Patents by Inventor Michelle Akerman

Michelle Akerman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds, pharmaceutical compositions and methods for use in treating metabolic disorders
    Patent number: 7816367
    Abstract: The present invention provides compounds useful, for example, for modulating insulin levels in a subject and that have the general formula Q-L1-P-L2-M-X-L3-A wherein the definitions of the variables Q, L1, P, L2, M, X, L3 and A are provided herein. The present invention also provides compositions and methods for use of the compounds, for instance, for treatment of type II diabetes.
    Type: Grant
    Filed: February 24, 2005
    Date of Patent: October 19, 2010
    Assignee: Amgen Inc.
    Inventors: Michelle Akerman, Jonathan Houze, Daniel C. H. Lin, Jiwen Liu, Jian Luo, Julio C. Medina, Wei Qiu, Jeffrey D. Reagan, Rajiv Sharma, Stephen J. Shuttleworth, Ying Sun, Jian Zhang, Liusheng Zhu, Jinqian Liu, Zhihua Ma, Yingcai Wang, Michael J. Schmitt
  • Compounds, pharmaceutical compositions and methods for use in treating metabolic disorders
    Patent number: 7649110
    Abstract: The present invention provides compounds useful, for example, for modulating insulin levels in a subject and that have the general formula Q—L1—P—L2—M—X—L3—A wherein the definitions of the variables Q, L1, P, L2, M, X, L3 and A are provided herein. The present invention also provides compositions and methods for use of the compounds, for instance, for treatment of type II diabetes.
    Type: Grant
    Filed: February 25, 2005
    Date of Patent: January 19, 2010
    Assignee: Amgen Inc.
    Inventors: Michelle Akerman, Jonathan Houze, Daniel C. H. Lin, Jinqian Liu, Jiwen Liu, Jian Luo, Zhihua Ma, Julio C. Medina, Wei Qiu, Jeffrey D. Reagan, Rajiv Sharma, Michael J. Schmitt, Stephen J. Shuttleworth, Ying Sun, Yingcai Wang, Jian Zhang, Liusheng Zhu
  • Conformationally constrained 3-(4-hydroxy-phenyl)-substituted-propanoic acids useful for treating metabolic disorders
    Publication number: 20090275598
    Abstract: The present invention provides compounds useful, for example, for treating metabolic disorders in a subject. Such compounds have the general formula I: where the definitions of the variables Q, L1, L2, M, X, L3, and A are provided herein. The present invention also provides compositions that include, and methods for using, the compounds in preparing medicaments and for treating metabolic disorders such as, for example, type II diabetes.
    Type: Application
    Filed: July 10, 2009
    Publication date: November 5, 2009
    Applicant: Amgen Inc.
    Inventors: Michelle Akerman, Sean Brown, Jonathan B. Houze, Jinqian Liu, Jiwen Liu, Zhihua Ma, Julio C. Medina, Wei Qiu, Michael J. Schmitt, Rajiv Sharma, Yingcai Wang, Liusheng Zhu
  • Conformationally constrained 3-(4-hydroxy-phenyl)-substituted-propanoic acids useful for treating metabolic disorders
    Patent number: 7582803
    Abstract: The present invention provides compounds useful, for example, for treating metabolic disorders in a subject. Such compounds have the general formula I: where the definitions of the variables Q, L1, L2, M, X, L3, and A are provided herein. The present invention also provides compositions that include, and methods for using, the compounds in preparing medicaments and for treating metabolic disorders such as, for example, type II diabetes.
    Type: Grant
    Filed: September 8, 2006
    Date of Patent: September 1, 2009
    Assignee: Amgen Inc.
    Inventors: Michelle Akerman, Sean Brown, Jonathan B. Houze, Jinqian Liu, Jiwen Liu, Zhihua Ma, Julio C. Medina, Wei Qiu, Michael J. Schmitt, Yingcai Wang, Liusheng Zhu, Rajiv Sharma
  • Bicyclic carboxylic acid derivatives useful for treating metabolic disorders
    Publication number: 20070244155
    Abstract: Compounds having the general formula I and/or the general formula II are useful, for example, for treating metabolic disorders in a subject where the variables are provided herein. Compositions and methods for using the compounds for preparing medicaments and for treating metabolic disorders such as, for instance, type II diabetes are disclosed.
    Type: Application
    Filed: March 13, 2007
    Publication date: October 18, 2007
    Applicant: AMGEN INC.
    Inventors: Rajiv Sharma, Michelle Akerman, Mario Cardozo, Jonathan Houze, An-Rong Li, Jinquian Liu, Jiwen Liu, Zhihua Ma, Julio Medina, Michael Schmitt, Ying Sun, Yingcai Wang, Zhongyu Wang, Liusheng Zhu
  • Compounds, pharmaceutical compositions and methods for use in treating metabolic disorders
    Publication number: 20070142384
    Abstract: The present invention provides compounds useful, for example, for modulating insulin levels in a subject and that have the general formula Q-L1-P-L2-M-X-L3-A wherein the definitions of the variables Q, L1, P, L2, M, X, L3 and A are provided herein. The present invention also provides compositions and methods for use of the compounds, for instance, for treatment of type II diabetes.
    Type: Application
    Filed: February 24, 2005
    Publication date: June 21, 2007
    Applicant: AMGEN INC.
    Inventors: Michelle Akerman, Jonathan Houze, Daniel Lin, Jinqian Liu, Jiwen Liu, Jian Luo, Zhihua Ma, Julio Medina, Wei Qiu, Jeffrey Reagan, Rajiv Sharma, Michael Schmitt, Stephen Shuttleworth, Ying Sun, Yingcai Wang, Jian Zhang, Liusheng Zhu
  • Conformationally constrained 3-(4-hydroxy-phenyl)-substituted-propanoic acids useful for treating metabolic disorders
    Publication number: 20070066647
    Abstract: The present invention provides compounds useful, for example, for treating metabolic disorders in a subject. Such compounds have the general formula I: where the definitions of the variables Q, L1, L2, M, X, L3, and A are provided herein. The present invention also provides compositions that include, and methods for using, the compounds in preparing medicaments and for treating metabolic disorders such as, for example, type II diabetes.
    Type: Application
    Filed: September 8, 2006
    Publication date: March 22, 2007
    Applicant: AMGEN ING.
    Inventors: Michelle Akerman, Sean Brown, Jonathan Houze, Jinqian Liu, Jiwen Liu, Zhihua Ma, Julio Medina, Wei Qiu, Michael Schmitt, Rajiv Sharma, Yingcai Wang, Liusheng Zhu
  • Compounds, pharmaceutical compositions and methods for use in treating metabolic disorders
    Publication number: 20060004012
    Abstract: The present invention provides compounds useful, for example, for modulating insulin levels in a subject and that have the general formula Q-L1-P-L2-M-X-L3-A wherein the definitions of the variables Q, L1, P, L2, M, X, L3 and A are provided herein. The present invention also provides compositions and methods for use of the compounds, for instance, for treatment of type II diabetes.
    Type: Application
    Filed: February 25, 2005
    Publication date: January 5, 2006
    Inventors: Michelle Akerman, Jonathan Houze, Daniel Lin, Jiwen Liu, Jian Luo, Julio Medina, Wei Qiu, Jeffrey Reagan, Rajiv Sharma, Michael Schmitt, Stephen Shuttleworth, Ying Sun, Yingcai Wang, Jian Zhang, Liusheng Zhu