Abstract: An immunochromatography carried out by illuminating a fluorescent substance in a membrane with excitation light and detecting fluorescence emitted from the fluorescent substance, the immunochromatography comprising the steps of: preparing a membrane having a transparent film, the transparent film being closely attached to the surface of the membrane, the transparent film satisfying a specific property related to a refractive index with respect to analyte liquid; illuminating a fluorescent substance in the membrane with excitation light through the transparent film; and detecting another fluorescence components not exceeding the critical angle, the another fluorescence components being included in the fluorescence emitted from the fluorescent substance, the detection being made by virtue of the fluorescence components passing through the film.

Abstract: A system of quantitatively determining a biomolecule, which has: allowing fluorescent silica particles capable of emitting fluorescence detectable by a flow cytometer to capture a target biomolecule fluorescent-labelled for quantitative determination; detecting the fluorescence emitted from the fluorescent silica particles themselves by using the flow cytometer; and measuring the intensity of the fluorescence of the labelled target biomolecule, thereby quantitatively determining the target biomolecule.

Abstract: A particulate mixture etc., which can be used as a precursor of lithium transition metal silicate-type compound of small particle size and low crystallinity, is provided. Further, a cathode active material that can undergo charge-and-discharge reaction in room temperature, and comprises lithium transition metal silicate-type compound, is provided. It is a mixture of silicon oxide particulates, transition metal oxide particulates, and lithium transition metal silicate particulates, and its powder X-ray diffraction measurement shows diffraction peaks near 2?=33.1° and near 2?=35.7°, and said silicon oxide particulates and said transition metal oxide particulates are amorphous, and said lithium transition metal silicate particulates are in a microcrystalline or amorphous state. Furthermore, a cathode active material obtained by grinding the active material aggregate obtained by heat-treating this particulate mixture is provided.

Abstract: A particulate mixture which can be used as a precursor of lithium transition metal silicate-type compound of small particle size and low crystallinity, is provided. It is a mixture of silicon oxide particulates, transition metal oxide particulates, and lithium transition metal silicate particulates, and its powder X-ray diffraction measurement shows diffraction peaks near 2?=33.1° and near 2?=35.7°, and said silicon oxide particulates and said transition metal oxide particulates are amorphous, and said lithium transition metal silicate particulates are in a microcrystalline or amorphous state.

Abstract: A method of producing functional molecule-containing silica nanoparticles on which a biomolecule is bonded, containing the steps of: allowing silica nanoparticles containing a functional molecule and having a thiol group on a surface thereof to coexist with a linker molecule having a maleimido group and a carboxyl group in an aprotic solvent, thereby allowing formation of a thioether bond between the thiol group and the maleimido group, and obtaining functional molecule-containing silica nanoparticles on which the linker molecule is bonded; and allowing the functional molecule-containing silica nanoparticles on which the linker molecule is bonded to coexist with carbodiimide and a biomolecule having an amino group in an aqueous solvent, thereby allowing formation of an amide bond between the carboxyl group active esterified by the carbodiimide, and the amino group of the biomolecule.

Abstract: The object of the present invention is to provide a lithium transition metal silicate-type cathode active material that shows superior cycle characteristics, and shows little deterioration of discharge capacity even after repeated charge-and-discharge. In the present invention, a cathode active material that is expressed by the general formula Li2-yFe1-xMxSi1-yXyO4 (M=at least one transition metal selected from the group consisting of Mn, Ti, Cr, V, Ni, Co, Cu, Zn, Al, Ge, Zr, Mo, W; X=at least one element selected from the group consisting of Ti, Cr, V, Zr, Mo, W, P, B; 0?x<1, 0?y<0.25), and contains a lithium transition metal silicate, which comprises a mixed phase of an orthorhombic-type structure with a space group Pmn21 symmetry, and a monoclinic-type structure with a space group P21/n symmetry, is provided.

Abstract: The object of the present invention is to provide a method for producing lithium transition metal phosphate with a small particle size and uniform element spatial distribution, which enables continuous and large-scale synthesis. Its solution is as follows: A particulate mixture is synthesized by the spray-combustion method, wherein a mixed solution containing a lithium source, a transition metal source, and a phosphorus source is supplied into a flame along with a combustion-supporting gas and a flammable gas, as a mist-like droplet. It is a method for producing lithium transition metal phosphate-type cathode active material, which further comprises a process of mixing the synthesized particulate mixture with a carbon source, a process of calcining the particulate mixture under inert gas atmosphere to produce an active material aggregate, and a process of pulverizing the active material aggregate.

Abstract: An object of the present invention is to provide a cathode active material which contains small-particle sized and low-crystalline lithium transition metal silicate and which undergoes charge-discharge reaction at room temperature. The cathode active material for a non-aqueous electrolyte secondary battery is characterized by containing a lithium transition metal silicate and exhibits diffraction peaks having half widths of 0.175 to 0.6°, the peaks observed through powder X-ray diffractometry within a 2? range of 5 to 50°.

Abstract: A particulate mixture etc., which can be used as a precursor of lithium transition metal silicate-type compound of small particle size and low crystallinity, is provided. Further, a cathode active material that can undergo charge-and-discharge reaction in room temperature, and comprises lithium transition metal silicate-type compound, is provided. It is a mixture of silicon oxide particulates, transition metal oxide particulates, and lithium transition metal silicate particulates, and its powder X-ray diffraction measurement shows diffraction peaks near 2?=33.1° and near 2?=35.7°, and said silicon oxide particulates and said transition metal oxide particulates are amorphous, and said lithium transition metal silicate particulates are in a microcrystalline or amorphous state. Furthermore, a cathode active material obtained by grinding the active material aggregate obtained by heat-treating this particulate mixture is provided.

Abstract: Labelled silica nanoparticles for immunochromatographic reagent, comprising silica nanoparticles containing a labelled substance.

Abstract: Labelled silica nanoparticles for immunochromatographic reagent, comprising silica nanoparticles containing a labelled substance.

Abstract: A colloidal silica particle containing a light-absorbing substance, comprising a colloidal silica particle and a light-absorbing substance distributed over the colloidal silica particle, wherein the light-absorbing substance is chemically bound to or adsorbed on a silica component.

Abstract: A fluorescent labeling reagent of the present invention includes an inorganic fluorescent particle and a material (A) having a material (B) of biological origin adsorbed or bound thereto. The inorganic fluorescent particle is integrated with the material (A) so as to form the reagent of the present invention. The inorganic fluorescent particle used in the present invention is capable of emitting light with a wavelength of 650 nm to 1600 nm in the infrared region or the near-infrared region which can be detected by means of Si—CCD or InGaAs—PD and can penetrate an H2O rich sample when excited by light with a wavelength of 650 nm or longer which has the shortest transparent wavelength of AlInGaP-LD including oxygen adsorption type hemoglobin used for DVDs etc.

Abstract: A wavelength conversion module according to the present invention includes an external resonator, a semiconductor laser module and a wavelength conversion device for converting a wavelength of light output from the semiconductor laser module into a shorter wavelength. This wavelength conversion device includes at least one of a nonlinear crystal for generating SFG (Sum-frequency Generation) light and a nonlinear crystal for generating SHG (Second Harmonic Generation) light. Each of the SFG generating element and the SHG generating element of the wavelength conversion device may have a periodically-poled ridge-waveguide structure or a periodically-poled proton-exchanged-waveguide structure.

Abstract: A colloidal silica particle containing a light-absorbing substance, comprising a colloidal silica particle and a light-absorbing substance distributed over the colloidal silica particle, wherein the light-absorbing substance is chemically bound to or adsorbed on a silica component.

Abstract: A system of quantitatively determining a biomolecule, which has: allowing fluorescent silica particles capable of emitting fluorescence detectable by a flow cytometer to capture a target biomolecule fluorescent-labelled for quantitative determination; detecting the fluorescence emitted from the fluorescent silica particles themselves by using the flow cytometer; and measuring the intensity of the fluorescence of the labelled target biomolecule, thereby quantitatively determining the target biomolecule.

Abstract: Labelled silica nanoparticles for immunochromatographic reagent, comprising silica nanoparticles containing a labelled substance.

Abstract: Colloidal silica particles containing a fluorescent dye compound, composed of a silica particle containing a silica component and a fluorescent dye compound chemically bound or adsorbed thereto, wherein the colloidal silica particles containing a fluorescent dye compound have an average diameter of 30 nm or less, and wherein said silica particles are used simultaneously as fluorescent-labelling nanobeads; a fluorescent nano-material comprising said colloidal silica particles; and a biochip and an assay method using the same.

Abstract: A fluorescent labeling reagent of the present invention includes an inorganic fluorescent particle and a material (A) having a material (B) of biological origin adsorbed or bound thereto. The inorganic fluorescent particle is integrated with the material (A) so as to form the reagent of the present invention. The inorganic fluorescent particle used in the present invention is capable of emitting light with a wavelength of 650 nm to 1600 nm in the infrared region or the near-infrared region which can be detected by means of Si-CCD or InGaAs-PD and can penetrate an H2O rich sample when excited by light with a wavelength of 650 nm or longer which has the shortest transparent wavelength of AlInGaP-LD including oxygen adsorption type hemoglobin used for DVDs etc.

Abstract: A wavelength conversion module according to the present invention includes an external resonator, a semiconductor laser module and a wavelength conversion device for converting a wavelength of light output from the semiconductor laser module into a shorter wavelength. This wavelength conversion device includes at least one of a nonlinear crystal for generating SFG (Sum-frequency Generation) light and a nonlinear crystal for generating SHG (Second Harmonic Generation) light. Each of the SFG generating element and the SHG generating element of the wavelength conversion device may have a periodically-poled ridge-waveguide structure or a periodically-poled proton-exchanged-waveguide structure.