Patents by Inventor Michihiro Sugano

Michihiro Sugano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for increasing brown fat, comprising administering conjugated linoleic acid as active ingredient
    Patent number: 6451336
    Abstract: There is provided an agent for increasing brown fat, comprising a conjugated linoleic acid as an active ingredient.
    Type: Grant
    Filed: April 28, 2000
    Date of Patent: September 17, 2002
    Assignee: Rinoru Oil Mills Co., Ltd.
    Inventors: Michihiro Sugano, Masanobu Sakono, Kazunori Koba, Hitoshi Okuyama, Masaaki Kasai, Toshio Iwata
  • Body fat-reducing agent comprising dioxabicyclo[3.3.0] octane derivative as active ingredient
    Patent number: 6358998
    Abstract: There is provided an agent for reducing body fat, comprising as an active ingredient a dioxabicyclo[3.3.0]octane derivative represented by formula (I): wherein R1 to R6 each independently represent a hydrogen atom or an alkyl group having 1 to 3 carbon atoms, provided that R1 and R2 and/or R4 and R5 combine together to form a methylene or ethylene group; and n, m, and l are each 0 or 1.
    Type: Grant
    Filed: April 28, 2000
    Date of Patent: March 19, 2002
    Assignee: Rinoru Oil Mills Co., LTD
    Inventors: Michihiro Sugano, Masanobu Sakono, Kazunori Koba, Hitoshi Okuyama, Masaaki Kasai, Toshio Iwata
  • Agent for increasing brown fat, comprising conjugated linoleic acid as active ingredient
    Publication number: 20020015771
    Abstract: There is provided an agent for increasing brown fat, comprising a conjugated linoleic acid as an active ingredient.
    Type: Application
    Filed: April 28, 2000
    Publication date: February 7, 2002
    Inventors: Michihiro Sugano, Masanobu Sakuno, Kazunori Koba, Hitoshi Okuyama, Masaaki Kasai, Toshio Iwata
  • Agent for prevention or alleviation of allergy symptoms
    Patent number: 5922760
    Abstract: An agent for the prevention or alleviation of allergy symptoms contains as an effective component a dioxabycyclo?3.3.0!octane derivative represented by the following general formula (I): ##STR1## where R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 each independently represent a hydrogen atom or alkyl group of 1-3 carbon atoms, or R.sup.1 and R.sup.2 and/or R.sup.4 and R.sup.5 together represent a methylene or ethylene group, and n, m and l represent 0 or 1.An agent for the prevention or alleviation of allergy symptoms also contains as an effective component an antioxidant in addition to the dioxabicyclo?3.3.0!octane derivative.
    Type: Grant
    Filed: June 19, 1997
    Date of Patent: July 13, 1999
    Assignee: Suntory Limited
    Inventors: Kengo Akimoto, Michihiro Sugano, Koji Yamada, Michiko Nonaka, Jiong-Yan Gu
  • Composition containing dioxabicyclo [3.3.0] octane derivative
    Patent number: 5637610
    Abstract: A food, drink, pharmaceutical, cosmetic composition or food additive comprising a dioxabicyclo[3.3.0]octane derivative represented by the following general formula (I): ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 independently represent a hydrogen atom or an alkyl group having 1 to 3 carbon atoms, or R.sup.1 and R.sup.2 and/or R.sup.4 and R.sup.5 together form a methylene group or an ethylene group, and n, m and l are 0 or 1; and antioxidant.
    Type: Grant
    Filed: June 20, 1994
    Date of Patent: June 10, 1997
    Assignee: Suntory Limited
    Inventors: Ayako Nakabayashi, Yoshinori Kitagawa, Kengo Akimoto, Michihiro Sugano
  • Inhibitor for delta 5-desaturase
    Patent number: 5336496
    Abstract: A composition for inhibiting .DELTA..sup.5 -desaturase comprising an effective ingredient selected from the group consisting of lignan compounds, curcumin and piperonyl butoxide. As the lignan compounds sesamin, sesaminol, episesamin, episesaminol, sesamolin, 2-(3,4-methylenedioxyphenyl)-6-(3-methoxy-4 -hydroxyphenyl)-3,7-dioxabicyclo[3.3.0]octane, 2,6-bis-(3-methoxy-4-hydroxyphenyl)-3,7-dioxabicyclo[3.3.0]octane, and 2-(3,4-methylenedioxyphenyl)-6 -(3-methoxy-4-hydroxyphenoxy)-3,7-dioxabicyclo[3.3.0]-octane are used. Moreover the effective ingredient may be a sesame oil extract or sesame seed extract.
    Type: Grant
    Filed: April 14, 1992
    Date of Patent: August 9, 1994
    Assignee: Suntory Limited
    Inventors: Kengo Akimoto, Yoshifumi Shinmen, Hideaki Yamada, Sakayu Shimizu, Michihiro Sugano
  • Platelet activating factor antagonists, named "the phomactins", their preparation and use
    Patent number: 5308867
    Abstract: A series of new compounds, called "the phomactins" is provided and may be isolated from the culture broth of fungi of the genus Phoma. especially Phomas sp. SANK 11486 (No. FERM BP-2598). These compounds are platelet activating factor antagonists and may be used for the treatment of disorders for which known such agents may also be used.
    Type: Grant
    Filed: August 10, 1992
    Date of Patent: May 3, 1994
    Assignee: Sankyo Company, Limited
    Inventors: Aiya Sato, Michihiro Sugano, Kouhei Furuya, Takeshi Oshima, Harumitsu Kuwano, Tadashi Hata, Hideyuki Haruyama
  • Method of inhibiting metabolism of cholesterol
    Patent number: 5270335
    Abstract: A method of inhibiting the metabolism of cholesterol, comprising administering to a subject a pharmaceutical composition comprising a dioxabicyclo[3.3.0]octane derivative represented by the following general formula (I): ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 independently represent a hydrogen atom or an alkyl group having 1 to 3 carbon atoms, or R.sup.1 and R.sup.2 and/or R.sup.4 and R.sup.5 together form a methylene group or an ethylene group, and n, m and l are 0 or 1.
    Type: Grant
    Filed: October 21, 1991
    Date of Patent: December 14, 1993
    Assignee: Suntory Limited
    Inventors: Kengo Akimoto, Sumio Asami, Michihiro Sugano, Nobuaki Hirose
  • Liver function improver
    Patent number: 5211953
    Abstract: A liver function improver, food, or drink comprising, as an effective ingredient, a dioxabicyclo[3.3.0]octane derivative, such as sesamin, sesaminol espisesamin, episesaminol, sesamolin, 2-(3,4-methylenedioxyphenyl)-6-(3-methoxy-4-hydroxyphenyl)-3,7-dioxabicycl o[3.3.0]octane, 2,6-bis-(3-methoxy-4-hydroxyphenyl)-3,7-dioxabicyclo[3.3.0]octane or 2-(3,4-methylenedioxyphenyl)-6-(3-methoxy-4-hydroxyphenoxy)-3,7-dioxabicyc lo[3.3.0]octane.
    Type: Grant
    Filed: June 23, 1992
    Date of Patent: May 18, 1993
    Assignee: Suntory, Limited
    Inventors: Yoshifumi Shinmen, Kengo Akimoto, Sumio Asami, Yoshihide Suwa, Yoshinori Kitagawa, Michihiro Sugano, Hideaki Yamada, Sakayu Shimizu
  • Liver function improver
    Patent number: 5180588
    Abstract: A liver function improver, food, or drink comprising, as an effective ingredient, a dioxabicyclo[3.3.0]octane derivative, such as sesamin, sesaminol episesamin, episesaminol, sesamolin, 2-(3,4-methylene dioxyphenyl)-6-(3-methoxy-4-hydroxyphenyl)-3,7-dioxabicyclo[3.3.0]octane, 2,6-bis-(3-methoxy-4-hydroxyphenyl)-3,7-dioxabicyclo[3.3.0]octane or 2- (3,4-methylenedioxyphenyl)-6-(3-methoxy-4-hydroxyphenoxy)-3,7-dioxabicyclo [3.3.0]octane.
    Type: Grant
    Filed: July 20, 1990
    Date of Patent: January 19, 1993
    Assignee: Suntory Limited
    Inventors: Yoshifumi Shinmen, Kengo Akimoto, Sumio Asami, Yoshihide Suwa, Yoshinori Kitagawa, Michihiro Sugano, Hideaki Yamada, Sakayu Shimizu
  • Platelet activating factor antagonists, named "the phomactins" their preparation and use
    Patent number: 5151529
    Abstract: A series of new compounds, called "the phomactins" is provided and may be isolated from the culture broth of fungi of the genus Phoma, especially Phoma sp. SANK 11486 (No. FERM BP-2598). These compounds are platelet activating factor antagonists and may be used for the treatment of disorders for which known such agents may also be used.
    Type: Grant
    Filed: October 10, 1990
    Date of Patent: September 29, 1992
    Assignee: Sankyo Company, Limited
    Inventors: Aiya Sato, Michihiro Sugano, Kouhei Furuya, Takeshi Oshima, Harumitsu Kuwano, Tadashi Hata, Hideyuki Haruyama