Patents by Inventor Michael Valentino
Michael Valentino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11917432Abstract: A method for monitoring and rebooting a node of a wireless communications network is disclosed. The method includes acquiring an incident indication for a node site indicative of a performance drop. The method further includes analyzing the incident indication to identify at least one key term. The method further includes accessing a set of prior incidents having a prior incident indication including the key term. The method further includes providing a recommendation to a user device based at least in part on the prior incident indication that includes a site reset for the node site. The method further includes acquiring a resolution indication following the site reset. The method further includes logging the resolution indication as a prior incident indication in the set of prior incidents.Type: GrantFiled: December 27, 2021Date of Patent: February 27, 2024Assignee: T-Mobile Innovations LLCInventors: Aditi Saluja, George Cristian Apatachioae, Vikas Ranjan, Michael Valentino
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Publication number: 20230209374Abstract: A method for monitoring and rebooting a node of a wireless communications network is disclosed. The method includes acquiring an incident indication for a node site indicative of a performance drop. The method further includes analyzing the incident indication to identify at least one key term. The method further includes accessing a set of prior incidents having a prior incident indication including the key term. The method further includes providing a recommendation to a user device based at least in part on the prior incident indication that includes a site reset for the node site. The method further includes acquiring a resolution indication following the site reset. The method further includes logging the resolution indication as a prior incident indication in the set of prior incidents.Type: ApplicationFiled: December 27, 2021Publication date: June 29, 2023Inventors: Aditi Saluja, George Cristian Apatachioae, Vikas Ranjan, Michael Valentino
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Patent number: 11396676Abstract: The invention provides a series of steps that prepare nucleic acids (RNA and/or DNA) isolated from extracellular vesicles for sequencing. This enables a wide diversity of RNAs and/or DNAs, to be efficiently detected. These can then be used to identify various attributes such as gene expression, alternative splicing, and the detection of both somatic and germline mutations including single nucleotide variants (SNV) and structural variations (insertions/deletions, fusions, inversions).Type: GrantFiled: October 23, 2017Date of Patent: July 26, 2022Assignee: Exosome Diagnostics, Inc.Inventors: Johan Skog, Sudipto Chakrabortty, Dalin Chan, Michael Valentino, Vasisht Tadigotla, Robert Kitchen, Dominik Grimm, Wei Yu
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Patent number: 11345957Abstract: The present disclosure relates to methods for treating glioblastoma in a subject in need thereof using gene signatures in exosomal RNA derived from the subject. The gene signatures comprise: at least one of FAM229B, ZNF35, CTD-2647L4.4, CABP5, CYP20A1, CEP126, DTX2P1-UPK3BP1-PMS2P11, RP11-507K12.1, KRBA2, CALD1, LRFN1, RP2, SLC2A13, CDKL3, SLC8A3, ANTXR2, TIGD5, AC074289.1 RP11-932O9.7; at least one of tRNA-Lys-CTT-2-2, tRNA-Pro-AGG-2-7, LAMTOR2, RAD51AP1, DENND2A, A1BG, THSD1, CSF1, RP11-332M2.1, ZNF717, ZNF860, ORC6, Clorf50, PSPH, HIST1H4C, CYP2U1, THAP8, TMEM192, NAA20; or at least one of CREBBP, CXCR2 and S100A9. The treatment methods comprise measuring the expression level of at least one of the aforementioned genes in exosomal RNA from a subject and administering to the subject a glioblastoma treatment based on the expression level(s).Type: GrantFiled: July 18, 2018Date of Patent: May 31, 2022Assignee: Exosome Diagnostics, Inc.Inventors: Robert Kitchen, Michael Valentino, Johan Skog, Vasisht Tadigotla, Dalin Chan, Sudipto Chakrabortty, James Hurley
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Publication number: 20200224245Abstract: The present disclosure relates to methods for providing a clinical assessment of a subject in need thereof using the gene expression level measurements from exosomes derived from the subject.Type: ApplicationFiled: July 18, 2018Publication date: July 16, 2020Inventors: Robert KITCHEN, Michael VALENTINO, Johan SKOG, Vasisht TADIGOTLA, Dalin CHAN, Sudipto CHAKRABORTTY, James HURLEY
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Publication number: 20200208213Abstract: The invention provides a series of steps that prepare nucleic acids (RNA and/or DNA) isolated from extracellular vesicles for sequencing. This enables a wide diversity of RNAs and/or DNAs, to be efficiently detected. These can then be used to identify various attributes such as gene expression, alternative splicing, and the detection of both somatic and germline mutations including single nucleotide variants (SNV) and structural variations (insertions/deletions, fusions, inversions).Type: ApplicationFiled: October 23, 2017Publication date: July 2, 2020Inventors: Johan SKOG, Sudipto CHAKRABORTTY, Dalin CHAN, Michael VALENTINO, Vasisht TADIGOTLA, Robert KITCHEN, Dominik GRIMM, Wei YU
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Patent number: 10420826Abstract: Compositions comprising antigenic peptides, and their use in inducing an immunoprotective response in a subject against an infection with Streptococcus pneumonia, or for treating or preventing, i.e., reducing risk of, an infection of Streptococcus pneumonia.Type: GrantFiled: November 10, 2015Date of Patent: September 24, 2019Assignee: Massachusetts Eye & Ear InfirmaryInventors: Michael Valentino, Michael S. Gilmore
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Publication number: 20180271968Abstract: Compositions comprising antigenic peptides, and their use in inducing an immunoprotective response in a subject against an infection with Streptococcus pneumonia, or for treating or preventing, i.e., reducing risk of, an infection of Streptococcus pneumonia.Type: ApplicationFiled: November 10, 2015Publication date: September 27, 2018Inventors: Michael Valentino, Michael S. Gilmore
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Publication number: 20120064039Abstract: Compositions comprising a guanylyl cyclase C agonist formulated for sustained specific release of an amount effective to suppress appetite when administered orally to an individual are disclosed. Compositions comprising a guanylyl cyclase C agonist formulated for intravenous delivery in an amount effective to suppress appetite when administered intravenously to an individual are also disclosed. Methods of suppressing appetite in an individual are disclosed.Type: ApplicationFiled: February 24, 2010Publication date: March 15, 2012Applicant: THOMAS JEFFERSON UNIVERSITYInventors: Michael Valentino, Jeiru Egeria Lin, Scott A. Waldman
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Publication number: 20110114624Abstract: A universal food holding cabinet has multiple compartments, the temperatures of which are under software control by microprocessors or microcontrollers located on power supply circuit boards for corresponding compartments. Each compartment can have different temperature control requirements with different requirements being met by different programs in different processors, or different operating parameters for the same program. The cabinet is configured to prevent the power supply boards from being installed incorrectly, to provide an address to a power supply circuit board when it is installed and by which a power supply circuit can be addressed by a master controller to receive downloads of executable instructions and/or data.Type: ApplicationFiled: November 16, 2009Publication date: May 19, 2011Applicant: PRINCE CASTLE, INCInventors: Terry Tae-IL Chung, Michael Valentino, Jeff Schroeder, Mark Kmiecik, David Reid, Paul Berland, Kerry Berland, Douglas Reinking
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Publication number: 20110114618Abstract: Bezels or escutcheons for a temperature-controlled food holding cabinet are removable and field replaceable by the use of interlocking tabs and detents that hold the escutcheon in place and align the escutcheon to electrical connectors. A tab formed on either the escutcheon or chassis of the cabinet, engages a corresponding detent formed on either the cabinet chassis or the escutcheon. Two tabs and detents are preferably used. One tab engages a corresponding detent with an interference fit.Type: ApplicationFiled: November 16, 2009Publication date: May 19, 2011Applicant: PRINCE CASTLE, INCInventors: TERRY TAE-IL CHUNG, MICHAEL VALENTINO, EDWARD EATON, ERIC LARSON, BRIAN W. MATHEWS, KERRY BERLAND, DOUGLAS REINKING
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Publication number: 20110114625Abstract: A universal food holding cabinet has multiple compartments, the temperatures of which are under software control by microprocessors or microcontrollers located on power supply circuit boards for corresponding compartments. Each compartment can have different temperature control requirements with different requirements being met by a different program in different processors, or different operating parameters for the same program. The cabinet is configured to prevent the power supply boards from being installed incorrectly, to provide an address to a power supply circuit board when it is installed and by which a power supply circuit can be addressed by a master controller.Type: ApplicationFiled: November 16, 2009Publication date: May 19, 2011Applicant: PRINCE CASTLE, INCInventors: TERRY TAE-IL CHUNG, MICHAEL VALENTINO, JEFF SCHROEDER, MARK KMIECIK, DAVID REID, PAUL BERLAND, KERRY BERLAND, DOUGLAS REINKING
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Publication number: 20060220797Abstract: A device for blocking the ringing of a doorbell is disclosed. The device has a cover body with front, side, top and bottom sides. The front side also has a selectively closable opening, which has an outer perimeter. The front side also has at least one hole in it, which allows passage of a securing device, through the hole for securing the device. The selectively closeable opening has a plurality of panels slidably attached to the interior surface of the front side. The panels are slidably movable between an open position and a closed position. In the open position, the panels can stack, one in front of the other in a position that is substantially outside the outer perimeter of the selectively closable opening in the front side. The panels can have written indicia on them which is viewable when the panels are in the closed position.Type: ApplicationFiled: March 7, 2006Publication date: October 5, 2006Inventors: Michael Valentino, Kerri Valentino
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Patent number: D813342Type: GrantFiled: January 16, 2017Date of Patent: March 20, 2018Inventor: Michael Valentino Vagnino, Jr.