Patents by Inventor Michinori Koyama

Michinori Koyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Remedy for autoimmune diseases
    Patent number: 6458848
    Abstract: Disclosed is use of nonsteroidal anti-estrogen compounds such as toremifene citrate as active ingredient for treating autoimmune diseases.
    Type: Grant
    Filed: January 10, 2002
    Date of Patent: October 1, 2002
    Assignees: Nippon Kayaku Kabushiki Kaisha, Orion-yhtyma Oy
    Inventors: Junpei Itoh, Osamu Miyazaki, Hisao Ekimoto, Michinori Koyama, Tetsushi Saino, Lauri Kangas, Anni Warri, Christer Granberg
  • Remedy for autoimmune diseases
    Publication number: 20020107231
    Abstract: Disclosed is use of nonsteroidal anti-estrogen compounds such as toremifene citrate as active ingredient for treating autoimmune diseases.
    Type: Application
    Filed: January 10, 2002
    Publication date: August 8, 2002
    Inventors: Junpei Itoh, Osamu Miyazaki, Hisao Ekimoto, Michinori Koyama, Tetsushi Saino, Lauri Kangas, Anni Warri, Christer Granberg
  • Remedy for autoimmune diseases
    Patent number: 6387958
    Abstract: Disclosed is use of nonsteroidal anti-estrogen compounds such as toremifene citrate as active ingredient for treating autoimmune diseases.
    Type: Grant
    Filed: July 16, 2001
    Date of Patent: May 14, 2002
    Assignees: Nippon Kayaku Kabushiki Kaisha, Orion-yhtyma Oy
    Inventors: Junpei Itöh, Osamu Miyazaki, Hisao Ekimoto, Michinori Koyama, Tetsushi Saino, Lauri Kangas, Anni Warri, Christer Granberg
  • Remedy for autoimmune diseases
    Patent number: 6355688
    Abstract: Disclosed is use of nonsteroidal anti-estrogen compounds such as toremifene citrate as active ingredient for treating autoimmune diseases.
    Type: Grant
    Filed: March 1, 2000
    Date of Patent: March 12, 2002
    Inventors: Junpei Itoh, Osamu Miyazaki, Hisao Ekimoto, Michinori Koyama, Tetsushi Saino, Lauri Kangas, Anni Warri, Christer Granberg
  • Remedy for autoimmune diseases
    Patent number: 6184253
    Abstract: Disclosed is use of nonsteroidal anti-estrogen compounds such as toremifene citrate as active ingredient for treating autoimmune diseases.
    Type: Grant
    Filed: November 16, 1998
    Date of Patent: February 6, 2001
    Assignees: Nippon Kayaku Kabushiki Kaisha, Orion-yhtyma Oy
    Inventors: Junpei Itoh, Osamu Miyazaki, Hisao Ekimoto, Michinori Koyama, Tetsushi Saino, Lauri Kangas, Anni Warri, Christer Granberg
  • Remedy for autoimmune diseases
    Patent number: 5886049
    Abstract: Disclosed is use of nonsteroidal anti-estrogen compounds such as toremifene citrate as active ingredient for treating autoimmune diseases.
    Type: Grant
    Filed: April 22, 1997
    Date of Patent: March 23, 1999
    Assignees: Nippon Kayaku Kabushiki Kaisha, Orion-yhtyma Oy
    Inventors: Junpei Itoh, Osamu Miyazaki, Hisao Ekimoto, Michinori Koyama, Tetsushi Saino, Lauri Kangas, Anni Warri, Christer Granberg
  • Peptides and acid addition salts thereof
    Patent number: 4185156
    Abstract: The compounds of this invention represented by the following formula: ##STR1## (wherein R is hydrogen atom, an alkyl group having C.sub.1 to C.sub.4, a hydroxy group or a halogen atom) can be obtained by condensing the compounds represented by the following formula: ##STR2## wherein R is as defined above, X is hydrogen atom, and Y is hydrogen atom or an amino protecting group or reactive derivatives thereof with (S)-arginine according to a method commonly employed in the peptide chemistry.The peptides according to this invention have strong inhibitory activity against aminopeptidase B, can raise immunity of the organisms and prove useful for inhibiting transfer of cancer and relapse thereof. Also, when used jointly with Bleomycin which is an antitumor agent, they can greatly enhance the antitumor effect of said agent.
    Type: Grant
    Filed: September 15, 1978
    Date of Patent: January 22, 1980
    Assignee: Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai
    Inventors: Hamao Umezawa, Takaaki Aoyagi, Tomio Takeuchi, Tetsushi Saino, Michinori Koyama