Abstract: An innovative analytical method comprising the step of exposing a first substrate to at least one tobacco component, a tobacco composition, or at least one component derived from tobacco, such as, but not limited to, at least one tobacco smoke component. An additional step may comprise the step of preparing a second substrate not exposed to the tobacco component in an identical manner, wherein the second substrate may receive a different exposure, no exposure, or exposure in combination with another factor or condition, or any combination thereof. Additional steps may comprise collecting at least one first sample from the first substrate and at least one second sample from the second substrate, and analyzing the first and second sample by using at least one analytical characterization technique, wherein the analytical characterization technique comprises NMR spectroscopy.

Abstract: An air sampling system and a calibration system therefor are disclosed for use therewith in order to provide air sampling for, for example, environmental tobacco smoke aerosol in a portable personal air sampling system. The air sampling system utilizes a sampler head having a manifold block which allows for the collection of air for studying both the particulate and vapor phases of environmental tobacco smoke aerosol using only a single pump. An air flow calibrating system is utilized to measure and calibrate the air flowing through the two collection devices used in connection with the manifold block in which the air flow through the two sampling assemblies is simultaneously read out.