Patents by Inventor Michel Crepin

Michel Crepin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bisphosphonate derivatives, their preparations and uses
    Patent number: 7005533
    Abstract: The present invention relates to derivatives of 1-hydroxymethylene-1,1-bisphosphonic acid, the pharmaceutical compositions comprising them, and their application in therapeutics, particularly for the treatment of cancerous tumors. It is also directed to a methods of preparation of such derivatives.
    Type: Grant
    Filed: July 12, 2004
    Date of Patent: February 28, 2006
    Assignee: Universite Paris 13
    Inventors: Marc Lecouvey, Yves Leroux, Michel Kraemer, Michel Crepin, Driss El Manouni, Malika Louriki
  • Bisphosphonate derivatives, their preparations and uses
    Publication number: 20040266735
    Abstract: The present invention relates to derivatives of 1-hydroxymethylene-1,1-bisphosphonic acid, the pharmaceutical compositions comprising them, and their application in therapeutics, particularly for the treatment of cancerous tumors. It is also directed to a methods of preparation of such derivatives.
    Type: Application
    Filed: July 12, 2004
    Publication date: December 30, 2004
    Applicant: Universite Paris 13
    Inventors: Marc Lecouvey, Yves Leroux, Michel Kraemer, Michel Crepin, Driss El Manouni, Malika Louriki
  • Pharmaceutical composition containing at least a polymer combined with or conjugated to at least a phenylalkylcarboxylic acid salt, conjugate polymers and uses thereof
    Publication number: 20030171333
    Abstract: The invention concerns a pharmaceutical composition containing at least a polymer associated or conjugated with at least a phenylalkylcarboxylic acid derivative, novel polymers conjugated with at least a phenylalkylcarboxylic acid derivative and their uses in particular in cancer treatment.
    Type: Application
    Filed: May 2, 2003
    Publication date: September 11, 2003
    Inventors: Thierry Avramoglou, Rosita Bagheri, Frederic Chaubet, Michel Crepin, Latifa Dahri, Melanie Dibenedetto, Claudia Gervelas, Remi Huynh, Jacqueline Jozefonvicz
  • Bisphosphonate derivatives, their preparations and uses
    Publication number: 20030036537
    Abstract: The present invention relates to derivatives of 1-hydroxymethylene-1,1-bisphosphonic acid, the pharmaceutical compositions comprising them, and their application in therapeutics, particularly for the treatment of cancerous tumors. It is also directed to a methods of preparation of such derivatives.
    Type: Application
    Filed: July 15, 2002
    Publication date: February 20, 2003
    Inventors: Marc Lecouvey, Yves Leroux, Michel Kraemer, Michel Crepin, Driss El Manouni, Malika Louriki
  • Process and reagents for the detection of a monocaternary nucleic acid, particularly a RNA in a biological material and particularly in leucocyte preparations
    Patent number: 5070009
    Abstract: The invention relates to a process for the in vitro detection of a determined RNA, particularly of a mRNA connected with a genetic abnormality in a biological material. This process comprises a treatment of the cells contained in that material for the sake of releasing their cellular components and of exposing the RNAs yet without denaturing other nucleic acids, and then the detection operation comprising contacting RNA sought to be detected, in presence of the other cellular components, with a nucleotidic sequence complementary of the RNA sought.
    Type: Grant
    Filed: September 15, 1988
    Date of Patent: December 3, 1991
    Assignee: Institut Pasteur
    Inventor: Michel Crepin