Patents by Inventor Michael W. Dahm

Michael W. Dahm has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090186341
    Abstract: The invention describes a container (1) for separating tumour cells, in particular disseminated tumour cells (9), from a biological sample, with a closed end and an end which can be opened (2, 3). It contains a thixotropic substance (4) with a specific density selected from a range with a lower limit of 1.055 g/cm3, preferably 1.057 g/cm3, in particular 1.060 g/cm3, and an upper limit of 1.070 g/cm3, preferably 1.069 g/cm3, in particular 1.065 g/cm3, and optionally a separation medium (5) in the form of a density gradient with a specific density selected from a range with a lower limit of 1.060 g/cm3, preferably 1.065 g/cm3, in particular 1.070 g/cm3, and an upper limit of 1.085 g/cm3, preferably 1.080 g/cm3, in particular 1.075 g/cm3.
    Type: Application
    Filed: February 20, 2006
    Publication date: July 23, 2009
    Applicant: HEXAL AKTIENGESELLSCHAFT
    Inventor: Michael W. Dahm
  • Patent number: 7323304
    Abstract: The invention relates to a method for enriching tumor cells from a body fluid, in which a cell separation medium of a specific density is overlaid with the body fluid and it is subsequently determined whether the enriched cells express an epithelial marker, for example a cytokeratin. A kit suitable for this method is likewise provided.
    Type: Grant
    Filed: August 7, 2003
    Date of Patent: January 29, 2008
    Assignee: Hexal Gentech ForschungsGmbH
    Inventor: Michael W. Dahm
  • Patent number: 7211433
    Abstract: The invention relates to a method for the enrichment or depletion of tumor cells from a body fluid, in which a cell separation medium of specific density is overlaid with the body fluid and is centrifuged. A kit suitable for this method is likewise provided.
    Type: Grant
    Filed: February 2, 2000
    Date of Patent: May 1, 2007
    Assignee: Hexal Gentech Forschungs GmbH
    Inventors: Michael W. Dahm, Robert C. Phelps, Carsten Brockmeyer
  • Patent number: 6821726
    Abstract: The invention relates to a method for quantitatively analyzing tumor cells in a body fluid. According to the inventive method, the test sample to be examined is first subjected to a method for accumulating or depleting tumor cells, and a reaction is carried out on the accumulated or depleted tumor cells. During the reaction, the mRNA which codes for the catalytic subunit of the telomerase is specifically amplified, and afterwards, the quantity of amplified nucleic acid is quantitatively analyzed. The invention also relates to test kits suited for the invented method.
    Type: Grant
    Filed: August 4, 2000
    Date of Patent: November 23, 2004
    Inventors: Michael W. Dahm, Robert C. Phelps, Carsten Brockmeyer
  • Patent number: 6582904
    Abstract: A method for the quantification of tumor cells in a body fluid is disclosed and entails first carrying out a reaction with the sample to be investigated, in which the RNA component of telomerase is specifically amplified, and then the amount of amplified nucleic acid is determined quantitatively, as are test kits suitable therefor.
    Type: Grant
    Filed: May 14, 1998
    Date of Patent: June 24, 2003
    Inventor: Michael W. Dahm
  • Publication number: 20020012969
    Abstract: A method for the quantification of tumor cells in a body fluid is disclosed and entails first carrying out a reaction with the sample to be investigated, in which the RNA component of telomerase is specifically amplified, and then the amount of amplified nucleic acid is determined quantitatively, as are test kits suitable therefor.
    Type: Application
    Filed: May 14, 1998
    Publication date: January 31, 2002
    Inventor: MICHAEL W. DAHM