Abstract: A heating and hot-water-supply apparatus is provided with: a control unit that performs control on the basis of detection parameters of a plurality of detection means installed at the aforementioned locations and a setting parameter set in an operation unit. The distribution means can adjust the distribution ratio so as to correspond to a heating operation, a hot-water supply operation, and the simultaneous heating and hot-water-supply operation. The control unit prohibits the simultaneous heating and hot-water-supply operation in a case in which the required heating capacity for the hot-water supply operation calculated on the basis of the detection parameters and the setting parameter is equal to or greater than a predetermined standard capacity.

Abstract: When a hot water supply operation is started, a single mode is used in which hot water is output only from a second hot water supply circuit of a water heater, by cut-off of a flow path in a first hot water supply circuit of a space-heating water heater by a cut-off mechanism. When a load imposed by hot water supply by the second hot water supply circuit increases during the hot water supply operation in the single mode, the cut-off mechanism is opened to start hot water output from the first hot water supply circuit and a hot water supply operation in a parallel mode is performed in which hot water is output from both of the first hot water supply circuit and the second hot water supply circuit.

Abstract: A heating and hot water supplying device includes: a circulation passage that connects a heat exchanger and an external heating terminal; a bypass passage that bypasses the heating terminal by branching from the circulation passage; a hot water supply passage for supplying the hot water heated to a preset hot water supply temperature by the heat exchanger for hot water supply; a control unit that controls operations in which this plurality of units are used; and an operation terminal for performing various operations. A distribution valve is provided in the branching portion of the bypass passage. The distribution valve adjusts the distribution ratio so that each of a heating operation, a hot water supplying operation, and a simultaneous heating and hot water supplying operation is possible. The operation terminal is provided with a prohibit switch to prohibit the simultaneous heating and hot water supplying operation.

Abstract: In a heating and hot water supply device including a burning means, a first heat exchanger, a circulation passage for circulating a heating thermal medium, a circulation pump, a first bypass passage, a second heat exchanger for hot water supply, a hot water supply passage, a distribution means at a branching portion of the first bypass passage, and a second bypass passage bypassing the second heat exchanger, a flow rate adjustment means for adjusting a bypass flow rate in the second bypass passage is provided. The distribution means is capable of adjusting its distribution ratio for heating, or hot water supply, or simultaneous heating/hot water supply. All passage connection portions on the second heat exchanger were provided on its one side portion.

Abstract: A heating and hot-water-supply apparatus is provided with: a control unit that performs control on the basis of detection parameters of a plurality of detection means installed at the aforementioned locations and a setting parameter set in an operation unit. The distribution means can adjust the distribution ratio so as to correspond to a heating operation, a hot-water supply operation, and the simultaneous heating and hot-water-supply operation. The control unit prohibits the simultaneous heating and hot-water-supply operation in a case in which the required heating capacity for the hot-water supply operation calculated on the basis of the detection parameters and the setting parameter is equal to or greater than a predetermined standard capacity.

Abstract: In a heating and hot water supply device including a burning means, a first heat exchanger, a circulation passage for circulating a heating thermal medium, a circulation pump, a first bypass passage, a second heat exchanger for hot water supply, a hot water supply passage, a second bypass passage bypassing the second heat exchanger, a control unit, and an operating terminal, a distribution means is provided at a branching portion of the first bypass passage and is capable of adjusting its distribution ratio for heating, or hot water supply, or simultaneous heating/hot water supply, a display means of the operating terminal is capable of providing displays corresponding to various types of operation.

Abstract: A heating and hot water supplying device is provided. The device comprising: a circulation passage that connects a heat exchanger and an external heating terminal; a bypass passage that bypasses the heating terminal by branching from the circulation passage; a hot water supply passage for supplying the hot water heated to a preset hot water supply temperature by the heat exchanger for hot water supply; a control unit that controls operations in which this plurality of units are used; and an operation unit for performing various operations. A distribution means is provided in the branching portion of the bypass passage. The distribution means adjusts the distribution ratio so that each of a heating operation, a hot water supplying operation, and a simultaneous heating and hot water supplying operation is possible. The operation unit is provided with a prohibit switch to prohibit the simultaneous heating and hot water supplying operation.

Abstract: In a heating and hot water supply device comprising a burning means, a first heat exchanger, a circulation passage for circulating a heating thermal medium, a circulation pump, a first bypass passage, a second heat exchanger for hot water supply, a hot water supply passage, a second bypass passage bypassing the second heat exchanger, and a control unit, a distribution means is provided at a first branching portion of the first bypass passage and is capable of adjusting its distribution ratio for heating, or hot water supply, or simultaneous heating/hot water supply, during heating operation, the hot water supply passage is closed by a flow rate adjustment means provided in the hot water supply passage.

Abstract: In a heating and hot water supply device including a burning means, a first heat exchanger, a circulation passage for circulating a heating thermal medium, a circulation pump, a first bypass passage, a second heat exchanger for hot water supply, a hot water supply passage, a second bypass passage bypassing the second heat exchanger, a control unit, and an operating terminal, a distribution means is provided at a branching portion of the first bypass passage and is capable of adjusting its distribution ratio for heating, or hot water supply, or simulataneous heating/hot water supply, a display means of the operating terminal is capable of providing dispalys corresponding to various types of operation.

Abstract: In a heating and hot water supply device including a burning means, a first heat exchanger, a circulation passage for circulating a heating thermal medium, a circulation pump, a first bypass passage, a second heat exchanger for hot water supply, a hot water supply passage, a distribution means at a branching portion of the first bypass passage, and a second bypass passage bypassing the second heat exchanger, a flow rate adjustment means for adjusting a bypass flow rate in the second bypass passage is provided. The distribution means is capable of adjusting its distribution ratio for heating, or hot water supply, or simulataneous heating/hot water supply. All passage connection portions on the second heat exchanger were provided on its one side portion.

Abstract: When a hot water supply operation is started, a single mode is used in which hot water is output only from a second hot water supply circuit of a water heater, by cut-off of a flow path in a first hot water supply circuit of a space-heating water heater by a cut-off mechanism. When a load imposed by hot water supply by the second hot water supply circuit increases during the hot water supply operation in the single mode, the cut-off mechanism is opened to start hot water output from the first hot water supply circuit and a hot water supply operation in a parallel mode is performed in which hot water is output from both of the first hot water supply circuit and the second hot water supply circuit.

Abstract: A heating device with hot water supply function includes: a combustion means; a first heat exchanger; a circulation passage that connects the first heat exchanger and an room heating unit; a circulation pump; a bypass passage that branches off from the circulation passage; a second heat exchanger for hot water supply provided in the bypass passage; a cold water supply passage; a hot water supply passage for supply of hot water from the second heat exchanger; and a distribution means that is provided at a branching section and whose distribution ratio can be adjusted, so that it becomes possible selectively to execute either only room heating operation, or only hot water supply operation, or simultaneous room heating operation and hot water supply operation; wherein the hot water supply outlet, the thermal medium inlet, and the room heating outlet of the distribution means are at the same height.

Abstract: A heating device with hot water supply function includes: a combustion means; a main heat exchanger; a circulation passage connecting the main heat exchanger to an heating apparatus; a circulation pump provided in the circulation passage; a bypass passage that branches off from the circulation passage and bypasses the room heating apparatus; a secondary heat exchanger provided in the bypass passage; a cold water supply passage for supplying cold water to the secondary heat exchanger; a hot water supply passage for supplying hot water heated by the secondary heat exchanger; a hot water supply bypass passage that connects the cold water supply passage to the hot water supply passage bypassing the secondary heat exchanger; a flow adjustment means for adjusting the flow rate in the hot water supply bypass passage and thereby controlling the temperature of hot water to be supplied; and an expanded passage portion of the hot water supply passage whose diameter is increased from an intermediate portion of the hot wa

Abstract: The present invention relates to materials and methods for the identification of agents that regulate glycine transport in or out of cells, particularly in or out of neuronal and neuronal-associated cells. Such materials include non-mammalian cells having transfected therein a glycine transporter. The methods relate to the manipulation of such cells such that agents are identified that cause intake or outflow of glycine with respect to a given glycine transporter.

Abstract: The present invention relates to materials and methods for the identification of agents that regulate glycine transport in or out of cells, particularly in or out of neuronal and neuronal-associated cells. Such materials include non-mammalian cells having transfected therein a glycine transporter. The methods relate to the manipulation of such cells such that agents are identified that cause intake or outflow of glycine with respect to a given glycine transporter.

Abstract: A hybrid plasminogen activator-like polypeptide comprising a polypeptide region responsible for an affinity to fibrin derived from a tissue plasminogen activator polypeptide and a polypeptide region responsible for an enzyme activity derived from a prourokinase polypeptide; a DNA segment coding for the hybrid polypeptide; plasmid containing the DNA segment; a microorganism transformed with the DNA; and a process for production of the hybrid polypeptide comprising culturing the microorganism and recovering the hybrid polypeptide from the cultured cells.