Patents by Inventor Michael Urquhart

Michael Urquhart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline forms of (3R, 6R)-3-(2,3-dihydro-1H-inden-2-yl)-1-[(1R)-1-(2,6-dimethyl-3-pyridinyl)-2-(4-morpholinyl)-2-oxoethyl]-6-[(1S)-1-methylpropyl]-2,5-piperazinedione
    Patent number: 8815856
    Abstract: Disclosed are crystalline forms of (3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)-1-[(1R)-1-(2,6-dimethyl-3-pyridinyl)-2-(4-morpholinyl)-2-oxoethyl]-6-[(1S)-1-methylpropyl]-2,5-piperazinedione benzenesulfonate salt and pharmaceutical compositions thereof. Also disclosed are processes for the preparation the above compounds and methods for use thereof.
    Type: Grant
    Filed: March 18, 2014
    Date of Patent: August 26, 2014
    Assignee: Glaxo Group Limited
    Inventors: Richard Bellingham, Andrew Mark Buswell, Victoria Ironmonger, Michael Urquhart
  • NOVEL CRYSTALLINE FORMS OF (3R, 6R)-3-(2,3-DIHYDRO-1H-INDEN-2-YL)-1-[(1R)-1-(2,6-DIMETHYL-3-PYRIDINYL)-2-(4-MORPHOLINYL)-2-OXOETHYL]-6-[(1S)-1-METHYLPROPYL]-2,5-PIPERAZINEDIONE
    Publication number: 20140200218
    Abstract: Disclosed are crystalline forms of (3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)-1-[(1R)-1-(2,6-dimethyl-3-pyridinyl)-2-(4-morpholinyl)-2-oxoethyl]-6-[(1S)-1-methylpropyl]-2,5-piperazinedione benzenesulfonate salt and pharmaceutical compositions thereof. Also disclosed are processes for the preparation the above compounds and methods for use thereof.
    Type: Application
    Filed: March 18, 2014
    Publication date: July 17, 2014
    Applicant: Glaxo Group Limited
    Inventors: Richard Bellingham, Andrew Mark Buswell, Victoria Ironmonger, Michael Urquhart
  • Crystalline forms of (3R, 6R)-3-(2,3-dihydro-1H-inden-2-yl)-1-[(1R)-1-(2,6-dimethyl-3-pyridinyl)-2-(4-morpholinyl)-2-oxoethyl]-6-[(1S)-1-methylpropyl]-2,5-piperazinedione
    Patent number: 8716286
    Abstract: The present invention relates to crystalline forms of (3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)-1-[(1R)-1-(2,6-dimethyl-3-pyridinyl)-2-(4-morpholinyl)-2-oxoethyl]-6-[(1S)-1-methylpropyl]-2,5-piperazinedione benzenesulfonate salt and pharmaceutical compositions thereof. Also disclosed are processes for the preparation the above compounds and methods for use thereof.
    Type: Grant
    Filed: October 28, 2010
    Date of Patent: May 6, 2014
    Assignee: Glaxo Group Limited
    Inventors: Richard Bellingham, Andrew Mark Buswell, Victoria Ironmonger, Michael Urquhart
  • Process for the preparation of atovaquone
    Patent number: 8598387
    Abstract: Disclosed herein is novel process for preparation of atovaquone, which process includes reacting 1H-2-benzopyran-1,4(3H)-dione with 4-(4-chlorophenyl)cyclohexanecarbaldehyde. The invention further discloses novel intermediates useful in the preparation of atovaquone.
    Type: Grant
    Filed: December 13, 2011
    Date of Patent: December 3, 2013
    Assignee: Glaxo Group Limited
    Inventors: Andrew Neil Dwyer, Andrew Gordon, Michael Urquhart
  • PROCESS FOR THE PREPARATION OF ATOVAQUONE
    Publication number: 20130267717
    Abstract: Disclosed herein is novel process for preparation of atovaquone, which process includes reacting 1H-2-benzopyran-1,4(3H)-dione with 4-(4-chlorophenyl)cyclohexanecarbaldehyde. The invention further discloses novel intermediates useful in the preparation of atovaquone.
    Type: Application
    Filed: December 13, 2011
    Publication date: October 10, 2013
    Applicant: GLAXO GROUP LIMITED
    Inventors: Andrew Neil Dwyer, Andrew Gordon, Michael Urquhart
  • NOVEL CRYSTALLINE FORMS OF (3R, 6R)-3-(2,3-DIHYDRO-1H-INDEN-2-YL)-1-[(1R)-1-(2,6-DIMETHYL-3-PYRIDINYL)-2-(4-MORPHOLINYL)-2-OXOETHYL]-6-[(1S)-1-METHYLPROPYL]-2,5-PIPERAZINEDIONE
    Publication number: 20130109690
    Abstract: The present invention relates to crystalline forms of (3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)-1-[(1R)-1-(2,6-dimethyl-3-pyridinyl)-2-(4-morpholinyl)-2-oxoethyl]-6-[(1S)-1-methylpropyl]-2,5-piperazinedione benzenesulfonate salt and pharmaceutical compositions thereof. Also disclosed are processes for the preparation the above compounds and methods for use thereof.
    Type: Application
    Filed: October 28, 2010
    Publication date: May 2, 2013
    Applicant: GLAXO GROUP LIMITED
    Inventors: Richard Bellingham, Andrew Mark Buswell, Victoria Mary Ironmonger, Michael Urquhart
  • Novel compound
    Publication number: 20040247667
    Abstract: Invented are pharmaceutical compositions containing paroxetine methanesulfonate.
    Type: Application
    Filed: April 21, 2004
    Publication date: December 9, 2004
    Applicant: SmithKline Beecham p.l.c.
    Inventors: Ahmad Khalaf Al-Deeb Al-Ghazawi, Andrew Simon Craig, David Philip Elder, Victor Witold Jacewicz, David Alan Jones, Deirdre O'Keeffe, Padma Meneaud, Michael Urquhart, Neal Ward
  • Novel compound
    Publication number: 20030203937
    Abstract: Invented are pharmaceutical compositions containing paroxetine methanesulfonate.
    Type: Application
    Filed: May 6, 2003
    Publication date: October 30, 2003
    Applicant: SmithKline Beecham p.l.c.
    Inventors: Ahmad Khalaf Al-Deeb Al-Ghazawi, Andrew Simon Craig, David Philip Elder, Victor Witold Jacewicz, David Alan Jones, Deirdre O'Keeffe, Meneaud Padma Patel, Michael Urquhart, Neal Ward
  • Process for the preparation of substituted thiazolidinedione
    Patent number: 6632947
    Abstract: A process for preparing a compound of formula (I, I) or a tautomeric form thereof or a pharmaceutically acceptable salt thereof or a pharmaceutically acceptable solvate thereof, wherein: J represents O or S; T represents a substituted or unsubstituted aryl group and T1 is O or S; which process comprises reducing a compound of formula (II, II) or a tautomeric form thereof or a salt thereof or a solvate thereof, wherein T and T1 are as defined in relation to formula (I), with a complex hydride reducing agent or a source of a complex hydride reducing agent; and thereafter, as required, preparing a pharmaceutically acceptable salt or a pharmaceutically acceptable solvate of the compound of formula (I) or a tautomeric form thereof.
    Type: Grant
    Filed: November 8, 2001
    Date of Patent: October 14, 2003
    Assignee: SmithKline Beecham plc
    Inventors: Robert Gordon Giles, Norman John Lewis, Stephen Moore, Colin Ripley Pool, John Kirby Quick, Michael Urquhart
  • Pharmaceutical compositions containing thiazolidinedione derivatives and process for their preparation
    Publication number: 20030125358
    Abstract: A method for reducing post-ischaemic injury of the heart and/or improving the functional recovery of the heart following myocardial ischaemia which method comprises administration of an effective, non-toxic amount of a glucose uptake enhancer to a human or non-human mammal in need thereof
    Type: Application
    Filed: February 5, 2003
    Publication date: July 3, 2003
    Applicant: SmithKline Beecham p.l.c.
    Inventors: Robin Edwin Buckingham, Michael Urquhart
  • Novel compound
    Publication number: 20020193406
    Abstract: Piperidine compounds, processes for preparing them, pharmaceutical compositions comprising them and their use in therapy are disclosed.
    Type: Application
    Filed: June 18, 2002
    Publication date: December 19, 2002
    Applicant: SmithKline Beecham plc
    Inventors: Andrew Simon Craig, Victor Witold Jacewicz, Michael Urquhart
  • Process for the preparation of substituted thiazolidinedione
    Publication number: 20020042519
    Abstract: A process for preparing a compound of formula (I, I) or a tautomeric form thereof or a pharmaceutically acceptable salt thereof or a pharmaceutically acceptable solvate thereof, wherein: J represents O or S; T represents a substituted or unsubstituted aryl group and T1 is O or S; which process comprises reducing a compound of formula (II, II) or a tautomeric form thereof or a salt thereof or a solvate thereof, wherein T and T1 are as defined in relation to formula (I), with a complex hydride reducing agent or a source of a complex hydride reducing agent; and thereafter, as required, preparing a pharmaceutically acceptable salt or a pharmaceutically acceptable solvate of the compound of formula (I) or a tautomeric form thereof.
    Type: Application
    Filed: November 8, 2001
    Publication date: April 11, 2002
    Applicant: SmithKline Beecham p.l.c.
    Inventors: Robert Gordon Giles, Norman John Lewis, Stephen Moore, Colin Ripley Pool, John Kirby Quick, Michael Urquhart
  • Novel compound
    Publication number: 20020035130
    Abstract: Piperidine compounds, processes for preparing them, pharmaceutical compositions comprising them and their use in therapy are disclosed.
    Type: Application
    Filed: September 21, 2001
    Publication date: March 21, 2002
    Applicant: SmithKline Beecham p.l.c.
    Inventors: Andrew Simon Craig, Victor Witold Jacewicz, Michael Urquhart
  • Novel compound
    Publication number: 20010023252
    Abstract: Invented are pharmaceutical compositions containing paroxetine methanesulfonate.
    Type: Application
    Filed: March 12, 2001
    Publication date: September 20, 2001
    Applicant: SmithKline Beecham Plc
    Inventors: Ahmad Khalaf Al-Deeb Al-Ghazawi, Andrew Simon Craig, David Philip Elder, Victor Witold Jacewicz, David Alan Jones, Deirdre O'Keeffe, Padma Meneaud Patel, Michael Urquhart, Neal Ward
  • Novel compound
    Publication number: 20010023253
    Abstract: Piperidine compounds, processes for preparing them, pharmaceutical compositions comprising them and their use in therapy are disclosed.
    Type: Application
    Filed: March 14, 2001
    Publication date: September 20, 2001
    Applicant: SmithKline Beecham p.l.c.
    Inventors: Andrew Simon Craig, Victor Witold Jacewicz, Michael Urquhart