Patents by Inventor Michael Valentino

Michael Valentino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11917432
    Abstract: A method for monitoring and rebooting a node of a wireless communications network is disclosed. The method includes acquiring an incident indication for a node site indicative of a performance drop. The method further includes analyzing the incident indication to identify at least one key term. The method further includes accessing a set of prior incidents having a prior incident indication including the key term. The method further includes providing a recommendation to a user device based at least in part on the prior incident indication that includes a site reset for the node site. The method further includes acquiring a resolution indication following the site reset. The method further includes logging the resolution indication as a prior incident indication in the set of prior incidents.
    Type: Grant
    Filed: December 27, 2021
    Date of Patent: February 27, 2024
    Assignee: T-Mobile Innovations LLC
    Inventors: Aditi Saluja, George Cristian Apatachioae, Vikas Ranjan, Michael Valentino
  • Publication number: 20230209374
    Abstract: A method for monitoring and rebooting a node of a wireless communications network is disclosed. The method includes acquiring an incident indication for a node site indicative of a performance drop. The method further includes analyzing the incident indication to identify at least one key term. The method further includes accessing a set of prior incidents having a prior incident indication including the key term. The method further includes providing a recommendation to a user device based at least in part on the prior incident indication that includes a site reset for the node site. The method further includes acquiring a resolution indication following the site reset. The method further includes logging the resolution indication as a prior incident indication in the set of prior incidents.
    Type: Application
    Filed: December 27, 2021
    Publication date: June 29, 2023
    Inventors: Aditi Saluja, George Cristian Apatachioae, Vikas Ranjan, Michael Valentino
  • Patent number: 11396676
    Abstract: The invention provides a series of steps that prepare nucleic acids (RNA and/or DNA) isolated from extracellular vesicles for sequencing. This enables a wide diversity of RNAs and/or DNAs, to be efficiently detected. These can then be used to identify various attributes such as gene expression, alternative splicing, and the detection of both somatic and germline mutations including single nucleotide variants (SNV) and structural variations (insertions/deletions, fusions, inversions).
    Type: Grant
    Filed: October 23, 2017
    Date of Patent: July 26, 2022
    Assignee: Exosome Diagnostics, Inc.
    Inventors: Johan Skog, Sudipto Chakrabortty, Dalin Chan, Michael Valentino, Vasisht Tadigotla, Robert Kitchen, Dominik Grimm, Wei Yu
  • Patent number: 11345957
    Abstract: The present disclosure relates to methods for treating glioblastoma in a subject in need thereof using gene signatures in exosomal RNA derived from the subject. The gene signatures comprise: at least one of FAM229B, ZNF35, CTD-2647L4.4, CABP5, CYP20A1, CEP126, DTX2P1-UPK3BP1-PMS2P11, RP11-507K12.1, KRBA2, CALD1, LRFN1, RP2, SLC2A13, CDKL3, SLC8A3, ANTXR2, TIGD5, AC074289.1 RP11-932O9.7; at least one of tRNA-Lys-CTT-2-2, tRNA-Pro-AGG-2-7, LAMTOR2, RAD51AP1, DENND2A, A1BG, THSD1, CSF1, RP11-332M2.1, ZNF717, ZNF860, ORC6, Clorf50, PSPH, HIST1H4C, CYP2U1, THAP8, TMEM192, NAA20; or at least one of CREBBP, CXCR2 and S100A9. The treatment methods comprise measuring the expression level of at least one of the aforementioned genes in exosomal RNA from a subject and administering to the subject a glioblastoma treatment based on the expression level(s).
    Type: Grant
    Filed: July 18, 2018
    Date of Patent: May 31, 2022
    Assignee: Exosome Diagnostics, Inc.
    Inventors: Robert Kitchen, Michael Valentino, Johan Skog, Vasisht Tadigotla, Dalin Chan, Sudipto Chakrabortty, James Hurley
  • Publication number: 20200224245
    Abstract: The present disclosure relates to methods for providing a clinical assessment of a subject in need thereof using the gene expression level measurements from exosomes derived from the subject.
    Type: Application
    Filed: July 18, 2018
    Publication date: July 16, 2020
    Inventors: Robert KITCHEN, Michael VALENTINO, Johan SKOG, Vasisht TADIGOTLA, Dalin CHAN, Sudipto CHAKRABORTTY, James HURLEY
  • Publication number: 20200208213
    Abstract: The invention provides a series of steps that prepare nucleic acids (RNA and/or DNA) isolated from extracellular vesicles for sequencing. This enables a wide diversity of RNAs and/or DNAs, to be efficiently detected. These can then be used to identify various attributes such as gene expression, alternative splicing, and the detection of both somatic and germline mutations including single nucleotide variants (SNV) and structural variations (insertions/deletions, fusions, inversions).
    Type: Application
    Filed: October 23, 2017
    Publication date: July 2, 2020
    Inventors: Johan SKOG, Sudipto CHAKRABORTTY, Dalin CHAN, Michael VALENTINO, Vasisht TADIGOTLA, Robert KITCHEN, Dominik GRIMM, Wei YU
  • Patent number: 10420826
    Abstract: Compositions comprising antigenic peptides, and their use in inducing an immunoprotective response in a subject against an infection with Streptococcus pneumonia, or for treating or preventing, i.e., reducing risk of, an infection of Streptococcus pneumonia.
    Type: Grant
    Filed: November 10, 2015
    Date of Patent: September 24, 2019
    Assignee: Massachusetts Eye & Ear Infirmary
    Inventors: Michael Valentino, Michael S. Gilmore
  • Publication number: 20180271968
    Abstract: Compositions comprising antigenic peptides, and their use in inducing an immunoprotective response in a subject against an infection with Streptococcus pneumonia, or for treating or preventing, i.e., reducing risk of, an infection of Streptococcus pneumonia.
    Type: Application
    Filed: November 10, 2015
    Publication date: September 27, 2018
    Inventors: Michael Valentino, Michael S. Gilmore
  • Publication number: 20120064039
    Abstract: Compositions comprising a guanylyl cyclase C agonist formulated for sustained specific release of an amount effective to suppress appetite when administered orally to an individual are disclosed. Compositions comprising a guanylyl cyclase C agonist formulated for intravenous delivery in an amount effective to suppress appetite when administered intravenously to an individual are also disclosed. Methods of suppressing appetite in an individual are disclosed.
    Type: Application
    Filed: February 24, 2010
    Publication date: March 15, 2012
    Applicant: THOMAS JEFFERSON UNIVERSITY
    Inventors: Michael Valentino, Jeiru Egeria Lin, Scott A. Waldman
  • Publication number: 20110114624
    Abstract: A universal food holding cabinet has multiple compartments, the temperatures of which are under software control by microprocessors or microcontrollers located on power supply circuit boards for corresponding compartments. Each compartment can have different temperature control requirements with different requirements being met by different programs in different processors, or different operating parameters for the same program. The cabinet is configured to prevent the power supply boards from being installed incorrectly, to provide an address to a power supply circuit board when it is installed and by which a power supply circuit can be addressed by a master controller to receive downloads of executable instructions and/or data.
    Type: Application
    Filed: November 16, 2009
    Publication date: May 19, 2011
    Applicant: PRINCE CASTLE, INC
    Inventors: Terry Tae-IL Chung, Michael Valentino, Jeff Schroeder, Mark Kmiecik, David Reid, Paul Berland, Kerry Berland, Douglas Reinking
  • Publication number: 20110114618
    Abstract: Bezels or escutcheons for a temperature-controlled food holding cabinet are removable and field replaceable by the use of interlocking tabs and detents that hold the escutcheon in place and align the escutcheon to electrical connectors. A tab formed on either the escutcheon or chassis of the cabinet, engages a corresponding detent formed on either the cabinet chassis or the escutcheon. Two tabs and detents are preferably used. One tab engages a corresponding detent with an interference fit.
    Type: Application
    Filed: November 16, 2009
    Publication date: May 19, 2011
    Applicant: PRINCE CASTLE, INC
    Inventors: TERRY TAE-IL CHUNG, MICHAEL VALENTINO, EDWARD EATON, ERIC LARSON, BRIAN W. MATHEWS, KERRY BERLAND, DOUGLAS REINKING
  • Publication number: 20110114625
    Abstract: A universal food holding cabinet has multiple compartments, the temperatures of which are under software control by microprocessors or microcontrollers located on power supply circuit boards for corresponding compartments. Each compartment can have different temperature control requirements with different requirements being met by a different program in different processors, or different operating parameters for the same program. The cabinet is configured to prevent the power supply boards from being installed incorrectly, to provide an address to a power supply circuit board when it is installed and by which a power supply circuit can be addressed by a master controller.
    Type: Application
    Filed: November 16, 2009
    Publication date: May 19, 2011
    Applicant: PRINCE CASTLE, INC
    Inventors: TERRY TAE-IL CHUNG, MICHAEL VALENTINO, JEFF SCHROEDER, MARK KMIECIK, DAVID REID, PAUL BERLAND, KERRY BERLAND, DOUGLAS REINKING
  • Publication number: 20060220797
    Abstract: A device for blocking the ringing of a doorbell is disclosed. The device has a cover body with front, side, top and bottom sides. The front side also has a selectively closable opening, which has an outer perimeter. The front side also has at least one hole in it, which allows passage of a securing device, through the hole for securing the device. The selectively closeable opening has a plurality of panels slidably attached to the interior surface of the front side. The panels are slidably movable between an open position and a closed position. In the open position, the panels can stack, one in front of the other in a position that is substantially outside the outer perimeter of the selectively closable opening in the front side. The panels can have written indicia on them which is viewable when the panels are in the closed position.
    Type: Application
    Filed: March 7, 2006
    Publication date: October 5, 2006
    Inventors: Michael Valentino, Kerri Valentino
  • Patent number: D813342
    Type: Grant
    Filed: January 16, 2017
    Date of Patent: March 20, 2018
    Inventor: Michael Valentino Vagnino, Jr.