Patents by Inventor Mieko Kogi

Mieko Kogi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for collecting nucleated red blood cells via density-gradient centrifugation utilizing changes in blood cell density
    Patent number: 9334477
    Abstract: Method for concentrating and collecting small quantities of fetal nucleated red blood cells contained in the maternal blood. The method for concentrating and collecting nucleated red blood cells from the maternal blood comprises: (i) subjecting the maternal blood to a first density-gradient centrifugation and collecting a cell fraction containing nucleated red blood cells; (ii) treating the cell fraction containing nucleated red blood cells so as to selectively changes the density of the nucleated red blood cells from that of the white blood cells; and (iii) subjecting the treated cell fraction containing the nucleated red blood cells to a second density-gradient centrifugation so as to collect a fraction containing nucleated red blood cells.
    Type: Grant
    Filed: February 21, 2011
    Date of Patent: May 10, 2016
    Assignees: JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY, KANAZAWA INSTITUTE OF TECHNOLOGY, KANAZAWA MEDICAL UNIVERSITY
    Inventors: Yuzuru Takamura, Kotaro Idegami, Mieko Kogi, Haruo Takabayashi
  • METHOD FOR COLLECTING NUCLEATED RED BLOOD CELLS VIA DENSITY-GRADIENT CENTRIFUGATION UTILIZING CHANGES IN BLOOD CELL DENSITY
    Publication number: 20130072402
    Abstract: This invention provides a method for concentrating and collecting small quantities of fetal nucleated red blood cells contained in the maternal blood. The method for concentrating and collecting nucleated red blood cells from the maternal blood comprises: (i) subjecting the maternal blood to a first density-gradient centrifugation and collecting a cell fraction containing nucleated red blood cells; (ii) treating the cell fraction containing nucleated red blood cells so as to selectively changes the density of the nucleated red blood cells from that of the white blood cells; and (iii) subjecting the treated cell fraction containing the nucleated red blood cells to a second density-gradient centrifugation so as to collect a fraction containing nucleated red blood cells.
    Type: Application
    Filed: February 21, 2011
    Publication date: March 21, 2013
    Applicants: JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY, KANAZAWA MEDICAL UNIVERSITY, KANAZAWA INSTITUTE OF TECHNOLOGY
    Inventors: Yuzuru Takamura, Kotaro Idegami, Mieko Kogi, Haruo Takabayashi