Patents by Inventor Michelle Thomas
Michelle Thomas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220289680Abstract: The present disclosure provides methods of preparing Compound of Formula (I), solid state forms of the same and compositions comprising the same. Also disclosed herein are methods of preparing a diacetate salt of Compound of Formula (I) and pharmaceutical compositions comprising the same.Type: ApplicationFiled: December 26, 2019Publication date: September 15, 2022Inventors: Kevin S. WARNER, Denis Viktorovich AREFYEV, Michael P. CRUSKIE, Chaminda Priyapushpa GAMAGE, Katherine Michelle THOMAS
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Patent number: 10898529Abstract: A method is provided of selecting specific probiotic lactic acid bacteria producing histamine and the use of such strains for beneficial effects for mammals. The method includes selecting a lactic acid bacterial strain for use in the local production of histamine in a mammal, and further comprises screening bacteria for the presence of an active histidine operon and selecting a strain which has an active histidine operon and is capable of producing histamine. Preferably said strain is selected for its ability to produce histamine at a level of greater than 250 pg/ml. The present invention further provides products comprising the strains obtainable by the selection methods of the invention for use in the local production of histamine in a mammal, in particular for use in the treatment or prophylaxis of inflammatory conditions.Type: GrantFiled: May 23, 2018Date of Patent: January 26, 2021Assignee: BIOGAIA ABInventors: James Versalovic, Carissa Michelle Thomas, Eamonn Connolly
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Publication number: 20180264055Abstract: A method is provided of selecting specific probiotic lactic acid bacteria producing histamine and the use of such strains for beneficial effects for mammals. The method includes selecting a lactic acid bacterial strain for use in the local production of histamine in a mammal, and further comprises screening bacteria for the presence of an active histidine operon and selecting a strain which has an active histidine operon and is capable of producing histamine. Preferably said strain is selected for its ability to produce histamine at a level of greater than 250 pg/ml. The present invention further provides products comprising the strains obtainable by the selection methods of the invention for use in the local production of histamine in a mammal, in particular for use in the treatment or prophylaxis of inflammatory conditions.Type: ApplicationFiled: May 23, 2018Publication date: September 20, 2018Inventors: James Versalovic, Carissa Michelle Thomas, Eamonn Connolly
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Patent number: 10004770Abstract: A method is provided of selecting specific probiotic lactic acid bacteria producing histamine and the use of such strains for beneficial effects for mammals. The method includes selecting a lactic acid bacterial strain for use in the local production of histamine in a mammal, and further comprises screening bacteria for the presence of an active histidine operon and selecting a strain which has an active histidine operon and is capable of producing histamine. Preferably said strain is selected for its ability to produce histamine at a level of greater than 250 pg/ml. The present invention further provides products comprising the strains obtainable by the selection methods of the invention for use in the local production of histamine in a mammal, in particular for use in the treatment or prophylaxis of inflammatory conditions.Type: GrantFiled: October 10, 2016Date of Patent: June 26, 2018Assignee: BIOGAIA ABInventors: James Versalovic, Carissa Michelle Thomas, Eamonn Connolly
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Publication number: 20170020936Abstract: A method is provided of selecting specific probiotic lactic acid bacteria producing histamine and the use of such strains for beneficial effects for mammals. The method includes selecting a lactic acid bacterial strain for use in the local production of histamine in a mammal, and further comprises screening bacteria for the presence of an active histidine operon and selecting a strain which has an active histidine operon and is capable of producing histamine. Preferably said strain is selected for its ability to produce histamine at a level of greater than 250 pg/ml. The present invention further provides products comprising the strains obtainable by the selection methods of the invention for use in the local production of histamine in a mammal, in particular for use in the treatment or prophylaxis of inflammatory conditions.Type: ApplicationFiled: October 10, 2016Publication date: January 26, 2017Inventors: James Versalovic, Carissa Michelle Thomas, Eamonn Connolly
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Publication number: 20130149291Abstract: A method is provided of selecting specific probiotic lactic acid bacteria producing histamine and the use of such strains for beneficial effects for mammals. The method includes selecting a lactic acid bacterial strain for use in the local production of histamine in a mammal, and further comprises screening bacteria for the presence of an. active histidine operon and selecting a strain which has an active histidine operon and is capable of producing histamine. Preferably said strain is selected for its ability to produce histamine at a level of greater than 250 pg/ml. The present invention further provides products comprising the strains obtainable by the selection methods of the invention for use in the local production, of histamine in a mammal, in particular for use in the treatment or prophylaxis of inflammatory conditions.Type: ApplicationFiled: February 13, 2013Publication date: June 13, 2013Inventors: James Versalovic, Carissa Michelle Thomas, Eamonn Connolly
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Publication number: 20130022586Abstract: A method is provided of selecting specific probiotic lactic acid bacteria producing histamine and the use of such strains for beneficial effects for mammals. The method includes selecting a lactic acid bacterial strain for use in the local production of histamine in a mammal, and further comprises screening bacteria for the presence of an active histidine operon and selecting a strain which has an active histidine operon and is capable of producing histamine. Preferably said strain is selected for its ability to produce histamine at a level of greater than 250 pg/ml. The present invention further provides products comprising the strains obtainable by the selection methods of the invention for use in the local production of histamine in a mammal, in particular for use in the treatment or prophylaxis of inflammatory conditions.Type: ApplicationFiled: July 19, 2012Publication date: January 24, 2013Inventors: James Versalovic, Carissa Michelle Thomas, Eamonn Connolly
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Patent number: 7977305Abstract: The present invention relates to hormone coating layers having desirable hormone delivery characteristics and product lifetime. In one embodiment, the invention is a hormone composition including a substrate having an external surface, and a coating layer disposed on the external surface. The coating layer preferably includes a polymer web, and from about 1 wppm to about 100,000 wppm of a hormone comprising a terpene dispersed throughout the polymer web. The invention also relates to methods for making hormone coating materials of the present invention. The coating compositions of the present invention preferably are implemented in human and animal food packaging materials in order to safely and efficiently protect the foodstuffs contained therein from insect infestation.Type: GrantFiled: May 16, 2007Date of Patent: July 12, 2011Inventors: Timothy Jon Leeper, Joy Michelle Thomas, Amy Marie Nichols
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Publication number: 20110059218Abstract: This disclosure pertains to a sweetener containing a high intensity sweetener and a taste modifying composition. In another aspect of the invention is a sweetener containing a high intensity sweetener, a taste modifying composition and a bulking material. Also disclosed are methods of making a sweetener of the present invention and methods of using the sweetener.Type: ApplicationFiled: May 11, 2009Publication date: March 10, 2011Applicant: CARGILL INCORPORATEDInventors: Glenn A. Corliss, Melanie J. Goulson, Brian D. Guthrie, Chin Hong Paul Kim, John Thomas McDonald, Drew Pecore, Troy Allen Rhonemus, Thomas A. Sheehan, Norris Sun, Carrie Michelle Thomas, Nese Yurttas
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Patent number: 7250396Abstract: The present invention relates to hormone coating layers having desirable hormone delivery characteristics and product lifetime. In one embodiment, the invention is a hormone composition including a substrate having an external surface, and a coating layer disposed on the external surface. The coating layer preferably includes a polymer web, a UV protectant material, and from about 1 wppm to about 100,000 wppm of a hormone dispersed throughout the polymer web. The invention also relates to methods for making hormone coating materials of the present invention. The coating compositions of the present invention preferably are implemented in human and animal food packaging materials in order to safely and efficiently protect the foodstuffs contained therein from insect infestation.Type: GrantFiled: September 10, 2003Date of Patent: July 31, 2007Assignee: Ashland Licensing and Intellectual Property LLCInventors: Timothy Jon Leeper, Joy Michelle Thomas, Amy Marie Nichols
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Patent number: 7204994Abstract: The present invention relates to hormone coating layers having desirable hormone delivery characteristics and product lifetime. In one embodiment, the invention is a hormone composition including a substrate having an external surface, and a coating layer disposed on the external surface. The coating layer preferably includes a polymer web, a UV protectant material, and from about 1 wppm to about 100,000 wppm of a hormone dispersed throughout the polymer web. The invention also relates to methods for making hormone coating materials of the present invention. The coating compositions of the present invention preferably are implemented in human and animal food packaging materials in order to safely and efficiently protect the foodstuffs contained therein from insect infestation.Type: GrantFiled: February 3, 2003Date of Patent: April 17, 2007Assignee: Ashland Licensing and Intellectual Property LLCInventors: Timothy Jon Leeper, Joy Michelle Thomas, Amy Marie Nichols
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Publication number: 20040151748Abstract: The present invention relates to hormone coating layers having desirable hormone delivery characteristics and product lifetime. In one embodiment, the invention is a hormone composition including a substrate having an external surface, and a coating layer disposed on the external surface. The coating layer preferably includes a polymer web, a UV protectant material, and from about 1 wppm to about 100,000 wppm of a hormone dispersed throughout the polymer web. The invention also relates to methods for making hormone coating materials of the present invention. The coating compositions of the present invention preferably are implemented in human and animal food packaging materials in order to safely and efficiently protect the foodstuffs contained therein from insect infestation.Type: ApplicationFiled: February 3, 2003Publication date: August 5, 2004Inventors: Timothy Jon Leeper, Joy Michelle Thomas, Amy Marie Nichols
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Patent number: 6746736Abstract: The present invention is a composition for use as an oil and grease resistant coating for packaging materials including a radiation sensitive monomer; a photopolymerization initiator; and an additive, wherein the additive preferably is a chlorinated paraffin. Preferably, the composition is used to treat the surface of a paper or paperboard substrate and the substrate preferably is used subsequently in the manufacture of packaging materials, such as pet food bags.Type: GrantFiled: March 2, 2001Date of Patent: June 8, 2004Assignee: Actinic, Inc.Inventors: Timothy Jon Leeper, Joy Michelle Thomas
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Publication number: 20020164440Abstract: The present invention is a composition for use as an oil and grease resistant coating for packaging materials including a radiation sensitive monomer; a photopolymerization initiator; and an additive, wherein the additive preferably is a chlorinated paraffin. Preferably, the composition is used to treat the surface of a paper or paperboard substrate and the substrate preferably is used subsequently in the manufacture of packaging materials, such as pet food bags.Type: ApplicationFiled: March 2, 2001Publication date: November 7, 2002Inventors: Timothy Jon Leeper, Joy Michelle Thomas
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Patent number: 4870975Abstract: A suction canister assembly includes an outer collection bottle having a bottle mouth, an inner canister nested therein having a canister mouth and having a valve device at its bottom end, a dual closure lid closing off both the bottle mouth and the canister mouth and having an inlet port and an outlet port in communication with the canister, and a fluid porous specimen receptacle suspended from the lid and surrounding the inlet port. With the valve device open, a catheter assembly is exteriorly connected to the inlet port while negative pressure is applied to the outlet port. The catheter assembly is used for vacuum aspiration of a patient with solid material being retained within the receptacle and liquid material passes into the canister, through the valve device, and into the collection bottle.Type: GrantFiled: July 5, 1988Date of Patent: October 3, 1989Inventors: Scott Cronk, Michelle Thomas
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Patent number: D777430Type: GrantFiled: May 22, 2014Date of Patent: January 31, 2017Inventor: Cheryl Michelle Thomas
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Patent number: D941066Type: GrantFiled: July 20, 2020Date of Patent: January 18, 2022Inventor: Michelle Thomas