Patents by Inventor Michele Pierro

Michele Pierro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230389800
    Abstract: A contactless system for assessing tissue viability and other hemodynamic parameters includes one or more light sources configured to emit lights at a predetermined wavelength sensitive to hemoglobin concentration associated with spontaneous hemodynamic oscillations at tissue in a predetermined area of a human subject. One or more polarizers are each coupled to one or more of the one or more light sources and are configured to polarize the light to a polarized state such that the polarized light in the polarized state diffuses into the tissue in the predetermined area at a predetermined depth and the polarized light is maintained in the polarized state at the predetermined depth. One or more detectors each including a detector polarizer coupled thereto are configured to discriminate the light maintained in the polarized state and at the predetermined depth and are configured to generate a plurality of frames of the tissue in the predetermined area at the predetermined depth.
    Type: Application
    Filed: August 2, 2023
    Publication date: December 7, 2023
    Inventors: Michele Pierro, Kyle Quinn, Alan Woessner
  • Patent number: 11426076
    Abstract: A contactless system for assessing and/or determining hemodynamic parameters and/or vital signs is featured. The system includes one or more contactless light sources configured to emit light incident on a moving living subject at one more wavelengths absorbed by one or more chromophores associated with spontaneous hemodynamic oscillations in a predetermined area of the living subject. The system includes a camera subsystem including one or more cameras configured to receive reflected light from the predetermined area of the moving living subject and configured to track motion of the predetermined area of the living subject within a field of view of the camera subsystem and configured to generate a time sequence of images of the predetermined area of the living subject.
    Type: Grant
    Filed: November 25, 2020
    Date of Patent: August 30, 2022
    Assignee: Vivonics, Inc.
    Inventor: Michele Pierro
  • Patent number: 11350825
    Abstract: A contactless system for measuring and continuously monitoring arterial blood pressure includes a light source configured to illuminate light having at least one predetermined wavelength at a predetermined area of a human subject having an artery therein. A detector responsive to reflected light from the predetermined area to continuously acquire images of the artery in the predetermined area. A processor processes the images and determines when an image at a proximal location of the predetermined area is darker indicating transition of a pulse wave into the artery at the proximal location and at a proximal time and when an image at a distal location of the predetermined area is darker indicating transition of the pulse wave into the artery at a distal location at a distal time to contactlessly and continuously calculate the arterial blood pressure for each cardiac cycle of the human subject.
    Type: Grant
    Filed: August 24, 2017
    Date of Patent: June 7, 2022
    Assignee: Vivonics, Inc.
    Inventor: Michele Pierro
  • Publication number: 20210361181
    Abstract: A system for non-invasively determining an indication and/or an assessment of intracranial pressure (ICP) is featured. The system includes at least one intracranial light source adapted to be placed on skin above a cranium of a living subject configured to emit light which penetrates the cranium and targets intracranial space of a living subject. The system includes a least one extracranial light source adapted to be placed on skin above a predetermined area of the living subject configured to emit light which penetrates and targets extracranial space of the living subject. A detector subsystem including at least a first detector is configured to detect reflected light from the intracranial space and the extracranial space and is configured to output intracranial output signals associated with light detected from the intracranial space and/or output extracranial output signals associated with light detected from the extracranial space.
    Type: Application
    Filed: August 6, 2021
    Publication date: November 25, 2021
    Inventor: Michele Pierro
  • Patent number: 11109771
    Abstract: A system for non-invasively determining an indication and/or an assessment of intracranial pressure (ICP) is featured. The system includes at least one intracranial light source adapted to be placed on skin above a cranium of a living subject configured to emit light which penetrates the cranium and targets intracranial space of a living subject. The system includes at least one extracranial light source adapted to be placed on skin above a predetermined area of the living subject configured to emit light which penetrates and targets extracranial space of the living subject. A detector subsystem including at least a first detector is configured to detect reflected light from the intracranial space and the extracranial space and is configured to output intracranial output signals associated with light detected from the intracranial space and/or output extracranial output signals associated with light detected from the extracranial space.
    Type: Grant
    Filed: December 31, 2020
    Date of Patent: September 7, 2021
    Assignee: Vivonics, Inc.
    Inventor: Michele Pierro
  • Publication number: 20210204826
    Abstract: A system for non-invasively determining an indication and/or an assessment of intracranial pressure (ICP) is featured. The system includes at least one intracranial light source adapted to be placed on skin above a cranium of a living subject configured to emit light which penetrates the cranium and targets intracranial space of a living subject. The system includes at least one extracranial light source adapted to be placed on skin above a predetermined area of the living subject configured to emit light which penetrates and targets extracranial space of the living subject. A detector subsystem including at least a first detector is configured to detect reflected light from the intracranial space and the extracranial space and is configured to output intracranial output signals associated with light detected from the intracranial space and/or output extracranial output signals associated with light detected from the extracranial space.
    Type: Application
    Filed: December 31, 2020
    Publication date: July 8, 2021
    Inventor: Michele Pierro
  • Publication number: 20210153744
    Abstract: A contactless system for assessing and/or determining hemodynamic parameters and/or vital signs is featured. The system includes one or more contactless light sources configured to emit light incident on a moving living subject at one more wavelengths absorbed by one or more chromophores associated with spontaneous hemodynamic oscillations in a predetermined area of the living subject. The system includes a camera subsystem including one or more cameras configured to receive reflected light from the predetermined area of the moving living subject and configured to track motion of the predetermined area of the living subject within a field of view of the camera subsystem and configured to generate a time sequence of images of the predetermined area of the living subject.
    Type: Application
    Filed: November 25, 2020
    Publication date: May 27, 2021
    Inventor: Michele Pierro
  • Publication number: 20210076958
    Abstract: A system for non-invasively measuring blood volume oscillations inside a cranium of a human subject. The system includes a first light source adapted to be placed on the skin above the cranium of the human subject configured to emit light which penetrates a superficial space outside the cranium. A detector is adapted to be placed on the skin above the cranium of the human subject spaced from the first light source by a first predetermined separation distance that causes the detector to detect light which reflects from the superficial space outside the cranium and output superficial output signals. A second light source is adapted be placed on the skin above the cranium configured to emit light which penetrates through the superficial space outside the cranium to inside the cranium and the detector is spaced from the second light source by a second predetermined separation distance that causes the detector to detect light which reflects from inside the cranium and output cranial output signals.
    Type: Application
    Filed: September 10, 2020
    Publication date: March 18, 2021
    Inventors: Michele Pierro, Gordon B. Hirschman
  • Patent number: 10448835
    Abstract: A contactless system for assessing tissue viability and other hemodynamic parameters includes one or more light sources configured to emit lights at a predetermined wavelength sensitive to hemoglobin concentration associated with spontaneous hemodynamic oscillations at tissue in a predetermined area of a human subject. One or more polarizers are each coupled to one or more of the one or more light sources and are configured to polarize the light to a polarized state such that the polarized light in the polarized state diffuses into the tissue in the predetermined area at a predetermined depth and the polarized light is maintained in the polarized state at the predetermined depth. One or more detectors each including a detector polarizer coupled thereto are configured to discriminate the light maintained in the polarized state and at the predetermined depth and are configured to generate a plurality of frames of the tissue in the predetermined area at the predetermined depth.
    Type: Grant
    Filed: January 4, 2019
    Date of Patent: October 22, 2019
    Assignees: Vivonics, Inc., The Board of Trustees of The University of Arkansas
    Inventors: Michele Pierro, Kyle Quinn, Alan Woessner
  • Publication number: 20190223730
    Abstract: A contactless system for assessing tissue viability and other hemodynamic parameters includes one or more light sources configured to emit lights at a predetermined wavelength sensitive to hemoglobin concentration associated with spontaneous hemodynamic oscillations at tissue in a predetermined area of a human subject. One or more polarizers are each coupled to one or more of the one or more light sources and are configured to polarize the light to a polarized state such that the polarized light in the polarized state diffuses into the tissue in the predetermined area at a predetermined depth and the polarized light is maintained in the polarized state at the predetermined depth. One or more detectors each including a detector polarizer coupled thereto are configured to discriminate the light maintained in the polarized state and at the predetermined depth and are configured to generate a plurality of frames of the tissue in the predetermined area at the predetermined depth.
    Type: Application
    Filed: January 4, 2019
    Publication date: July 25, 2019
    Inventors: Michele Pierro, Kyle Quinn, Alan Woessner
  • Publication number: 20180055364
    Abstract: A contactless system for measuring and continuously monitoring arterial blood pressure includes a light source configured to illuminate light having at least one predetermined wavelength at a predetermined area of a human subject having an artery therein. A detector responsive to reflected light from the predetermined area is configured to continuously acquire images of the artery in the predetermined area.
    Type: Application
    Filed: August 24, 2017
    Publication date: March 1, 2018
    Inventor: Michele Pierro
  • Patent number: RE49639
    Abstract: A contactless system for assessing tissue viability and other hemodynamic parameters includes one or more light sources configured to emit lights at a predetermined wavelength sensitive to hemoglobin concentration associated with spontaneous hemodynamic oscillations at tissue in a predetermined area of a human subject. One or more polarizers are each coupled to one or more of the one or more light sources and are configured to polarize the light to a polarized state such that the polarized light in the polarized state diffuses into the tissue in the predetermined area at a predetermined depth and the polarized light is maintained in the polarized state at the predetermined depth. One or more detectors each including a detector polarizer coupled thereto are configured to discriminate the light maintained in the polarized state and at the predetermined depth and are configured to generate a plurality of frames of the tissue in the predetermined area at the predetermined depth.
    Type: Grant
    Filed: October 28, 2020
    Date of Patent: September 5, 2023
    Assignee: Vivonics, Inc.
    Inventors: Michele Pierro, Kyle Quinn, Alan Woessner