Patents by Inventor Michael Speicher

Michael Speicher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20050266237
    Abstract: A heat-activated sound and vibration damping sealant composition is provided. The composition includes dried automotive paint powder and an unsaturated polymer, where the paint powder reacts with the unsaturated polymer when the composition is heated to greater than 200° F. (80° C.). Upon heating, composition expands and increases in tensile strength. The composition may be provided in the form of a tape which is adhered to a substrate such as an automotive or appliance part and then exposed to elevated temperatures such as those encountered in automotive, appliance, or other commercial paint bake processes. Thereafter, the composition provides sound and vibration damping properties.
    Type: Application
    Filed: May 28, 2004
    Publication date: December 1, 2005
    Inventors: Siddhartha Asthana, Michael Speicher
  • Publication number: 20030235840
    Abstract: The invention relates to a set of combinatorially labeled oligonucleotide probes each member thereof: (i) having a predetermined label distinguishable from the label of any other member of said set, and (ii) being capable of specifically hybridizing with a predetermined chromosome or nucleic acid molecule, and to the use of such molecules, alone or in concert with nucleic acid amplification methods.
    Type: Application
    Filed: January 24, 2003
    Publication date: December 25, 2003
    Inventors: David C. Ward, Michael Speicher, Stephen Gwyn Ballard
  • Publication number: 20030157537
    Abstract: A method of determining the relative number of nucleic acid sequences in test cells which provides for a high resolution during comparative genomic hybridization by keeping all components separate from each other and selecting target nucleic acids which have a high resolution capability for determining genomic imbalances in the test cells and which facilitate a screening of the test cells for over- or under-expression of individual genes.
    Type: Application
    Filed: December 30, 2002
    Publication date: August 21, 2003
    Inventors: Thomas Cremer, Thomas Ried, Michael Speicher, Anna Jauch, Peter Lichter
  • Patent number: 6548259
    Abstract: The invention relates to a set of combinatorially labeled oligonucleotide probes each member thereof: (i) having a predetermined label distinguishable from the label of any other member of said set, and (ii) being capable of specifically hybridizing with a predetermined chromosome or nucleic acid molecule, and to the use of such molecules, alone or in concert with nucleic acid amplification methods.
    Type: Grant
    Filed: November 20, 2001
    Date of Patent: April 15, 2003
    Assignee: Yale University
    Inventors: David C. Ward, Michael Speicher, Stephen Gwyn Ballard, John T. Wilson
  • Publication number: 20030027159
    Abstract: The invention relates to a set of combinatorially labeled oligonucleotide probes each member thereof: (i) having a predetermined label distinguishable from the label of any other member of said set, and (ii) being capable of specifically hybridizing with a predetermined chromosome or nucleic acid molecule, and to the use of such molecules, alone or in concert with nucleic acid amplification methods.
    Type: Application
    Filed: November 20, 2001
    Publication date: February 6, 2003
    Inventors: David C. Ward, Michael Speicher, Stephen Gwyn Ballard, John T. Wilson
  • Patent number: 6506563
    Abstract: The invention relates to a set of combinatorially labeled oligonucleotide probes each member thereof: (i) having a predetermined label distinguishable from the label of any other member of said set, and (ii) being capable of specifically hybridizing with a predetermined chromosome or nucleic acid molecule, and to the use of such molecules, alone or in concert with nucleic acid amplification methods.
    Type: Grant
    Filed: December 22, 1999
    Date of Patent: January 14, 2003
    Assignee: Yale University
    Inventors: David C. Ward, Michael Speicher, Stephen Gwyn Ballard
  • Patent number: 6484978
    Abstract: An apparatus for the support of a cardan shaft within a gimbal ball includes a pair of cardan support cranes that are adapted to pivot around an inner elevation axis in the ball and which each support one of a pair of vibration isolators. Each end of the cardan shaft is supported by one of the vibration isolators. An outer elevation drive motor is attached to the ball and drives against a bevel section of a combination bevel sector and spur gear that is attached to an outer support structure, that supports the ball. The motor drives the ball in elevation relative to the outer support structure. This causes the ball to rotate relative to the bevel sector and spur gear.
    Type: Grant
    Filed: April 18, 2001
    Date of Patent: November 26, 2002
    Inventors: Che Ram Souza Voigt, Allan Alfred Voigt, John Michael Speicher
  • Publication number: 20010036633
    Abstract: A method of determining the relative number of nucleic acid sequences in test cells which provides for a high resolution during comparative genomic hybridization by keeping all components separate from each other and selecting target nucleic acids which have a high resolution capability for determining genomic imbalances in the test cells and which facilitate a screening of the test cells for over- or under-expression of individual genes.
    Type: Application
    Filed: January 31, 2001
    Publication date: November 1, 2001
    Inventors: Thomas Cremer, Thomas Ried, Michael Speicher, Anna Jauch, Peter Lichter
  • Patent number: 6197501
    Abstract: A method of determining the relative number of nucleic acid sequences in test cells which provides for a high resolution during comparative genomic hybridization by keeping all components separate from each other and selecting target nucleic acids which have a high resolution capability for determining genomic imbalances in the test cells and which facilitate a screening of the test cells for over- or under-expression of individual genes.
    Type: Grant
    Filed: June 24, 1996
    Date of Patent: March 6, 2001
    Assignee: Deutsches Krebsforschungszentrum
    Inventors: Thomas Cremer, Thomas Ried, Michael Speicher, Anna Jauch, Peter Lichter
  • Patent number: 6007994
    Abstract: The invention relates to a set of combinatorially labeled oligonucleotide probes each member thereof: (i) having a predetermined label distinguishable from the label of any other member of said set, and (ii) being capable of specifically hybridizing with a predetermined chromosome or nucleic acid molecule, and to the use of such molecules, alone or in concert with nucleic acid amplification methods.
    Type: Grant
    Filed: June 2, 1998
    Date of Patent: December 28, 1999
    Assignee: Yale University
    Inventors: David C. Ward, Michael Speicher, Stephen Gwyn Ballard, John T. Wilson
  • Patent number: 5759781
    Abstract: The invention relates to a set of combinatorially labeled oligonucleotide probes each member thereof: (i) having a predetermined label distinguishable from the label of any other member of said set, and (ii) being capable of specifically hybridizing with one predetermined autosomal or sex chromosome of a human karyotype, and to the use of such molecules to identify the individual autosomal and sex chromosomes of a human karyotype.
    Type: Grant
    Filed: May 1, 1996
    Date of Patent: June 2, 1998
    Assignee: Yale University
    Inventors: David C. Ward, Michael Speicher, Stephen Gwynn Ballard