Patents by Inventor Michael T. Black

Michael T. Black has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • spsA polynucleotides and polypeptides
    Publication number: 20020068069
    Abstract: spsA polypeptides and DNA (RNA) encoding such spsA and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such spsA for the treatment of infection, particularly bacterial infections. Antagonists against such spsA and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of spsA nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding spsA and for detecting the polypeptide in a host.
    Type: Application
    Filed: June 1, 2001
    Publication date: June 6, 2002
    Applicant: SmithKline Beecham Corporation
    Inventors: Michael T. Black, Karen M. O'Dwyer
  • Signal peptidase polypeptides of Staphylococcus aureus
    Patent number: 6300097
    Abstract: spsB polypeptides and DNA (RNA) encoding such spsB and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such spsB for the treatment of infection, particularly bacterial infections. Antagonists against such spsB and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of spsB nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding spsB and for detecting the polypeptide in a host.
    Type: Grant
    Filed: June 25, 1999
    Date of Patent: October 9, 2001
    Assignee: SmithKline Beecham PLC
    Inventors: Michael T. Black, Karen M. O'Dwyer
  • Signal recognition particle polypeptides and polynucleotides
    Patent number: 6284515
    Abstract: This invention relates to a novel bacterial ribonucleoprotein complex and the component parts thereof. More specifically, this invention relates to SRP isolated from Staphylococcus aureus and the use of SRP or components thereof in screens for the identification of antimicrobial compounds and to the use of such compounds in therapy.
    Type: Grant
    Filed: March 5, 1998
    Date of Patent: September 4, 2001
    Assignee: SmithKline Beecham Corporation
    Inventor: Michael T. Black
  • spsA polynucleotides
    Patent number: 6255072
    Abstract: spsA polypeptides and DNA (RNA) encoding such spsA and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such spsA for the treatment of infection, particularly bacterial infections. Antagonists against such spsA and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of spsA nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding spsA and for detecting the polypeptide in a host.
    Type: Grant
    Filed: September 30, 1997
    Date of Patent: July 3, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Michael T. Black, Karen M. O'Dwyer
  • Vectors carrying coding sequence for the SpsB protein of Staphylococcus aureus
    Patent number: 5977085
    Abstract: spsB polypeptides and DNA (RNA) encoding such spsB and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such spsB for the treatment of infection, particularly bacterial infections. Antagonists against such spsB and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of spsB nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding spsB and for detecting the polypeptide in a host.
    Type: Grant
    Filed: September 30, 1997
    Date of Patent: November 2, 1999
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Michael T. Black, Karen M. O'Dwyer