Patents by Inventor Michele di Schiena

Michele di Schiena has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9901613
    Abstract: Disclosed is a complex of pea protein and proanthocyanidins for use in the treatment of disorders caused by alterations of the intestinal epithelial tissue.
    Type: Grant
    Filed: December 15, 2016
    Date of Patent: February 27, 2018
    Assignee: NOVINTETHICAL PHARMA SA
    Inventors: Miguel Angel Alonso, Marco Di Fulvio, Michele Di Schiena
  • Publication number: 20170095528
    Abstract: Disclosed is a complex of pea protein and proanthocyanidins for use in the treatment of disorders caused by alterations of the intestinal epithelial tissue.
    Type: Application
    Filed: December 15, 2016
    Publication date: April 6, 2017
    Inventors: Miguel Angel Alonso, Marco Di Fulvio, Michele Di Schiena
  • Publication number: 20160051626
    Abstract: Disclosed is a complex of pea protein and proanthocyanidins for use in the treatment of disorders caused by alterations of the intestinal epithelial tissue.
    Type: Application
    Filed: March 27, 2014
    Publication date: February 25, 2016
    Inventors: Miguel Angel Alonso, Marco Di Fulvio, Michele Di Schiena
  • Publication number: 20150290173
    Abstract: The invention generally relates to compositions comprising a soluble chitosan derivative and an H2 receptor antagonist, and the use of the compositions for treating skin or mucosal diseases, such as inflammatory diseases or infectious disease.
    Type: Application
    Filed: November 26, 2013
    Publication date: October 15, 2015
    Applicant: ZARZATECH, INC.
    Inventors: Sonia Divney, Michele Di Schiena
  • Patent number: 9011902
    Abstract: Compositions for vaginal use comprising lupulus (Humulus lupulus) and an excipient base suitable for application in the vaginal and/or vulvar region, for the treatment of vaginal dryness (atrophic vaginitis) and of the disorders correlated thereto, pruritus, burning sensation, dryness, dyspareunia; they are also particularly useful for delaying and attenuating the changes in the physiological trophism of the vulvar and vaginal tissue and mucosa.
    Type: Grant
    Filed: July 22, 2008
    Date of Patent: April 21, 2015
    Assignee: Polichem SA
    Inventor: Michele Di Schiena
  • Publication number: 20090035361
    Abstract: Compositions for vaginal use comprising lupulus (Humulus lupulus) and an excipient base suitable for application in the vaginal and/or vulvar region, for the treatment of vaginal dryness (atrophic vaginitis) and of the disorders correlated thereto, pruritus, burning sensation, dryness, dyspareunia; they are also particularly useful for delaying and attenuating the changes in the physiological trophism of the vulvar and vaginal tissue and mucosa.
    Type: Application
    Filed: July 22, 2008
    Publication date: February 5, 2009
    Applicant: POLICHEM S.A.
    Inventor: Michele Di Schiena
  • Patent number: 4948805
    Abstract: The salt of diclofenac with a cyclic organic base is prepared by dissolving diclofenac in a suitable organic solvent, adding said cyclic organic base, reacting the two components together, removing the solvent and crystallizing the product obtained.Said salt is water soluble to an extent from 20% w/v to an extent exceeding 50% w/v, and is used to prepared pharmaceutical compositions preferably in granular form for use by dissolving in water for oral administration.
    Type: Grant
    Filed: November 9, 1987
    Date of Patent: August 14, 1990
    Assignee: Altergon S. A. & Ricerfarma Srl.
    Inventors: Antonio Ziggiotti, Michele Di Schiena
  • Patent number: 4405618
    Abstract: New derivatives of 1,3-thiazolidin-4-yl carboxylic acid of the general formula I ##STR1## wherein R represents hydrogen, (C.sub.1 -.sub.4)alkyl, aralkyl, phenyl, phenyl substituted by a halogen atom or a methoxy group, formyl, acyl, trimethylsilyl;R' represents hydrogen, a pharmaceutically acceptable inorganic or organic cation, (C.sub.1 -.sub.4)alkyl, 2,2,2-trichloroethyl, acetonyl, benzyl, benzyl substituted by nitro or methoxy, phenyl, nitrophenyl, benzhydryl or trimethylsilyl;R' may also represent a radical capable of providing metabolic activation in vivo selected from acetoxymethyl, pivaloyloxymethyl, phthalidyl, benzoyloxymethyl, 5-indanyl, a group of formula ##STR2## or a group of formula ##STR3## in which R" stands for (C.sub.1 -.sub.4)alkyl, (C.sub.5 -.sub.6)cycloalkyl or aryl; A represents hydrogen, halogen, N.sub.3, OH, NH.sub.2 ; or a quaternary N-atom, particularly ##STR4## (and in this case R' is a negative charge; or a O--CO--NH.sub.
    Type: Grant
    Filed: July 1, 1981
    Date of Patent: September 20, 1983
    Assignee: Ausonia Farmaceutici s.r.l.
    Inventors: Michele Di Schiena, Vittoria Orru
  • Patent number: 4389407
    Abstract: New derivatives of 1,3-thiazolidin-4-yl carboxylic acid of the general formula I ##STR1## wherein: R represents hydrogen, (C.sub.1 -.sub.4)alkyl, aralkyl, phenyl, phenyl substituted by a halogen atom or a methoxy group, formyl, acyl, trimethylsilyl;R' represents hydrogen, a pharmaceutically acceptable inorganic or organic cation, (C.sub.1 -.sub.4)alkyl, 2,2,2-trichloroethyl, acetonyl, benzyl, benzyl substituted by nitro or methoxy, phenyl, nitrophenyl, benzhydryl or trimethylsilyl;R' may also represent a radical capable of providing metabolic activation in vivo selected from acetoxymethyl, pivaloyloxymethyl, phthalidyl, benzoyloxymethyl, 5-indanyl, a group of formula ##STR2## or a group of formula ##STR3## in which R" stands for (C.sub.1 -.sub.4)alkyl, (C.sub.5 -.sub.6)cycloalkyl or aryl; n may be zero or 1.The compounds possess antibacterial utility against microbial infections in man, animals and plants.
    Type: Grant
    Filed: July 1, 1981
    Date of Patent: June 21, 1983
    Assignee: Ausonia Farmaceutici s.r.l.
    Inventors: Michele Di Schiena, Vittoria Orru
  • Patent number: 4387096
    Abstract: New derivatives of 1,3-thiazolidin-4-yl carboxylic acid of the general formula I ##STR1## wherein: R represents hydrogen, (C.sub.1-4)alkyl,aralkyl, phenyl, phenyl substituted by a halogen atom or a methoxy group, formyl, acyl, trimethylsilyl;R' represents hydrogen, a pharmaceutically acceptable inorganic or organic cation, (C.sub.1-4)alkyl, 2,2,2-trichloroethyl, acetonly, benzyl, benzyl substituted by nitro or methoxy, phenyl, nitrophenyl, benzhydryl or trimethylsilyl;R' may also represent a radical capable of providing metabolic activation in vivo selected from acetoxymethyl, pivaloyloxymethyl, phthalidyl, benzoyloxymethyl, 5-indanyl, a group of formula ##STR2## or a group of formula ##STR3## in which R" stands for (C.sub.1-4)alkyl, (C.sub.5-6)cycloalkyl or aryl; A represents hydrogen, halogen, N.sub.3, OH, NH.sub.2 ; or a quaternary N-atom, particularly ##STR4## in this case R' is a negative charge); or a O--CO--NH.sub.2 group; or a group of the formula OR"', O--COR"', NH--CO--R"' or SR"', where R"' is (C.
    Type: Grant
    Filed: July 1, 1981
    Date of Patent: June 7, 1983
    Assignee: Ausonia Farmaceutici s.r.l.
    Inventors: Michele di Schiena, Vittoria Orru