Abstract: Medical systems, devices and methods are provided for engaging tissue, e.g. for clipping tissue, closing a perforation or performing hemostasis. Generally, the medical system including a housing, first and second jaws rotatable relative to the housing, a driver, and an elongate drive wire. The elongate drive wire may be disconnected from the driver, first and second jaws, and the housing, which are left in vivo engaged with the tissue.

Abstract: The exemplary embodiments illustrated provide the discovery of methods and apparatuses for periscope devices that couple to a viewing end of a visualization catheter or endoscope to extend the viewing range and accessory range of the endoscope or visualization catheter so as to provide for greater viewing and reach into multiple areas of the anatomy.

Abstract: A valve insertion device for traversing a wire guide through a valve within an intraluminal passage. A wire guide is positioned near the outflow of a valve within an intraluminal passage. Alongside the wire guide, a pressure sensor is positioned to detect the pressure of the fluid in the intraluminal passage. As the valve opens, the fluid pressure at the outflow of the valve increases. This information is sent from the pressure sensor to a control system. From this information, the control system can determine when the valve will open and can actuate an advancement system to move the wire guide to traverse the open valve. After traversing the valve, various catheters and sheaths may be advanced over the wire guide through the valve.

Abstract: The present embodiments provide systems and methods for deploying at least one clip device. In a first embodiment, the system comprises a first clip device having first and second arms. The first clip device and an associated sliding ring are configured to be selectively advanced through a lumen of an inner catheter. Selective positioning of an outer catheter over a distal region of the inner catheter causes a distal region of the inner catheter to bow radially inward to form a constriction that securely engages the sliding ring of the first clip device, thereby allowing for partial closure and repositioning of the first clip device. In an alternative embodiment, a delivery system includes a single catheter having a tapered distal region, such that upon ejection of the sliding ring from the distal end of the catheter, the sliding ring is dimensioned to abut the distal end of the catheter. In any of the embodiments, multiple clips may be sequentially loaded and deployed using the delivery systems.

Abstract: Medical systems, devices and methods are provided for engaging tissue, e.g. for clipping tissue, closing a perforation or performing hemostasis. Generally, the medical system including a housing, first and second jaws rotatable relative to the housing, a driver, and an elongate drive wire. The elongate drive wire may be disconnected from the driver, first and second jaws, and the housing, which are left in vivo engaged with the tissue.

Abstract: Medical systems, devices and methods are provided for engaging tissue, e.g. for clipping tissue, closing a perforation or performing hemostasis. Generally, the medical system including a housing, first and second jaws rotatable relative to the housing, first and second links attached to both the jaws and the housing, and a driver. The housing, first and second jaws, and first and second links form a linkage mechanism that allows the jaws to engage tissue and be left in vivo.

Abstract: An endovascular delivery system for forming a magnetic compression vascular anastomosis includes a first compressing element and a first catheter configured for advancement into a first cardiovascular structure. In one configuration, the first compressing element is removably secured within the first catheter and, in another configuration, the first compressing element is released from the first catheter and positioned within the first cardiovascular structure. The endovascular delivery system also includes a second compressing element and a second catheter configured for advancement into a second cardiovascular structure. In one configuration, the second compressing element is removably secured within the second catheter and, in another configuration, the second compressing element is released from the second catheter and positioned within the second cardiovascular structure.

Abstract: Medical systems, devices and methods are provided for engaging tissue, e.g. for clipping tissue, closing a perforation or performing hemostasis. Generally, the medical system including a housing, first and second jaws rotatable relative to the housing, a driver, and an elongate drive wire. The elongate drive wire may be disconnected from the driver, first and second jaws, and the housing, which are left in vivo engaged with the tissue.

Abstract: Medical systems, devices and methods are provided for engaging tissue, e.g. for clipping tissue, closing a perforation or performing hemostasis. Generally, the medical system including a housing, first and second jaws rotatable relative to the housing, a driver, and an elongate drive wire. The elongate drive wire may be disconnected from the driver, first and second jaws, and the housing, which are left in vivo engaged with the tissue. The medical device of the system may include a biasing strip engaged with the jaws, and/or a gripping strip attached to at least one of the jaws to improve the engagement of the tissue between the jaws.

Abstract: Medical systems, devices and methods are provided for engaging tissue, e.g. for clipping tissue, closing a perforation or performing hemostasis. Generally, the medical system including a housing, first and second jaws rotatable relative to the housing, first and second links pivotally attached to the jaws, and a driver. The housing, first and second jaws, and first and second links form a linkage mechanism that allows the jaws to engage tissue and be left in vivo.

Abstract: Medical systems, devices and methods are provided for engaging tissue, e.g. for clipping tissue, closing a perforation or performing hemostasis. Generally, the medical system including a housing, first and second jaws rotatable relative to the housing, a driver, and an elongate drive wire. The elongate drive wire may be disconnected from the driver, first and second jaws, and the housing, which are left in vivo engaged with the tissue.

Abstract: A left atrial appendage shunt for reducing blood clot formation in a left atrial appendage includes a first artificially created opening through a wall of the left atrial appendage and a second artificially created opening through a wall of a target cardiovascular structure. A circulation conduit fluidly connects an interior of the left atrial appendage and an interior of the target cardiovascular structure, and has a first end opening at the first artificially created opening and a second end opening at the second artificially created opening.

Abstract: Medical systems, devices and methods are provided for engaging tissue, e.g. for clipping tissue, closing a perforation or performing hemostasis. Generally, the medical system including a housing, first and second jaws rotatable relative to the housing, a driver, and an elongate drive wire. The elongate drive wire may be disconnected from the driver, first and second jaws, and the housing, which are left in vivo engaged with the tissue.

Abstract: A bipolar sphincterotome may include an elongate tubular member, a cutting wire, and a return path. The return path may include a conductive ink portion disposed on an outer surface at a distal portion of the tubular member. The return path may also include a return wire disposed within the tubular member that is electrically coupled to the conductive ink portion. In some example embodiments, the return wire may be disposed within a lumen configured to have two or more functions, one of which being to house the return wire. Additionally, in some example embodiments, the conductive ink portion may be circumferentially disposed on the outer surface to provide visual access to a wire guide lumen. Also, for some example embodiments, the bipolar sphincterotome may include two electrically isolated return paths.

Abstract: A flexible lens is mounted to the end of an elongate medical device having a camera, such as an endoscope. The lens is generally solid and is made from a translucent, flexible, and resilient material. In a medical environment, the lens can be pressed against a vessel wall in a patient to enlarge the area viewed by the camera, and can further adapt to the shape of the wall to limit trauma on the patient. When pressed against the vessel wall, the lens can become longitudinally compressed, while becoming wider. The wider and compressed shape of the lens will push blood away from the viewing area to increase the clarity of the camera's field of view.

Abstract: Medical systems, devices and methods are provided for engaging tissue, e.g. for clipping tissue, closing a perforation or performing hemostasis. Generally, the medical system including a housing, first and second jaws rotatable relative to the housing, a driver, and an elongate drive wire. The elongate drive wire may be disconnected from the driver, first and second jaws, and the housing, which are left in vivo engaged with the tissue.

Abstract: A hemostatic clipping device is provided. The device includes first and second elongate arms, each arm comprising distal and proximal end portions, the arms being connected to allow relative motion between the first and second arms, the distal portion of each of the first and second arms further comprising a track blindly defined from a distal end of each arm toward the proximal portion of each arm. A clip is slidably disposed between the opposed distal portions of each of the first and second arms, the clip comprising first and second fingers each with distal and proximal portions, the proximal portions of the first and second fingers being fixed together to bias the distal portions of the first and second fingers toward each other, the first and second fingers each further comprising a pin extending radially outward from the distal end portion thereof.

Abstract: A sphincterotome having a pair of ribs that are disposed equidistant from each other about an outer surface of a tubular member of the sphincterotome is disclosed. The pair of ribs is oriented perpendicular to a radial direction in which a cutting edge of a cutting wire disposed at a distal portion of the tubular member extends.

Abstract: A medical system generally comprises a camera head, a beam, and a guide sheath. The camera head is connected to the beam which is bendable in a first direction and resists bending in a second direction opposite the first direction. The guide sheath slidably receives the beam, the beam extending through a distal end of the guide sheath such that the camera head projects from the distal end of the guide sheath. The guide sheath includes first and second sheath portions, and in an operative configuration the first sheath portion is angled relative to the second sheath portion to define a first bend. The beam is oriented relative to the guide sheath such that, as the beam is slid relative to guide sheath, the beam bends in the first direction through the first bend, and a projecting portion of the beam resists bending in the second direction.

Abstract: Medical systems, devices and methods are provided for engaging tissue, e.g. for clipping tissue, closing a perforation or performing hemostasis. Generally, the medical system including a housing, first and second jaws rotatable relative to the housing, first and second links attached to both the jaws and the housing, and a driver. The housing, first and second jaws, and first and second links form a linkage mechanism that allows the jaws to engage tissue and be left in vivo.