Patents by Inventor Michelle M. Grilley

Michelle M. Grilley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Conotoxin peptides
    Patent number: 5739276
    Abstract: The present invention is directed to .delta.-conotoxin PVIA having the formula Glu-Ala-Cys-Tyr-Ala-Xaa.sub.1 -Gly-Thr-Phe-Cys-Gly-Ile-Lys-Xaa.sub.2 -Gly-Leu-Cys-Cys-Ser-Glu-Phe-Cys-Leu-Pro-Gly-Val-Cys-Pro-Gly (Xaa.sub.1 or Xaa.sub.2 is Pro or 4-trans-hydroxyproline) (SEQ ID NO:7). The C-terminus may be free or amidated. This latter conotoxin is vertebrate-specific which targets voltage-sensitive Na channels.
    Type: Grant
    Filed: March 29, 1996
    Date of Patent: April 14, 1998
    Assignee: University of Utah Research Foundation
    Inventors: Ki-Joon Shon, Michelle M. Grilley, Baldomero M. Olivera