Oliver Saunders, Michael Edward Blackford
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Patent number: 11920166Abstract: Described herein are variant, novel cannabinoid synthases, nucleic acids encoding same, and various uses thereof.Type: GrantFiled: July 20, 2022Date of Patent: March 5, 2024Assignee: RENEW BIOPHARMA, INC.Inventors: Kyle Botsch, Craig Behnke, Karla Gonzalez, Matthew Saunders, Michael Mendez
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Publication number: 20240026010Abstract: The present invention relates to antagonists, particularly antibodies and antigen binding fragments thereof, that bind to the protein galectin-10, particularly human galectin-10. The galectin-10 antagonists disrupt the crystallization of galectin-10 and are therefore useful in methods of preventing and treating diseases and conditions wherein the pathology is linked to the formation/presence of Charcot-Leyden crystals (CLCs).Type: ApplicationFiled: June 7, 2023Publication date: January 25, 2024Inventors: Jean-Michel PERCIER, Christophe Blanchetot, Michael Saunders, Hans De Haard, Sebastian Van Der Woning, Emma Persson, Bart Lambrecht, Savvas Savvides, Hamida Hammad, Kenneth Verstraete
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Patent number: 11874031Abstract: A system may include a first compressor, a second compressor, a first heat exchanger and a second heat exchanger. The first compressor has a first inlet and a first outlet. The second compressor is a sumpless compressor and has a second inlet and a second outlet. The second compressor provides working fluid discharged from the second outlet to the first compressor. The first heat exchanger is disposed upstream of the second compressor and provides working fluid to the second compressor. The second heat exchanger is disposed upstream of the first compressor and provides working fluid to the first compressor.Type: GrantFiled: December 18, 2019Date of Patent: January 16, 2024Assignee: Copeland LPInventors: Michael A. Saunders, Natarajan Rajendran, Michael M. Perevozchikov, Kirill M. Ignatiev
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Publication number: 20230368987Abstract: A DC disconnector comprising a static electrical contact, at least one moveable electrical contact comprising a plurality of conductor blades, and a shaft, coupled to the movable electrical contact. The shaft is configured to actuate the moveable electrical contact between a first configuration and a second configuration, wherein at least a portion of each conductor blade abuts the static electrical contact in the first configuration, and wherein the plurality of conductor blades are displaced from the static electrical contact in the second configuration.Type: ApplicationFiled: May 3, 2023Publication date: November 16, 2023Inventors: Stephen Hibberson, Michael Saunders, Christopher Hall
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Publication number: 20230263184Abstract: The present disclosure is directed to edible organogel compositions that comprise an organogelator and a flavor component, and processes for preparing the organogel compositions. The organogel compositions may be included as the flavor component in confectionery products, such as chewing gums.Type: ApplicationFiled: April 21, 2023Publication date: August 24, 2023Inventors: Armando J. CASTRO, Michael SAUNDERS
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Patent number: 11732916Abstract: A refrigerant control system includes: a charge module configured to determine an amount of refrigerant that is present within a first portion of a refrigeration system within a building; and an isolation module configured to selectively open and close an isolation valve of the refrigeration system and to, via the isolation valve, maintain the amount of refrigerant within the first portion within the building below a predetermined amount of the refrigerant.Type: GrantFiled: July 28, 2020Date of Patent: August 22, 2023Assignee: Emerson Climate Technologies, Inc.Inventors: Brian R. Butler, Stuart K. Morgan, Hung Pham, Winfield S. Morter, Andrew M. Welch, David Alfano, Michael A. Saunders
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Patent number: 11713893Abstract: A refrigerant control system includes: a charge module configured to determine an amount of refrigerant that is present within a refrigeration system of a building; a leak module configured to diagnose that a leak is present in the refrigeration system based on the amount of refrigerant; and at least one module configured to take at least one remedial action in response to the diagnosis that the leak is present in the refrigeration system.Type: GrantFiled: September 9, 2021Date of Patent: August 1, 2023Assignee: Emerson Climate Technologies, Inc.Inventors: Brian R. Butler, Stuart K. Morgan, Hung Pham, Winfield S. Morter, Andrew M. Welch, David A. Alfano, Michael A. Saunders
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Patent number: 11713354Abstract: The present invention relates to antagonists, particularly antibodies and antigen binding fragments thereof, that bind to the protein galectin-10, particularly human galectin-10. The galectin-10 antagonists disrupt the crystallization of galectin-10 and are therefore useful in methods of preventing and treating diseases and conditions wherein the pathology is linked to the formation/presence of Charcot-Leyden crystals (CLCs).Type: GrantFiled: March 8, 2021Date of Patent: August 1, 2023Assignees: ARGENX BV, VIB VZW, Universiteit GentInventors: Jean-Michel Percier, Christophe Blanchetot, Michael Saunders, Hans De Haard, Sebastian Van Der Woning, Emma Persson, Bart Lambrecht, Savvas Savvides, Hamida Hammad, Kenneth Verstraete
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Production of aspirin-triggered resolvins without the use of aspirin in a dietary omega-3 supplement
Patent number: 11707469Abstract: The present invention includes a composition and method of producing aspirin in situ, the method comprising: identifying a subject in need of aspirin or aspirin-like compounds; and providing the subject with a composition comprising: a source of methyl salicylate, an acetyl donor, and L-Arginine, wherein the composition is effective to produce aspirin-triggered resolvins in the subject without the deleterious effect of the aspirin or aspirin-like compounds in the stomach.Type: GrantFiled: March 19, 2020Date of Patent: July 25, 2023Assignee: Performance Labs Pte. Ltd.Inventors: Daniel Gubler, Michael Saunders -
Patent number: 11666066Abstract: The present disclosure is directed to edible organogel compositions that comprise an organogelator and a flavor component, and processes for preparing the organogel compositions. The organogelator is ethyl cellulose or a combination of ethyl cellulose and an edible wax, preferably candelilla wax, rice bran wax, carnauba wax, paraffin, beeswax, polyethylene wax or combinations thereof. The ethyl cellulose preferably has an average ethoxyl content of from 45.0% to 47.0% by weight of the ethyl cellulose or from 48.0% to 49.5% by weight of the ethyl cellulose. The organogel compositions may be included as the flavor component in confectionery products, such as chewing gums.Type: GrantFiled: November 9, 2018Date of Patent: June 6, 2023Assignee: WM. WRIGLEY JR. COMPANYInventors: Armando J. Castro, Michael Saunders
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Publication number: 20230088269Abstract: The present invention relates to antibodies and antigen binding fragments thereof which bind to the cytokine receptor IL-22R, particularly human IL-22R. The invention also relates to pharmaceutical compositions comprising said antibodies or antigen binding fragments thereof, and methods of treating psoriasis, psoriatic arthritis or atopic dermatitis.Type: ApplicationFiled: August 11, 2022Publication date: March 23, 2023Inventors: Christophe Frederic Jerome BLANCHETOT, Birgitte URSØ, Tine SKAK-NIELSEN, Malene BERTELSEN, Sebastian VAN DER WONING, Michael SAUNDERS, Johannes Joseph Wilhelmus DE HAARD
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Patent number: 11549730Abstract: A refrigerated food container system includes a container defining an inner volume and a thermoelectric module arranged in thermal contact with at least one surface of the container. The thermoelectric module includes a first thermoelectric cooling device and a second thermoelectric cooling device in thermal contact with the first thermoelectric cooling device. A control module is configured to provide a first voltage to the first thermoelectric cooling device and provide a second voltage to the second thermoelectric cooling device.Type: GrantFiled: January 31, 2020Date of Patent: January 10, 2023Assignee: Emerson Climate Technologies, Inc.Inventors: Jason A. Born, Damiel Faxon, Andrew Mangelsdorf, Michael A. Saunders
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Patent number: 11460224Abstract: Systems and methods for purging lubricant from a first compressor to a second compressor are provided. A control module receives a lubricant purge command, shuts the second compressor to an OFF-mode while the first compressor remains in the ON-mode, restricts working fluid from an outlet of the second compressor from flowing into the first compressor and allows compressed working fluid discharged from an outlet of the first compressor to flow into the inlet of the second compressor such that lubricant in the second compressor flows into the first compressor.Type: GrantFiled: October 30, 2019Date of Patent: October 4, 2022Assignee: Emerson Climate Technologies, Inc.Inventors: Michael A. Saunders, Kory M. Place, James Scott Fraser, Natarajan Rajendran, Jason A. Born, Daniel J. Rice
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Patent number: 11447544Abstract: The present invention relates to antibodies and antigen binding fragments thereof which bind to the cytokine receptor IL-22R, particularly human IL-22R. The invention also relates to pharmaceutical compositions comprising said antibodies or antigen binding fragments thereof, and methods of treating psoriasis, psoriatic arthritis or atopic dermatitis.Type: GrantFiled: October 23, 2019Date of Patent: September 20, 2022Assignee: argenx BVInventors: Christophe Frederic Jerome Blanchetot, Birgitte Ursø, Tine Skak-Nielsen, Malene Bertelsen, Sebastian Van Der Woning, Michael Saunders, Johannes Joseph Wilhelmus De Haard
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Publication number: 20220177604Abstract: The present invention relates to antibodies that bind to IgE and their use in the treatment of autoimmune diseases, particularly Bullous Pemphigoid (BP) and Chronic Spontaneous Urticaria (CSU). The anti-IgE antibodies comprise a variant Fc domain that binds to the Fc receptor FcRn with increased affinity relative to a wild-type Fc domain. The anti-IgE antibodies may comprise a variant Fc domain comprising the amino acids Y, T, E, K, F and Y at EU positions 252, 254, 256, 433, 434 and 436, respectively, wherein the variant Fc domain binds to human FcRn with increased affinity relative to a wild-type human IgG Fc domain.Type: ApplicationFiled: April 9, 2020Publication date: June 9, 2022Inventors: Michael SAUNDERS, Rene BIGIRIMANA, Christophe BLANCHETOT, Marijn CROMHEECKE, Conor MCGUIRE
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Patent number: 11261246Abstract: The present invention relates to antibodies and antigen binding fragments thereof which bind to the cytokine receptor IL-22R, particularly human IL-22R. The invention also relates to pharmaceutical compositions comprising said antibodies or antigen binding fragments thereof, and methods of treating psoriasis, psoriatic arthritis or atopic dermatitis.Type: GrantFiled: October 23, 2019Date of Patent: March 1, 2022Assignee: argenx BVInventors: Christophe Frederic Jerome Blanchetot, Birgitte Ursø, Tine Skak-Nielsen, Malene Bertelsen, Sebastian Van Der Woning, Michael Saunders, Johannes Joseph Wilhelmus De Haard
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Publication number: 20220030032Abstract: A generic endpoint package includes a generic node configuration, which can be used by all nodes within a network, containing consolidated configuration information regardless of the operating system, the generic node configuration including: node property sets; common information containing rules to apply to nodes while in service mode and prior to authorization; and registration information directing the node to a pre-defined registration servers. A method of using a generic endpoint package includes deploying the generic endpoint package having a generic node configuration, which can be used by all nodes within a network, containing consolidated configuration information regardless of the operating system, the generic node configuration including: node property sets; common information containing rules to apply to nodes while in service mode and prior to authorization; and registration information directing the node to a pre-defined registration servers.Type: ApplicationFiled: July 27, 2021Publication date: January 27, 2022Applicant: Unisys CorporationInventors: Jared Poetter, Michael C. Leap, Diane E. Schaefer, Michael J. Di Domenico, Philippe Jolly, Richard W. Phelps, Robert A. Johnson, Michael Saunders, Robert R. Buckwalter, Sarah K. Inforzato, Eugene J. Gretter, George Karian
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Publication number: 20220029996Abstract: A network model includes nodes, node property sets, authorization groups and authorization servers. The node property sets define how the nodes operate and authenticate. The nodes are member of the node property sets. The authorization groups are associated with the node property set. And, authorization servers are member of the authorization groups. In addition, a network model in a secure network environment has at least one community of interest. The network model includes at least one node being a member of a node property set that defines how the node operates and authenticates.Type: ApplicationFiled: July 27, 2021Publication date: January 27, 2022Applicant: Unisys CorporationInventors: Jared Poetter, Michael C. Leap, Diane E. Schaefer, Michael J. Di Domenico, Philippe Jolly, Richard W. Phelps, Robert A.` Johnson, Michael Saunders, Robert R. Buckwalter, Sarah K. Inforzato, Eugene J. Gretter, George Karian