Abstract: Device and methods for extracting and analyzing nucleic acids from biological samples.

Abstract: Fluorescent pH detector and methods for measuring pH using the fluorescent pH detector.

Abstract: Fluorescent pH detector and methods for measuring pH using the fluorescent pH detector.

Abstract: Processes for extracting nucleic acid from a biological sample and related assemblies and kits are disclosed. The processes comprise the steps of (a) providing a device comprising an inner surface, an outer surface, a first port, and a second port, wherein the inner surface is composed of unmodified, smooth glass and defines a tubular lumen providing fluid communication between the first port and second port, wherein the lumen is circular, oval, or elliptical in cross-section, and wherein the lumen is essentially free of nucleic acid-specific binding sites; (b) introducing a nucleic acid-containing sample into the lumen of the device via the first port; (c) allowing nucleic acid in the sample to bind to the unmodified smooth glass surface; and (d) washing the bound nucleic acid.

Abstract: Fluorescent pH detector and methods for measuring pH using the fluorescent pH detector.

Abstract: Oligonucleotide probes containing two labels are provided and are useful in hybridization assays. The probes can also contain a minor groove binding group.

Abstract: Oligonucleotide probes containing two labels are provided and are useful in hybridization assays. The probes can also contain a minor groove binding group.

Abstract: Device and methods for extracting and analyzing nucleic acids from biological samples.

Abstract: Oligonucleotide probes containing two labels are provided and are useful in hybridization assays. The probes can also contain a minor groove binding group.

Abstract: Fluorescent pH detector and methods for measuring pH using the fluorescent pH detector.

Abstract: Methods and apparatus for testing the sterility of a product to be administered to a patient. The sterility of the product is tested by monitoring the pH change of a culture medium in contact with any culturable organisms (e.g., bacteria) that are collected by filtration of the product to be tested.

Abstract: Fluorescent pH detector and methods for measuring pH using the fluorescent pH detector.

Abstract: Device and methods for extracting and analyzing nucleic acids from biological samples.

Abstract: Dye reagents useful in labeling biological materials are provided along with methods for their use.

Abstract: Devices, processes, and kits for the extraction of nucleic acids from biological samples are disclosed. The devices comprise a first port, a second port, and a binding chamber intermediate and in fluid communication with the first port and the second port. The binding chamber comprises an unmodified flat glass surface effective for binding a heterogeneous population of nucleic acids. The first port, second port, and binding chamber define a continuous fluid pathway that is essentially free of nucleic acid-specific binding sites.

Abstract: A microfluidic device for isolating genomic DNA from human leukocytes, simultaneously capturing and measuring the DNA for simplifying genetic analysis. The device contains a fluid inlet port, a fluid outlet port, and a DNA binding channel in contact with the fluid inlet port wherein at least a portion of at least one surface within the DNA binding channel is modified with a binding reagent such that DNA is preferentially bound to the surface.

Abstract: Dye reagents useful in labeling biological materials are provided along with methods for their use.

Abstract: Dye reagents useful in labeling biological materials are provided along with methods for their use.

Abstract: The present invention provides a nucleoside comprising a pyrazolopyrimidine base and a process for producing the same. In particular, the processes of the present invention comprises using a halogenated pyrazolopyrimidine base and removing the halogen after the base is coupled to a sugar moiety. The presence of the halogen on the nucleoside base allows facile and economical production of a large quantity of nucleosides.

Abstract: A wheeled mover for a picnic table and a method of use is disclosed. The mover includes two posts attached to opposite sides of a table. The lower ends of the posts terminate in wheels. The posts pivot between a first position wherein the picnic table rests upon the ground and a second position wherein the picnic table is raised for wheeled transport.