Patents by Inventor Michele A. Weidner-Wells

Michele A. Weidner-Wells has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ?-ketoamide derivatives useful endothelial lipase inhibitors
    Patent number: 8476302
    Abstract: The present invention is directed to ?-ketoamide derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by endothelial lipase, for example, cardiovascular disorders.
    Type: Grant
    Filed: September 26, 2011
    Date of Patent: July 2, 2013
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Michael N. Greco, Margery A. Connelly, Shyamali Ghosh, Dennis J. Hlasta, Edward C. Lawson, Eric Strobel, Michele A. Weidner-Wells, Hong Ye
  • ALPHA-KETOAMIDE DERIVATIVES USEFUL ENDOTHELIAL LIPASE INHIBITORS
    Publication number: 20120077847
    Abstract: The present invention is directed to ?-ketoamide derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by endothelial lipase, for example, cardiovascular disorders.
    Type: Application
    Filed: September 26, 2011
    Publication date: March 29, 2012
    Inventors: Michael N. Greco, Margery A. Connelly, Shyamali Ghosh, Dennis J. Hlasta, Edward C. Lawson, Eric Strobel, Michele A. Weidner-Wells, Hong Ye
  • C-7 isoxazolinyl quinolone / naphthyridine derivatives useful as antibacterial agents
    Patent number: 7902227
    Abstract: The present invention relates to C-7 isoxazolyl quinoline/naphthyridine derivatives useful as antimicrobial compounds, pharmaceutical compositions comprising said derivatives and the use of said derivatives and pharmaceutical compositions as antimicrobial agents against pathogenic microorganisms, particularly against resistant microbes.
    Type: Grant
    Filed: July 28, 2008
    Date of Patent: March 8, 2011
    Assignee: Janssen Pharmaceutica NV.
    Inventors: Mark J. Macielag, Michele A. Weidner-Wells, Shu-Chen Lin
  • C-7 Isoxazolinyl Quinolone / Naphthyridine Derivatives Useful as Antibacterial Agents
    Publication number: 20090029980
    Abstract: The present invention relates to C-7 isoxazolyl quinoline/naphthyridine derivatives useful as antimicrobial compounds, pharmaceutical compositions comprising said derivatives and the use of said derivatives and pharmaceutical compositions as antimicrobial agents against pathogenic microorganisms, particularly against resistant microbes.
    Type: Application
    Filed: July 28, 2008
    Publication date: January 29, 2009
    Inventors: Mark J. Macielag, Michele A. Weidner-Wells, Shu-Chen Lin
  • 7-Amino alkylidenyl-heterocyclic quinolones and naphthyridones
    Publication number: 20060052359
    Abstract: The present invention relates to compounds having a structure according to Formula I wherein n, m, z, R, R2, R3, R4, R5, R6, A, E, X, Y, a and b are as defined above; or an optical isomer, diastereomer or enantiomer thereof; a pharmaceutically acceptable salt, hydrate, or prodrug thereof.
    Type: Application
    Filed: March 21, 2005
    Publication date: March 9, 2006
    Inventors: Eugene Grant, Mark Macielag, Steven Paget, Michele Weidner-Wells, Xiaoqing Xu, Xiaodong Xu
  • Pyridoarylphenly oxazolidinone antibacterials, and related compositions and methods
    Patent number: 6951863
    Abstract: Pyridoarylphenyl oxazolidinone compounds of the formula: in which the substituents have the meaning indicated in the description. These compounds are useful as antibacterial agents.
    Type: Grant
    Filed: February 6, 2002
    Date of Patent: October 4, 2005
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Steven D. Paget, Michele A. Weidner-Wells, Harvey M. Werblood
  • 7-Amino alkylidenyl-heterocyclic quinolones and naphthyridones
    Publication number: 20050101588
    Abstract: The present invention relates to compounds having a structure according to Formula I wherein n, m, z, R, R2, R3, R4, R5, R6, A, E, X, Y, a and b are as defined above; or an optical isomer, diastereomer or enantiomer thereof; a pharmaceutically acceptable salt, hydrate, or prodrug thereof.
    Type: Application
    Filed: September 9, 2004
    Publication date: May 12, 2005
    Inventors: Eugene Grant, Mark Macielag, Xiaoqing Xu, Steven Paget, Michele Weidner-Wells
  • Isoxazoles and oxadiazoles as anti-inflammatory inhibitors of IL-8
    Publication number: 20030216386
    Abstract: The invention relates to isoxazole and oxadiazole compounds of Formulae I and II, 1
    Type: Application
    Filed: April 10, 2003
    Publication date: November 20, 2003
    Inventors: Michele A. Weidner-Wells, Todd C. Henninger, Dennis J. Hlasta
  • Pyridoarylphenyl oxazolidinone antibacterials, and related compositions and methods
    Publication number: 20030176422
    Abstract: Pyridoarylphenyl oxazolidinone compounds of the formula: 1
    Type: Application
    Filed: February 6, 2002
    Publication date: September 18, 2003
    Inventors: Steven D. Paget, Michele A. Weidner-Wells, Harvey M. Werblood
  • Isoxazoles and oxadiazoles as anti-inflammatory inhibitors of IL-8
    Patent number: 6579880
    Abstract: The invention relates to isoxazole and oxadiazole compounds of Formulae I and II, pharmaceutical compositions containing the compounds, and methods for their production and use. These compounds are effective in inhibiting the action of IL-8 and are thus useful as anti-inflammatory agents for a variety of diseases.
    Type: Grant
    Filed: June 6, 2001
    Date of Patent: June 17, 2003
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Michele A. Weidner-Wells, Todd C. Henninger, Dennis J. Hlasta
  • Piperidinyloxy and pyrrolidinyloxy oxazolidinone antibacterials
    Patent number: 6518285
    Abstract: Piperidinyloxy, pyrrolidinyloxyl and azetidinyloxy compounds of the formula: wherein R1 is a piperidinyl, pyrrolidinyl or azetidinyl moiety as described herein and in which the substituents have the meaning indicated in the description. These compounds are useful as antibacterial agents.
    Type: Grant
    Filed: December 5, 2000
    Date of Patent: February 11, 2003
    Assignee: Ortho McNeil Pharmaceutical, Inc.
    Inventors: Michele A. Weidner-Wells, Christine Boggs, Dennis Hlasta, Erin Nelson
  • Piperidinyloxy and pyrrolidinyloxy oxazolidinone antibacterials
    Publication number: 20020103377
    Abstract: Piperidinyloxy, pyrrolidinyloxyl and azetidinyloxy compounds of the formula: 1
    Type: Application
    Filed: December 5, 2000
    Publication date: August 1, 2002
    Inventors: Michele A. Weidner-Wells, Christine Boggs, Dennis Hlasta, Erin Nelson
  • Isoxazoles and oxadiazoles as anti-inflammatory inhibitors of IL-8
    Publication number: 20020049213
    Abstract: The invention relates to isoxazole and oxadiazole compounds of Formulae I and II, 1
    Type: Application
    Filed: June 6, 2001
    Publication date: April 25, 2002
    Inventors: Michele A. Weidner-Wells, Todd C. Henninger, Dennis J. Hlasta