Abstract: An apparatus and a method for controlling the output of driver information to a driver of a vehicle, with the objective of entertaining the driver and/or the passengers of the vehicle and/or increasing the driver attentiveness of the driver. A database of points of interest or objects of general interest, a database of topographic information, a device for determining the whereabouts of the vehicle, and an evaluation device to which these information items are delivered, are provided. The evaluation device ascertains, from the current whereabouts of the vehicle and from the topographic information, which points of interest or objects of general interest are present in the driver's field of view, and outputs via an output device the driver information regarding the point of interest or the object of general interest which has been ascertained by the evaluation device to be located in the driver's field of view.

Abstract: Systems for performing cellular analysis and related devices for conditioning environments adjacent chips in such systems. A device for conditioning an environment adjacent a chip in a system for performing cellular analysis, the device includes a cover for being disposed adjacent the chip and comprising a planar body having a top surface, a bottom surface, and an outer edge surface. The cover includes a central opening extending between the top surface and the bottom surface and bounded by an inner edge surface of the cover. The cover also includes a fluid inlet extending into the body from the outer edge surface between the top surface and the bottom surface the fluid inlet arranged to accept a gas to be delivered to the central opening. The cover also includes a plurality of fluid outlets defined in the inner edge surface and in fluid communication with the fluid inlet. The plurality of fluid outlets are arranged to receive the gas from the fluid inlet and exhaust the gas into the central opening.

Abstract: An optical element held in a holder has a first optical surface which has no rotational symmetry with regard to its imaging axis. The holder has at least one reference element, which defines a position and/or orientation of the holder in a predefined coordinate system which compensates for a difference between an actual pose of the first optical surface and a target pose of the first optical surface in the holder at least in one degree of freedom. The reference element defines at least one specific azimuthal position of the holder. Also provided is a method for adjusting the holder of an optical element that has at least a first optical surface, which has no rotational symmetry with regard to its imaging axis, to a difference between an actual pose of the first optical surface and a target pose of the first optical surface in the holder.

Abstract: A fiber support assembly includes: a first glass tube, wherein the first glass tube is at tached to a microlens or lenslet of a microlens or lenslet array; a second glass tube at least partially disposed within the first glass tube; and a gain fiber disposed within the second glass tube, wherein the gain fiber has a first tapered end cap, and wherein the gain fiber with the first tapered end cap is aligned to the microlens or lenslet attached to the first glass tube. The fiber support assembly may further include: a pump fiber disposed within the second glass tube, wherein the pump fiber has a second tapered end cap; and a reflector configured to receive counter-pumping light from the pump fiber and direct the counter-pumping light to the first tapered end cap of the gain fiber.

Abstract: An apparatus and a method for controlling the output of driver information to a driver of a vehicle, with the objective of entertaining the driver and/or the passengers of the vehicle and/or increasing the driver attentiveness of the driver. A database of points of interest or objects of general interest, a database of topographic information, a device for determining the whereabouts of the vehicle, and an evaluation device to which these information items are delivered, are provided. The evaluation device ascertains, from the current whereabouts of the vehicle and from the topographic information, which points of interest or objects of general interest are present in the driver's field of view, and outputs via an output device the driver information regarding the point of interest or the object of general interest which has been ascertained by the evaluation device to be located in the driver's field of view.

Abstract: An actuator for adjusting an element to be moved in a beam path of an optical arrangement contains the element to be moved, a carrier and at least one SM element, the SM element being connected to the element to be moved and designed such that it is supported on the carrier, so that when the dimension of the SM element changes, a directed force effect is produced between the element to be moved and the carrier.

Abstract: A method for operating a vehicle having a driver assistance system intervening in a transverse dynamics of the vehicle, comprising the steps: detecting a driver intervention in a driving behavior of the vehicle due to an intervention of at least one actuator triggered by the driver assistance system; interpreting the driver intervention as an override of the intervention of the actuator; and reducing in a defined manner the intervention of the actuator as a function of the interpretation of the driver intervention in such a way that a driving task is returned to the driver in a controlled and defined manner.

Abstract: A purification system and method may include a container receiving portion, pump, and magnetic field generating element. The container receiving portion may be configured to receive and support a container containing a mixture. Magnetic beads may be added to the container for separating a target substance from a remainder of the mixture. The magnetic field generating element may be movable relative to the container receiving portion between a non-working position remote from the container receiving portion and a working position adjacent an outer periphery of the container receiving portion. In the working position, the magnetic field generating element may attract the magnetic beads and hold them firmly against an interior surface of the container. While the magnetic beads are immobilized by the magnetic field generating element, the pump may remove the mixture from the container, leaving behind the magnetic beads bound tightly but reversibly to the target substance.

Abstract: A purification system and method may include a container receiving portion, pump, and magnetic field generating element. The container receiving portion may be configured to receive and support a container containing a mixture. Magnetic beads may be added to the container for separating a target substance from a remainder of the mixture. The magnetic field generating element may be movable relative to the container receiving portion between a non-working position remote from the container receiving portion and a working position adjacent an outer periphery of the container receiving portion. In the working position, the magnetic field generating element may attract the magnetic beads and hold them firmly against an interior surface of the container. While the magnetic beads are immobilized by the magnetic field generating element, the pump may remove the mixture from the container, leaving behind the magnetic beads bound tightly but reversibly to the target substance.

Abstract: Computer-implemented methods of enabling an on-the-fly generation of at least one user-defined montage from EEG electrodes positioned in a patient's brain, on the patient's brain and/or on the patient's scalp. The methods includes generating a graphical interface to display a view of the patient's brain and/or scalp overlaid with the EEG electrodes, each of which is uniquely identified with reference to its position in the patient's brain, on the patient's brain and/or on the patient's scalp, displaying a tool within the graphical interface for selecting at least one electrode from the displayed EEG electrodes, indicating a reference electrode corresponding to the selected electrode, accessing EEG signals corresponding to the electrode and the reference electrode, and generating another graphical interface to display an EEG trace indicative of a comparison of EEG signals of the electrode and the reference electrode.

Abstract: A method and device for the optical scanning of a chromatographic sample (3), where a sample plate (2) holding the sample (3) is illuminated with light from a first illumination device (13) and the light emitted by the sample plate (2) is detected by an optical detector device (15) which detects in cell form or area form, a second illumination device (14) is preferably firstly activated in a preparation step. The sample plate (2) is displaced in a first displacement direction relative to the detector device (15), illuminated by the first illumination device (13) and a first measurement image is recorded. The sample plate (2) is displaced in a second displacement direction relative to the detector device (15), illuminated by the second illumination device (14), and a second measurement image is recorded.

Abstract: The present invention is directed to a process for producing inorganic particulate material, the material obtainable by such process, a modified release delivery system comprising the material and the use of the material for the administration of a bioactive agent.

Abstract: Method and apparatus for the electrodeposition of a contact metal layer on contact areas of semiconductor components in a wafer assemblage. The method comprises: a) providing a wafer having components having at least one pn junction; b) arranging a non-conductive homogenizing device with respect to the first surfaces of the components, and an electrical contact device at a second surface of the wafer; c) introducing the wafer into an electroplating bath having an electrode, wherein the surface thereof consists at least partly of a first contact metal, and wherein the first surface of the components is in contact with the electroplating bath; d) applying a voltage to the electrode and to the contact device, as a result of which current flows between the electrode and the contact device, through the electroplating bath and the component and contact metal is thus deposited at the first contact areas of the components.

Abstract: Compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R1, R2 and R3 are as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by positive allosteric modulation of the ?-aminobutyric acid B (GABA-B) receptor. Methods for making the compounds are described. Also described are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions.

Abstract: Compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein R1, R2 and R3 are as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by positive allosteric modulation of the ?-aminobutyric acid B (GABA-B) receptor. Methods for making the compounds are described. Also described are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions.

Abstract: An annular clamping nut which is provided for being placed onto the end of a tie bar, in order to brace the latter, and which has in addition to a central recess for receiving the tie bar parallel to a longitudinal direction passages at uniform radial spacings in the ring circumferential direction which are directed parallel to the longitudinal direction of the central recess and are provided for receiving clamping screws. An external thread is provided on the outer surface of the clamping nut, which outer surface is arranged on a side which lies substantially opposite the wall of the central recess, which external thread runs substantially in the ring circumferential direction of the outer surface.

Abstract: An actuator for adjusting an element to be moved in a beam path of an optical arrangement contains the element to be moved, a carrier and at least one SM element, the SM element being connected to the element to be moved and designed such that it is supported on the carrier, so that when the dimension of the SM element changes, a directed force effect is produced between the element to be moved and the carrier.

Abstract: A purification system and method may include a container receiving portion, pump, and magnetic field generating element. The container receiving portion may be configured to receive and support a container containing a mixture. Magnetic beads may be added to the container for separating a target substance from a remainder of the mixture. The magnetic field generating element may be movable relative to the container receiving portion between a non-working position remote from the container receiving portion and a working position adjacent an outer periphery of the container receiving portion. In the working position, the magnetic field generating element may attract the magnetic beads and hold them firmly against an interior surface of the container. While the magnetic beads are immobilized by the magnetic field generating element, the pump may remove the mixture from the container, leaving behind the magnetic beads bound tightly but reversibly to the target substance.

Abstract: A method for operating a vehicle having a driver assistance system intervening in a transverse dynamics of the vehicle, comprising the steps: detecting a driver intervention in a driving behavior of the vehicle due to an intervention of at least one actuator triggered by the driver assistance system; interpreting the driver intervention as an override of the intervention of the actuator; and reducing in a defined manner the intervention of the actuator as a function of the interpretation of the driver intervention in such a way that a driving task is returned to the driver in a controlled and defined manner.

Abstract: A semiconductor diode includes a semiconductor body, having a first main area formed from an inner area, on which a first contact layer is arranged, and from an edge area, a current path from the first contact layer to a second contact layer arranged on a second main area situated opposite the first main area, wherein the semiconductor diode, by virtue of the configuration of the first contact layer or of the semiconductor body, is formed such that upon current flow, such current flows through a current path having the greatest heating per unit volume, and which proceeds from a further partial area of the inner area, wherein the further partial area is arranged on the other side of a boundary of an inner partial area of the inner area, said inner partial area preferably being arranged centrally, with respect to an outer partial area adjoining said inner partial area.