Abstract: Porous and microporous parts prepared by additive manufacturing as disclosed herein are useful in medical and non-medical applications. The parts are prepared from a composition containing both a solvent soluble component and a solvent insoluble component. After a part is printed by an additive manufacturing process it is exposed to solvent to extract solvent soluble component away front the printed part, resulting in a part having surface cavities.

Abstract: Thermally stable absorbable fiber populations, i.e. fiber populations that do not undergo thermally induced crystallization, can be intermixed with thermally unstable fibers to yield a stabilizing effect without altering morphological properties of a fiber system. Via this, one may minimize thermally induced shrinkage and maintain physical properties of electrospun materials in the as-formed state.

Abstract: Thermally stable absorbable fiber populations, i.e. fiber populations that do not undergo thermally induced crystallization, can be intermixed to yield a stabilizing effect without altering morphological properties of a first fiber system. By addition of a stabilizing fiber population one may minimize thermally induced shrinkage and maintain physical properties of electrospun materials in the as-formed state. In one particular abstract, medical barrier materials may be formed from the electrospun materials to provide improved medical barriers for treatments.

Abstract: Porous and microporous parts prepared by additive manufacturing as disclosed herein are useful in medical and non-medical applications. The parts are prepared from a composition containing both a solvent soluble component and a solvent insoluble component. After a part is printed by an additive manufacturing process it is exposed to solvent to extract solvent soluble component away from the printed part, resulting in a part having surface cavities.

Abstract: A composite implant device for use in a medical application, comprising a synthetically-derived mesh that mimics particular critical aspects of a biologically-derived mesh. The composite implant device can be used for the reinforcement and reconstruction of tissues within the body and can be comprised of a majority of synthetic components and minority of naturally-derived components which mimic the structure and function of a naturally-derived mesh.

Abstract: Thermally stable absorbable fiber populations, i.e. fiber populations that do not undergo thermally induced crystallization, can be intermixed to yield a stabilizing effect without altering morphological properties of a first fiber system. By addition of a stabilizing fiber population one may minimize thermally induced shrinkage and maintain physical properties of electrospun materials in the as-formed state. In one particular abstract, medical barrier materials may be formed from the electrospun materials to provide improved medical barriers for treatments.

Abstract: Medical implants that include a containment layer surrounding, or surrounded by, a biodegradable medical device provide the benefit that pieces formed during degradation of the medical device are held within a constrained place and thus do not causes injury to a hosts.

Abstract: Thermally stable absorbable fiber populations, i.e. fiber populations that do not undergo thermally induced crystallization, can be intermixed with thermally unstable fibers to yield a stabilizing effect without altering morphological properties of a fiber system. Via this, one may minimize thermally induced shrinkage and maintain physical properties of electrospun materials in the as-formed state.

Abstract: Porous and microporous parts prepared by additive manufacturing as disclosed herein are useful in medical and non-medical applications. The parts are prepared from a composition containing both a solvent soluble component and a solvent insoluble component. After a part is printed by an additive manufacturing process it is exposed to solvent to extract solvent soluble component away from the printed part, resulting in a part having surface cavities.

Abstract: Disclosed herein polylactide polymer blend compositions, and methods of making and using such compositions.

Abstract: Porous and microporous parts prepared by additive manufacturing as disclosed herein are useful in medical and non-medical applications. The parts are prepared from a composition containing both a solvent soluble component and a solvent insoluble component. After a part is printed by an additive manufacturing process it is exposed to solvent to extract solvent soluble component away from the printed part, resulting in a part having surface cavities.

Abstract: A composite implant device for use in a medical application, comprising a synthetically-derived mesh that mimics particular critical aspects of a biologically-derived mesh. The composite implant device can be used for the reinforcement and reconstruction of tissues within the body and can be comprised of a majority of synthetic components and minority of naturally-derived components which mimic the structure and function of a naturally-derived mesh.

Abstract: Disclosed herein are contraceptive medical devices that include at least a polymeric ring, a porous barrier material and an injection molding guide, where the guide may be symmetrical and/or have one or a plurality of planar surfaces, where the device may optionally administer at least one active agent.

Abstract: Thermally stable absorbable fiber populations, i.e. fiber populations that do not undergo thermally induced crystallization, can be intermixed with thermally unstable fibers to yield a stabilizing effect without altering morphological properties of a fiber system. Via this, one may minimize thermally induced shrinkage and maintain physical properties of electrospun materials in the as-formed state.

Abstract: Medical implants that include a containment layer surrounding, or surrounded by, a biodegradable medical device provide the benefit that pieces formed during degradation of the medical device are held within a constrained place and thus do not causes injury to a hosts.

Abstract: Disclosed herein are methods, devices and compositions for degradable medical devices and/or compositions that provide local and/or systemic delivery of at least one active agent.

Abstract: In situ gel-forming compositions are disclosed, which may comprise one or more absorbable polymers, solvents such as N-methyl-2-pyrrolidone, polyethylene glycol or DMSO, and one or more bioactive agents. The composition forms a hydrogel or semi-solid mass on contact with an aqueous environment.

Abstract: Disclosed herein are methods of making and using compositions comprising medical devices, particularly medical devices made from resorbable polymers.

Abstract: Polymers and formulated compositions are designed to have properties that allow their effective use in additive manufacturing processes, particularly for preparing articles wherein molten monofilament polymer is laid down on top of a previously deposited line of molten monofilament polymer.

Abstract: A biodegradable nasal splint comprising a tubular component at least partially defining a hollow passageway. The tubular component may be formed from a degradable material comprising a copolymer comprising glycolide subunits, trimethyl carbonate subunits, and caprolactone subunits. The degradable material may further comprise from about 0.01% to about 30% chitosan, by weight of the degradable material. The biodegradable nasal splint may further comprise a therapeutic agent such as chitosan applied to one or more surfaces of the nasal splint Also, a biodegradable nasal splint comprising a tubular component at least partially defining a hollow passageway and formed from a degradable material. The degradable material may comprise at least about 95% chitosan, by weight of the degradable material.