Abstract: A vascular guiding catheter comprises an inner tubular member having a torque transmitting member formed over a major portion thereof and a soft polymeric tip formed at the distal end thereof. The torque transmitting member provides the characteristics of torsional stiffness and axial flexibility which are necessary to be able to introduce the catheter to the vascular system. The soft polymeric tip reduces the likelihood that the catheter can injure the blood vessel and provides a convenient location for the inclusion of perfusion ports. A reinforcement layer is provided over a transition region between the termination of the torque transmitting member and the soft distal tip. Optionally, reinforcement layers may be provided elsewhere along the length of the catheter.