Abstract: A battery monitoring system includes a hydrogen sensing system configured to selectively measure a plurality of hydrogen concentrations in a plurality of battery cells, respectively. A controller is configured to detect battery cell overtemperature in at least one of the plurality of battery cells in response to a corresponding one of the plurality of measured hydrogen concentrations of the plurality of battery cells.

Abstract: A battery monitoring system includes a carbon dioxide sensing system configured to selectively measure carbon dioxide concentrations within a plurality of battery cells, respectively, that are connected in parallel. A controller is configured to detect cathode overpotential in the plurality of battery cells in response to the measured carbon dioxide concentrations of the plurality of battery cells.

Abstract: An imaging device includes: a sensor to detect a first target spectrum, the first target spectrum corresponding to a thermal imaging region of an infrared (IR) spectrum; and an optical device to transmit external light to the sensor, the optical device including: a substrate; and a plurality of nanostructures on the substrate, and to collimate at least the first target spectrum in the external light on the sensor. The plurality of nanostructures are spaced apart from each other, and at least one of the plurality of nanostructures has a different geometric size from that of another.

Abstract: A system for calculating. A scratch memory is connected to a plurality of configurable processing elements by a communication fabric including a plurality of configurable nodes. The scratch memory sends out a plurality of streams of data words. Each data word is either a configuration word used to set the configuration of a node or of a processing element, or a data word carrying an operand or a result of a calculation. Each processing element performs operations according to its current configuration and returns the results to the communication fabric, which conveys them back to the scratch memory.

Abstract: The disclosure is generally related to spherical nucleic acids (SNAs), nanostructures with a core surrounded by a radial presentation of oligonucleotides, that can target multiple classes of immune cells. Methods of making and using the nanoparticles are also provided herein. In some aspects, the disclosure provides a spherical nucleic acid (SNA) comprising: (a) a nanoparticle core; (b) a shell of oligonucleotides attached to the external surface of the nanoparticle core, the shell of oligonucleotides comprising one or more immunostimulatory oligonucleotides; and (c) a first antigen that is a major histocompatibility complex type I (MHC-I) antigen, and a second antigen that is a major histocompatibility complex type II (MHC-II) antigen.

Abstract: An image sensor includes a time-resolving sensor and a processor. The time-resolving sensor outputs a first signal and a second signal pair in response detecting one or more photons that have been reflected from an object. A first ratio of a magnitude of the first signal to a sum of the magnitude of the first signal and a magnitude of the second signal is proportional to a time of flight of the one or more detected photons. A second ratio of the magnitude of the second signal to the sum of the magnitude of the first signal and the magnitude of the second signal is proportional to the time of flight of the one or more detected photons. The processor determines a surface reflectance of the object where the light pulse has been reflected based on the first signal and the second signal pair and may generate a grayscale image.

Abstract: Provided is a readout integrated circuit of a FMCW LiDAR system includes a transimpedance amplifier to receive an optical signal of optical mixer output from balanced PIN photo diode, convert the received optical signal into a current signal including a mixed signal of high and low frequencies, and convert the current signal into a voltage signal including a low frequency sinusoidal waveform, a comparator to receive the voltage signal, and generate a pulse signal from the voltage signal, a primary counter to receive a primary signal corresponding to the pulse signal, and count a number of pulses to generate primary counter data, a reference counter to receive a reference signal, and count a number of pulses to generate reference counter data, and an arithmetic logic unit to receive the primary and reference counter data, and calculate depth information corresponding to a distance of a target.

Abstract: Provided herein are antibodies, or antigen binding portions thereof, that bind to glucocorticoid-inducible TNF receptor (GITR). Also provided are uses of these proteins in therapeutic applications, such as in the treatment of cancer. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain variable region of the antibodies, and vectors comprising the polynucleotides encoding the heavy and/or light chain variable region of the antibodies.

Abstract: The present invention provides polypeptide modulators of complement activity, including cyclic polypeptide modulators. Also provided are methods of utilizing such modulators as therapeutics.

Abstract: Novel compounds, compositions, and methods of using and preparing the same, which may be useful for treating alpha-1 antitrypsin deficiency (AATD).

Abstract: A pixel cell for a CMOS image sensor includes an isolation structure that isolates a pixel transistor region from a pixel photodiode region. On a front side of the image sensor, the isolation structure includes a first shallow trench isolation (STI) structure, a second STI structure and a semiconductor region between the first STI structure and the second STI structure, and an implant region formed from a p-type semiconductor that is in contact with the semiconductor region and extends toward a backside of the image sensor. The semiconductor region is formed from the first type semiconductor. On a backside of the image sensor, the isolation structure includes a trench isolation structure extending from the backside toward the front side and that contacts the implant region.

Abstract: Described herein are compounds of Formula I, wherein the variables are defined herein, their use as HSD17B13 inhibitors and/or degraders, pharmaceutical compositions containing such compounds and their use to treat, for example, NAFLD and NASH.

Abstract: A flavor or aroma charcoal material, such as charcoal briquets, which is formulated to include a flavor or aroma component. The charcoal material may include a smoldering agent (e.g., limestone), wood particles (e.g., sawdust), a binder, and the flavor or aroma component (herbs and/or spices). The flavor or aroma charcoal material may not be configured as a fuel charcoal material, for example, it may be substantially void of char and/or coal. In an embodiment, the flavor or aroma charcoal material may be provided as part of a blend of different charcoal materials that includes both flavor or aroma briquets in combination with fuel briquets (e.g., which fuel briquets include char and/or coal, while the flavor briquets do not). The flavor briquets provide enhanced aroma and/or flavor to the grilling experience.

Abstract: The present invention provides modulators of complement activity. Also provided are methods of utilizing such modulators as therapeutics.

Abstract: A pixel for an image sensor is disclosed that includes a photodiode, a thin-film layer and a reflective layer. The photodiode includes a first side and a second side that is opposite the first side, and receives incident light on the first side. The thin-film layer is formed on the first side of the photodiode and provides a unidirectional phase-shift to light passing from the photodiode to the thin-film layer. The thin-film layer has a refractive index that less than a refractive index of material forming the photodiode. The unidirectional phase-shift may be a unidirectional it phase shift at a target near-infrared light wavelength. The reflective layer is formed on the second side of the photodiode and reflects light passing from the photodiode to the reflective layer toward the first side of the photodiode. The reflective layer may be a thin-film layer, a Distributed Bragg Reflector layer, or a metal.

Abstract: A pixel for an image sensor includes a photon sensor, a memory, and an accumulator. The photon sensor element portion outputs a signal to an accumulator, which then may add value stored in memory together and may transfer the result to the memory of another pixel. The pixel may be analog or digital and may be used in a pixel array for compressed sensing imaging. During imaging, a pseudo-random mask may also be used. The data collected during imaging may be used in compressed sensing and may be sent to an offline storage to be processed.

Abstract: An image sensor includes a time-resolving sensor and a processor. The time-resolving sensor outputs a first signal and a second signal pair in response detecting one or more photons that have been reflected from an object. A first ratio of a magnitude of the first signal to a sum of the magnitude of the first signal and a magnitude of the second signal is proportional to a time of flight of the one or more detected photons. A second ratio of the magnitude of the second signal to the sum of the magnitude of the first signal and the magnitude of the second signal is proportional to the time of flight of the one or more detected photons. The processor determines a surface reflectance of the object where the light pulse has been reflected based on the first signal and the second signal pair and may generate a grayscale image.

Abstract: A package comprising an integrated device and a substrate coupled to the integrated device. The substrate comprises at least one dielectric layer and a plurality of interconnects. The plurality of interconnects include a plurality of post interconnects. The plurality of post interconnects include a post interconnect comprising a profile cross section that includes a trapezoid shape.

Abstract: Two-dimensional (2D) color information and 3D-depth information are concurrently obtained from a 2D pixel array. The 2D pixel array is arranged in a first group of a plurality of rows. A second group of rows of the array are operable to generate 2D-color information and pixels of a third group of the array are operable to generate 3D-depth information. The first group of rows comprises a first number of rows, the second group of rows comprises a second number of rows that is equal to or less than the first number of rows, and the third group of rows comprises a third number of rows that is equal to or less than the second number of rows. In an alternating manner, 2D-color information is received from a row selected from the second group of rows and 3D-depth information is received from a row selected from the third group of rows.

Abstract: A computing device includes a system that authenticates a user of the computing device. A first sensor obtains a first representation of a physical characteristic of the user that is compared to a registered representation of the physical characteristic of the user. A first level of access to the computing device is enabled based on the first representation of the physical characteristic matching the second representation of the physical characteristic. A second sensor obtains a first representation of a liveness characteristic of the user that indicates that the user is alive. The first representation of the liveness characteristic is compared to a registered representation of the liveness characteristic of the user. A second level of access to the computing device is enabled based on the first representation of the liveness characteristic of the user matching the second representation of the liveness characteristic of the user.