Abstract: A temperature measurement device includes a first probe that measures a physical quantity related to a temperature of a substance on the basis of a first reference, a second probe that measures a physical quantity related to a temperature of the substance on the basis of a second reference different from the first reference, and a heat conductive member that covers the first probe and the second probe and transports heat from the substance.

Abstract: A measuring unit (103) chronologically measures a heart rate or pulse rate of a measurement subject. A computing unit (104) obtains a statistic of measuring results measured by the measuring unit (103). The computing unit (104) obtains a statistic of a plurality of measuring results measured during a set period of time by the measuring unit (103) and stored in a storage unit. A correction unit (105) corrects a photoacoustic signal detected by a detection unit (102) based on the statistic obtained by the computing unit (104). The correction unit (105) corrects the photoacoustic signal that is detected by the detection unit (102) immediately after the latest value of the heart rate or pulse rate used in the calculation of the statistic by the computing unit (104) is measured.

Abstract: A first holding member and a second holding member are arranged so as to sandwich a measurement site of a measurement subject, and are capable of clamping the measurement site. A light beam emitted from a light emitting unit is guided to the first holding member by an optical fiber, passes through an optical system, is reflected by a reflection unit, and is then incident on the measurement site. A detection unit housed in the second holding member detects a photoacoustic signal generated in the measurement site irradiated with the light beam emitted from the light emitting unit. A matching member is arranged between the second holding member and the measurement site, and is in contact with the measurement site.

Abstract: A pressurizing unit applies pressure around a measurement site of a measurement subject so as to suppress blood flow at the measurement site during a set pressurizing time. While the pressurizing unit is applying pressure around the measurement site, a detection unit detects a photoacoustic signal generated at the measurement site irradiated with a light beam. The detection unit detects a photoacoustic signal when a preset time has elapsed after the pressurizing unit started to apply pressure around the measurement site.

Abstract: Particles of a sustained-release gel which is converted into a sol by reacting with a product produced by a reaction of biomolecules with an enzyme, are disposed on a measurement unit, and a measurement target biomolecule is brought into contact with the particles. Due to this contact, a product is produced according to a reaction of the biomolecule with the enzyme contained in the particles. According to the reaction with the produced product, the sustained-release is converted into a sol, and a plurality of contained detection molecules are released to the outside of the particles.

Abstract: A light emitting unit irradiates a measurement site of a measurement subject with a light beam having a wavelength that is absorbed by a measurement target substance. A detection unit detects a photoacoustic signal generated in the measurement site irradiated with the light beam emitted from the light emitting unit. A resonator is arranged so as to clamp the measurement site, and causes the above-described photoacoustic signal to resonate. The resonator is constituted by a first reflection unit and a second reflection unit. The first reflection unit is arranged between the light irradiation unit and the measurement site. Also, the light beam passes through the first reflection unit. The second reflection unit is arranged between the detection unit and the measurement site.

Abstract: A measurement unit is attached to a measurement subject and measures acceleration in time series. A body movement calculation unit obtains the magnitude of body movement indicating the magnitude of a motion of the measurement subject based on acceleration measured by the measurement unit. A singular point extraction unit extracts, as a singular point, a time point at which the magnitude of body movement obtained by the body movement calculation unit exceeds a threshold value. A matching unit rectifies a change in a photoacoustic signal between before and after the singular point extracted by the singular point extraction unit.

Abstract: A component concentration measurement device includes a light application unit (101) that applies pulsed beam light (121) of a wavelength that is absorbed by glucose to a site of measurement (151), and a detection unit (102) that detects a photoacoustic signal which is generated at the site of measurement (151) where the beam light (121) emitted from the light application unit (101) has been applied. The component concentration measurement device also includes a moisture measurement unit (103) that measures an amount of moisture in skin at the site of measurement (151), and a correction unit (104) that corrects an acoustic signal detected by the detection unit (102) with the amount of moisture measured by the moisture measurement unit (103).

Abstract: A component concentration measurement device includes a light application unit that applies beam light of a wavelength that is absorbed by glucose to a site of measurement, and a detection unit that detects a photoacoustic signal which is generated at the site of measurement where the beam light emitted from the light application unit has been applied. The component concentration measurement device also includes a thickness measurement unit that measures a thickness of the site of measurement, and a correction unit that corrects an acoustic signal detected by the detection unit with the thickness measured by the thickness measurement unit.

Abstract: A light source unit emits beam light of a wavelength that is absorbed by glucose. A light application control unit gives multiple-application of the beam light emitted by the light source unit to a site of measurement. A detection unit detects each of a plurality of photoacoustic signals that are generated at the site of measurement due to the multiple-application of the beam light by the light application control unit. A processing unit averages the plurality of photoacoustic signals detected by the detection unit.

Abstract: An in-vivo temperature measurement device includes a plurality of thermal resistors, temperature sensors for measuring an epidermis temperature of a living body, and temperature sensors for measuring an upper surface temperature that are provided at both ends of the thermal resistors, respectively, a memory that stores an estimation model of the core temperature of the living body that takes into consideration a non-thermal equilibrium state of the living body, and thermal resistance values of the thermal resistors, and an arithmetic circuit that estimates, based on the plurality of temperatures measured by the temperature sensors and the temperature sensors, the core temperature of the living body using the estimation model and the thermal resistance values, and the thermal resistance values are different from one another.

Abstract: A device includes: an ultrasonic wave irradiation unit that irradiates a living body with an ultrasonic wave; an ultrasonic wave detection unit that receives an ultrasonic wave reflected by the living body; and a calculation unit that calculates an amount of temperature change in the living body. The calculation unit is configured to: calculate a frequency of an ultrasonic wave amplified in the living body, based on information on a structure of the living body; perform frequency analysis on the ultrasonic wave received by the ultrasonic wave detection unit and acquire an amplitude spectrum of the ultrasonic wave; identify, from the amplitude spectrum, a peak frequency closest to the frequency of the ultrasonic wave; calculate an amount of frequency change, from two peak frequencies identified by ultrasonic wave irradiations in twice; and calculate an amount of temperature change in the living body from the amount of frequency change.

Abstract: A component concentration measuring apparatus includes: a dielectric spectroscopy portion that irradiates a measurement subject with electromagnetic waves and measures a complex permittivity, thereby acquiring a dielectric spectroscopy spectrum; a temperature measurement portion that measures a temperature of the measurement subject; a signal processing portion that corrects the dielectric spectroscopy spectrum according to the temperature measured by the temperature measurement portion; and a calculating portion that applies a calibration model generated in advance from a dielectric spectroscopy spectrum of a sample whose component concentration is known, to the dielectric spectroscopy spectrum corrected by the signal processing portion, thereby calculating a component concentration of the measurement subject.

Abstract: A component concentration measurement device includes a light application unit that applies pulsed beam light of a wavelength that is absorbed by a target substance for measurement to a site of measurement, and a detection unit that detects a photoacoustic signal generated in the site of measurement where the beam light emitted from the light application unit has been applied. The light application unit applies the pulsed beam light with a pulse width at which a photoacoustic wave that occurs at a rising edge of a light pulse and a photoacoustic wave that occurs at a falling edge of the light pulse do not interfere with each other.

Abstract: An internal body temperature measurement device includes: a temperature sensor which measures an epidermis temperature of a living body; a heat flux sensor which measures a magnitude of a heat flux discharged from a body surface of the living body; a blood flow sensor which measures a blood flow rate in a vicinity of the heat flux sensor; and a storage unit which stores a relation between the blood flow rate in the vicinity of the heat flux sensor and a core temperature depth. A correction amount of the core temperature depth corresponding to the blood flow rate in the vicinity of the heat flux sensor is obtained on a basis of the relation stored in the storage unit, and a core temperature of the living body is calculated from the epidermis temperature, the magnitude of the heat flux, and the correction amount of the core temperature depth.

Abstract: A component concentration measuring apparatus includes: a dielectric spectroscopy portion that irradiates a measurement subject with electromagnetic waves, thereby acquiring a complex permittivity spectrum; a signal processing portion that standardizes an imaginary part or an imaginary part spectrum of a complex permittivity at a frequency other than a frequency of an isosbestic point of the measurement subject, using an imaginary part of a complex permittivity at the frequency of the isosbestic point, out of the complex permittivity spectrum; and a calculating portion that applies a calibration model generated in advance from an imaginary part or an imaginary part spectrum of a complex permittivity of a sample whose component concentration is known, to the imaginary part or the imaginary part spectrum of the complex permittivity standardized by the signal processing portion, thereby calculating a component concentration of the measurement subject.

Abstract: A light irradiation unit configured to irradiate a measurement part with a light beam that has a wavelength absorbed by glucose and a detection unit configured to detect a photoacoustic signal generated from the measurement part irradiated with the light beam emitted from the light irradiation unit are included. The light irradiation unit irradiates the measurement part by scanning the light beam 2-dimensionally. The measurement part is irradiated with the light beam through raster scanning. For example, the light beam has a beam diameter of about 100 ?m and is scanned at a scanning speed of about 100 ?m/10 ms.

Abstract: A heat flux sensor including two temperature sensors is used to obtain time-series data of a core temperature of a living body, and a blood flow rate in a vicinity of the heat flux sensor is measured by a blood flow sensor. In an arithmetic circuit, a delay time until a fluctuation of the core temperature of the living body is reflected on an epidermis temperature is calculated on the basis of the blood flow rate measured by the blood flow sensor and a previously prepared relation between the blood flow rate and the delay time until the fluctuation of the core temperature of the living body is reflected on the epidermis temperature, and a time corresponding to the core temperature of the living body on the basis of the delay time is corrected.

Abstract: In a biological signal measurement system of this invention, biological digital data is generated from a biological signal measured by a biological signal measurement apparatus, and first feature amount data extracted from the biological digital data and downsized biological digital data are transmitted to a portable terminal. In a biological information measurement apparatus of this invention, biological feature amount data is extracted from measured biological waveform data, and at least one of the biological waveform data and the biological feature amount data is transmitted to an external device. It is possible to provide a biological signal measurement system capable of continuously measuring a biological signal for a long time without disturbing daily life and provide a biological information measurement apparatus capable of implementing downsizing and long life of a battery.

Abstract: A suction channel is made of a flexible resin, and is formed in a base. The suction channel suctions sweat that has come into contact with the detection electrode. The suction channel makes use of surface tension from micro channels to suction liquid into an interior from a suction port. A sodium ion detection electrode, a potassium ion detection electrode, and a reference electrode, which are detection electrodes for detecting ions contained in the sweat, are formed on an inner wall of a channel of the suction channel.