Abstract: Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand.

Abstract: Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand.

Abstract: Methodologies, systems, apparatus, and non-transitory computer-readable media are described herein to facilitate acquisition of volumetric data and volumetric image reconstruction. An imaging system can be configured to transport an object at a speed relative to the scan path of an X-ray source such that insufficient measurement data is collected for classically complete geometrical coverage. Iterative image reconstruction techniques may be used to generate volumetric images based on measured volumetric data of at least a portion of the object.

Abstract: A brush head (32) including a neck (40) having a brush neck (42); a plurality of bristle tufts (21), each of which includes a plurality of bristle strands with a free end (25) and a proximal end (23), the proximal end having a proximal end head portion (26); a plurality of retention rings (50), each configured to receive the proximal end of at least one of the plurality of bristle tufts; an elastomeric matrix (30) bonded to at least a portion of the brush neck, the plurality of retention rings, and the proximal end of the plurality of bristle tufts, wherein the proximal end head portion of each of the plurality of bristle tufts is configured to comprise a space (27) between the proximal end head portion and the respective retention ring.

Abstract: Methods and apparatus are described for scoring documents in response, in part, to parameters related to the document, source, and/or cluster score. Methods and apparatus are also described for scoring a cluster in response, in part, to parameters related to documents within the cluster and/or sources corresponding to the documents within the cluster. In one embodiment, the invention may identify the source; detect a plurality of documents published by the source; analyze the plurality of documents with respect to at least one parameter, and determine a source score for the source in response, in part, to the parameter. In another embodiment, the invention may identify a topic; identify a plurality of clusters in response to the topic; analyze at least one parameter corresponding to each of the plurality of clusters; and calculate a cluster score for each of the plurality of clusters in response, in part, to the parameter.

Abstract: A system and a method for detecting a replacement component of a device. The method includes detecting a first identifier of a device which includes at least one replaceable component, using a mobile terminal; detecting a second identifier of at least one replacement component, using the mobile terminal; transmitting the detected first and second identifiers to a computing device; generating a control signal based on the first and second identifiers; transmitting the generated control signal to the device; and controlling the device with the aid of the control signal.

Abstract: A device for exerting torque on an object includes: at least one rotating mass rotatably supported about an axis of rotation; a drive for driving the rotating mass; a bearing which enables a change in the alignment of the axis of rotation relative to the object; and a coupling unit which engages on the bearing and couples the rotating mass to the object.

Abstract: Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand.

Abstract: Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand.

Abstract: A memory system includes a two memory modules and a memory controller. The memory modules each include at least a first memory package corresponding to a first number of memory ranks (e.g. one memory rank) and a second memory package corresponding to a second number of memory ranks (e.g. two memory ranks) that is greater than the first number of memory ranks. For each module, the memory packages may be asymmetrically staggered such that one memory package is further from the memory controller than the other memory package. The memory controller is coupled to the memory packages of both modules via a common data line and generates control information for controlling the on-die termination (ODT) of the memory packages.

Abstract: A container including a shoulder portion terminating at an opening and a sidewall portion extending from the shoulder portion to a base portion. The base portion closes off an end of the container. The shoulder portion, the sidewall portion and the base portion cooperate to define a receptacle chamber within the container into which product can be filled. A barrier layer extends continuously along the base portion, the sidewall portion, and the shoulder portion to the opening and is made of a polymer based material.

Abstract: A system and a method for detecting a replacement component of a device. The method includes detecting a first identifier of a device which includes at least one replaceable component, using a mobile terminal; detecting a second identifier of at least one replacement component, using the mobile terminal; transmitting the detected first and second identifiers to a computing device; generating a control signal based on the first and second identifiers; transmitting the generated control signal to the device; and controlling the device with the aid of the control signal.

Abstract: A system identifies a first document that includes a number of first images, identifies a second document that includes a number of second images, and forms a cluster based on a relationship between the first document and the second document. The system identifies a first caption associated with one of the first images, identifies a second caption associated with one of the second images, selects the one of the first images or the one of the second images as a representative image for the cluster based on the first caption or the second caption, and associates the representative image with the cluster.

Abstract: Methods and apparatus are described for scoring documents in response, in part, to parameters related to the document, source, and/or cluster score. Methods and apparatus are also described for scoring a cluster in response, in part, to parameters related to documents within the cluster and/or sources corresponding to the documents within the cluster. In one embodiment, the invention may detect at least one document within the cluster; analyze a parameter corresponding to the document; and compute a cluster score based, in part, on the parameter, wherein the cluster score corresponds with at least one document within the cluster.

Abstract: Systems and method for calculating energy expenditure values and activity points are provided. One or more devices may use an accelerometer and/or other sensors to monitor activity of a user. The user may identify the activity via one of the devices, a mobile phone, a computer device or another device. Activity points or energy expenditure values may be calculated from data received from sensors and the identification provided by the user.

Abstract: Methods and apparatus are described for scoring documents in response, in part, to parameters related to the document, source, and/or cluster score. Methods and apparatus are also described for scoring a cluster in response, in part, to parameters related to documents within the cluster and/or sources corresponding to the documents within the cluster. In one embodiment, the invention may identify the source; detect a plurality of documents published by the source; analyze the plurality of documents with respect to at least one parameter; and determine a source score for the source in response, in part, to the parameter. In another embodiment, the invention may identify a topic; identify a plurality of clusters in response to the topic; analyze at least one parameter corresponding to each of the plurality of clusters; and calculate a cluster score for each of the plurality of clusters in response, in part, to the parameter.

Abstract: A first and second set of simulation information of a circuit design may be received. Energy consumption values associated with signals may be calculated for each of the first and second sets of simulation information of the circuit design. The energy consumption values associated with the transitions of the plurality of signals for each time point of a plurality of time points may be aggregated based on when each of the transitions of the signals occurs for each of the first and second sets of simulation information. Furthermore, a possible Differential Power Analysis (DPA) leak may be identified at one of the time points based on a difference in aggregated energy consumption values between the first and second sets of simulation information.

Abstract: A news aggregation server aggregates and monetizes restricted news content. The news aggregation server fetches the restricted news content from multiple news source servers that are remote from the news aggregation server. The news aggregation server aggregates the fetched restricted news content and searches the aggregated news content based on input received from a client. The news aggregation server provides access to selected news content from the aggregated news content that is relevant to the client input and charges the user a price for accessing the selected restricted news content.

Abstract: A system ranks results. The system may receive a list of links. The system may identify a source with which each of the links is associated and rank the list of links based at least in part on a quality of the identified sources.

Abstract: A memory system includes a two memory modules and a memory controller. The memory modules each include at least a first memory package corresponding to a first number of memory ranks (e.g. one memory rank) and a second memory package corresponding to a second number of memory ranks (e.g. two memory ranks) that is greater than the first number of memory ranks For each module, the memory packages may be asymmetrically staggered such that one memory package is further from the memory controller than the other memory package. The memory controller is coupled to the memory packages of both modules via a common data line and generates control information for controlling the on-die termination (ODT) of the memory packages.