Patents by Inventor Michele Fiscella

Michele Fiscella has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HXAAA01 Polynucleotides
    Publication number: 20090203635
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: January 3, 2008
    Publication date: August 13, 2009
    Inventors: Craig A. Rosen, George A. Komatsoulis, Kevin P. Baker, Michele Fiscella, Paul A. Moore, Ping Wei, D. Roxanne Duan, Yanggu Shi, Ram Gupta
  • 157 human secreted proteins
    Publication number: 20060073561
    Abstract: The present invention relates to human secreted polypeptides, and isolated nucleic acid molecules encoding said polypeptides, useful for diagnosing and treating diseases, disorders, and/or conditions related to said human secreted proteins. Antibodies that bind these polypeptides are also encompassed by the present invention. Also encompassed by the invention are vectors, host cells, and recombinant and synthetic methods for producing said polynucleotides, polypeptides, and/or antibodies. The invention further encompasses screening methods for identifying agonists and antagonists of polynucleotides and polypeptides of the invention. The present invention further encompasses methods and compositions for inhibiting or enhancing the production and function of the polypeptides of the present invention.
    Type: Application
    Filed: November 12, 2004
    Publication date: April 6, 2006
    Inventors: Craig Rosen, Steven Ruben, Henrik Olsen, Kevin Baker, Michele Fiscella, Ping Wei, Charles Birse, George Komatsoulis, Gil Choi, Paul Moore, Ram Gupta, Yanggu Shi
  • 26 human secreted proteins
    Publication number: 20050214786
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: August 19, 2004
    Publication date: September 29, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: Charles Birse, George Komatsoulis, Gil Choi, Henrik Olsen, Jian Ni, Kevin Baker, Craig Rosen, Steven Ruben, Michele Fiscella, Paul Moore, Ping Wei
  • 89 human secreted proteins
    Publication number: 20050208602
    Abstract: The present invention relates to human secreted polypeptides, and isolated nucleic acid molecules encoding said polypeptides, useful for diagnosing and treating diseases, disorders, and/or conditions related to said human secreted proteins. Antibodies that bind these polypeptides are also encompassed by the present invention. Also encompassed by the invention are vectors, host cells, and recombinant and synthetic methods for producing said polynucleotides, polypeptides, and/or antibodies. The invention further encompasses screening methods for identifying agonists and antagonists of polynucleotides and polypeptides of the invention. The present invention further encompasses methods and compositions for inhibiting or enhancing the production and function of the polypeptides of the present invention.
    Type: Application
    Filed: February 9, 2004
    Publication date: September 22, 2005
    Inventors: Craig Rosen, Kevin Baker, Charles Birse, Gil Choi, Michele Fiscella, George Komatsoulis, Paul Moore, Jian Ni, Henrik Olsen, Steven Ruben, Ping Wei, D. Roxanne Duan, Yanggu Shi
  • Secreted protein HCE3C63
    Patent number: 6936691
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Grant
    Filed: April 11, 2001
    Date of Patent: August 30, 2005
    Assignee: Human Genome Sciences, Inc.
    Inventors: Michele Fiscella, Ping Wei, David W. LaFleur, Henrik S. Olsen, Kevin P. Baker, Reinhard Ebner, George A. Komatsoulis, Craig A. Rosen, Steven M. Ruben, Roxanne D. Duan, Paul E. Young, Kimberly A. Florence, Paul A. Moore, Charles E. Birse, Jian Ni, Daniel R. Soppet, Yanggu Shi
  • 70 human secreted proteins
    Publication number: 20050181371
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: August 21, 2003
    Publication date: August 18, 2005
    Inventors: Craig Rosen, George Komatsoulis, Kevin Baker, Michele Fiscella, Paul Moore, Ping Wei, D. Duan, Yanggu Shi, Ram Gupta
  • 17 human secreted proteins
    Publication number: 20050032168
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: July 23, 2004
    Publication date: February 10, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: Craig Rosen, George Komatsoulis, Kevin Baker, Charles Birse, Daniel Soppet, Henrik Olsen, Paul Moore, Ping Wei, Reinhard Ebner, D. Duan, Yanggu Shi, Gil Choi, Michele Fiscella, Jian Ni, Steven Ruben, Steven Barash
  • 52 Human secreted proteins
    Publication number: 20050019866
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: July 6, 2004
    Publication date: January 27, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Kevin Baker, Charles Birse, Michele Fiscella, George Komatsoulis, Craig Rosen, Daniel Soppet, Paul Young, Reinhard Ebner, D. Duan, Henrik Olsen, David La Fleur, Paul Moore, Yanggu Shi, Ping Wei, Kimberly Florence
  • 25 human secreted proteins
    Publication number: 20040241803
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: July 1, 2004
    Publication date: December 2, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Craig A. Rosen, Jian Ni, Kimberly A. Florence, Michele Fiscella, Ping Wei, Kevin P. Baker, Charles E. Birse, Paul E. Young, George A. Komatsoulis, Paul A. Moore, Daniel R. Soppet
  • 19 human secreted proteins
    Publication number: 20040126801
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: December 12, 2003
    Publication date: July 1, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Michele Fiscella, Ping Wei, David W. LaFleur, Henrik S. Olsen, Kevin P. Baker, Reinhard Ebner, George A. Komatsoulis, Craig A. Rosen, Steven M. Ruben, D. Roxanne Duan, Paul E. Young, Kimberly A. Florence, Paul A. Moore, Charles E. Birse, Jian Ni, Daniel R. Soppet, Yanggu Shi
  • B7-like polypeptides and polynucleotides
    Publication number: 20030208058
    Abstract: The present invention relates to novel human B7-like polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human B7-like polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human B7-like polypeptides.
    Type: Application
    Filed: December 20, 2001
    Publication date: November 6, 2003
    Applicant: Human Genome Sciences, Inc.
    Inventors: Michele Fiscella, Jian Ni, Steven M. Ruben
  • 17 human secreted proteins
    Publication number: 20030190707
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: October 23, 2002
    Publication date: October 9, 2003
    Inventors: Craig A. Rosen, George A. Komatsoulis, Kevin P. Baker, Charles E. Birse, Daniel R. Soppet, Henrik S. Olsen, Paul A. Moore, Ping Wei, Reinhard Ebner, D. Roxanne Duan, Yanggu Shi, Gil H. Choi, Michele Fiscella, Jian Ni, Steven M. Ruben, Steven C. Barash
  • Protein HOFNF53
    Patent number: 6605592
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. In particular, the present application relates to a novel human protein, Protein HOFNF53. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Grant
    Filed: March 8, 2001
    Date of Patent: August 12, 2003
    Assignee: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Kevin P. Baker, Charles E. Birse, Reinhard Ebner, Michele Fiscella, George A. Komatsoulis, David W. LaFleur, Paul A. Moore, Henrik S. Olsen, Craig A. Rosen, Steven M. Ruben, Daniel R. Soppet, Paul E. Young, Ping Wei, Kimberly A. Florence
  • 25 human secreted proteins
    Publication number: 20030113840
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: February 1, 2002
    Publication date: June 19, 2003
    Applicant: Human Genome Sciences, Inc.
    Inventors: Craig A. Rosen, Jian Ni, Kimberly A. Florence, Michele Fiscella, Ping Wei, Kevin P. Baker, Charles E. Birse, Paul E. Young, George A. Komatsoulis, Paul A. Moore, Daniel R. Soppet
  • 19 human secreted proteins
    Publication number: 20030027297
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: April 11, 2001
    Publication date: February 6, 2003
    Inventors: Michele Fiscella, Ping Wei, David W. LaFleur, Henrik S. Olsen, Kevin P. Baker, Reinhard Ebner, George A. Komatsoulis, Craig A. Rosen, Steven M. Ruben, Roxanne D. Duan, Paul E. Young, Kimberly A. Florence, Paul A. Moore, Charles E. Birse, Jian Ni, Daniel R. Soppet, Yanggu Shi
  • 17 human secreted proteins
    Publication number: 20020120103
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: July 27, 2001
    Publication date: August 29, 2002
    Inventors: Craig A. Rosen, George A. Komatsoulis, Kevin P. Baker, Charles E. Birse, Daniel R. Soppet, Henrik S. Olsen, Paul A. Moore, Ping Wei, Reinhard Ebner, D. Roxanne Duan, Yanggu Shi, Gil H. Choi, Michele Fiscella, Jian Ni, Steven M. Ruben, Steven C. Barash
  • Extracellular matrix polynucleotides, polypeptides, and antibodies
    Publication number: 20020106780
    Abstract: The present invention relates to novel human extracellular matrix polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human extracellular matrix polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human extracellular matrix polypeptides.
    Type: Application
    Filed: October 17, 2001
    Publication date: August 8, 2002
    Inventors: Michele Fiscella, Reinhard Ebner, Yanggu Shi, Steven M. Ruben
  • 32 human secreted proteins
    Publication number: 20020068319
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: March 8, 2001
    Publication date: June 6, 2002
    Inventors: Jian Ni, Kevin P. Baker, Charles E. Birse, Reinhard Ebner, Michele Fiscella, George A. Komatsoulis, David W. LaFleur, Paul A. Moore, Henrik S. Olsen, Craig A. Rosen, Steven M. Ruben, Daniel R. Soppet, Paul E. Young, Ping Wei, Kimberly A. Florence
  • 52 human secreted proteins
    Publication number: 20020064818
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: February 22, 2001
    Publication date: May 30, 2002
    Inventors: Jian Ni, Kevin P. Baker, Charles E. Birse, Michele Fiscella, George A. Komatsoulis, Craig A. Rosen, Daniel R. Soppet, Paul E. Young, Reinhard Ebner, D. Roxanne Duan, Henrik S. Olsen, David W. LaFleur, Paul A. Moore, Yanggu Shi, Ping Wei, Kimberly A. Florence