Patents by Inventor Michel L. P. M. Verhoeven

Michel L. P. M. Verhoeven has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nitric oxide-releasing metallic medical devices
    Patent number: 6270779
    Abstract: Biocompatible metallic medical devices having silanized surfaces coupled to nucleophile residues that release sustained, therapeutic amounts of nitric oxide to specific sites within a mammalian body are provided. Additionally, the biocompatible metallic medical devices can also be provided with anti-thrombogenic, lubricious coatings that release sustained, therapeutic amounts of nitric oxide. Moreover, the silanized metallic devices are surprisingly durable when exposed to harsh chemical methods often needed to bind nitric oxide-releasing functional groups to nucleophile residues. Furthermore, methods are provided for producing stable, silanized, sustained nitric oxide-releasing metallic medical devices.
    Type: Grant
    Filed: May 10, 2000
    Date of Patent: August 7, 2001
    Assignee: United States of America
    Inventors: Anthony L. Fitzhugh, Peiwen Cheng, Joseph Saavedra, Robert Cafferata, Marc Hendriks, Larry K. Keefer, Eugene Tedeschi, Michel L. P. M. Verhoeven
  • Intramuscular stimulation lead with enhanced infection resistance
    Patent number: 5834051
    Abstract: To minimize the incidence and consequences of device related infection that occur after prosthetics implants of neuro-muscular stimulating devices, an infection resistant intra-muscular lead has been developed and is disclosed herein. Infection incidence has been decreased by using biomaterials able to release antibacterial drugs (gentamicin) at a controlled rate for the first 3-6 weeks after implant.
    Type: Grant
    Filed: February 19, 1997
    Date of Patent: November 10, 1998
    Assignee: Medtronic, Inc.
    Inventors: Jean A. Woloszko, Marc Hendriks, Patrick T. Cahalan, Michel L. P. M. Verhoeven, Linda L. Cahalan, Antoine N. J. Camps
  • Intramuscular stimulation lead with enhanced infection resistance
    Patent number: 5755758
    Abstract: To minimize the incidence and consequences of device related infection that occur after prosthetics implants of neuro-muscular stimulating devices, an infection resistant intramuscular lead has been developed. Infection incidence has been decreased by using biomaterials able to release antibacterial drugs (gentamicin) at a controlled rate for the first 3-6 weeks after implant.
    Type: Grant
    Filed: November 7, 1995
    Date of Patent: May 26, 1998
    Assignee: Medtronic, Inc.
    Inventors: Jean A. Woloszko, Marc Hendriks, Patrick T. Cahalan, Michel L. P. M. Verhoeven, Linda L. Cahalan, Antoine N. J. Camps