Abstract: The present invention relates to a novel fused ring compound having urea structure that exhibits excellent NAMPT activating effect, and a method using the same for treating/preventing metabolic disorder, cardiovascular and kidney disease, mitochondrial disease, neurodegenerative disease, ocular disease, and muscle wasting disorder. The present invention provides a compound represented by following formula (I) or a pharmacologically acceptable salt: Formula (I) wherein A, B, R, R2 and R3 represent the same meanings as in the claims.

Abstract: An object of the present invention is to provide a compound useful as a therapeutic drug for an autoimmune disease such as systemic lupus erythematosus (SLE) and lupus nephritis of SLE patients by suppressing immune cell function by inhibiting proliferation of activated T cells and production of interferon alpha (IFN-?). The present invention provides a compound represented by formula (I): wherein R1, R2 and R3 are the same as defined in the specification, or a pharmaceutically acceptable salt thereof.

Abstract: The present invention relates to a novel fused ring compound having urea structure that exhibits excellent NAMPT activating effect, and a method using the same for treating/preventing metabolic disorder, cardiovascular and kidney disease, mitochondrial disease, neurodegenerative disease, ocular disease, and muscle wasting disorder. The present invention provides a compound represented by following formula (I) or a pharmacologically acceptable salt: Formula (I) wherein A, B, R, R2 and R3 represent the same meanings as in the claims.

Abstract: A manufacturing method of a vacuum multilayer glass includes assembling an assembly including a first glass plate, a second glass plate, a sealing material and a getter material; carrying a conveyance table for conveying the assembly into a heating furnace; and heating the assembly in a reduced pressure space in the heating furnace to melt the sealing material and to activate the getter material at the same time, then solidifying the sealing material to bond the first glass plate and the second glass plate with the sealing material and to seal the reduced pressure space formed between the first glass plate and the second glass plate in a state of including the getter material, and causing the getter material to absorb gasses inside the reduced pressure space.

Abstract: A vacuum insulating glazing includes first and second glass substrates that are stacked with a gap set at a pressure less than an atmospheric pressure, and the gap is sealed peripherally by a sealing. The sealing includes a metal component and a glass layer that bonds the metal component and the glass substrates. A material for the metal component is selected from materials whose tensile strength X (N/mm2) and breaking elongation Y (%) satisfy a relationship Y?0.10X by a room temperature tensile test (tensile speed: 1 mm/min) that is performed after the materials are kept at 490° C. for 40 minutes in an atmosphere.

Abstract: The present invention provides a method for smoothing an optical surface of an optical component for EUVL. Specifically, the present invention provides a method for smoothing an optical surface of an optical component for EUVL made of a silica glass material containing TiO2 and comprising SiO2 as a main component with a laser having an oscillation wavelength, to which the optical component for EUVL has an absorption coefficient of 0.01 ?m?1 or more, at a fluence of 0.3 to 1.5 J/cm2 in an atmosphere having a water vapor partial pressure of 3.6 mmHg or less.

Abstract: To provide a method for smoothing a surface of a glass substrate having a concave defect, such as a pit or a scratch. A method for smoothing a surface of a glass substrate having a concave defect thereon, comprising: forming a film on the surface of the glass substrate having the concave defect by a dry deposition method, the film comprising a glass material having a fluid point Tf of 150° C. or above and of not higher than a strain point Ts (° C.) of the glass substrate; and heating the film of the glass material at a temperature of not lower than Tf and not higher than Ts to put the film in such state that the film of the glass material can flow so as to bury the concave defect, followed by cooling the film of the glass material, thereby to smooth the surface of the glass substrate having the concave defect.

Abstract: The present invention provides a method for smoothing an optical surface of an optical component for EUVL. Specifically, the present invention provides a method for smoothing an optical surface of an optical component for EUVL made of a silica glass material containing TiO2 and comprising SiO2 as a main component with a laser having an oscillation wavelength, to which the optical component for EUVL has an absorption coefficient of 0.01 ?m?1 or more, at a fluence of 0.3 to 1.5 J/cm2 in an atmosphere having a water vapor partial pressure of 3.6 mmHg or less.

Abstract: An organic EL display device includes color filters 102, an overcoat layer 103 and an inorganic solid layer 104 disposed on a substrate 101; a first electrodes 105, an organic film 107 and a second electrodes 108 disposed on the inorganic solid layer 104; an insulating layer 106 disposed so as to cover edge portions of the first electrodes. The organic EL display device can improve production yield and restrain visual failure from being caused with the lapse of time by including a protection layer 109 so as to prevent the inorganic solid layer 104 from being damaged.

Abstract: To provide a method for smoothing a surface of a glass substrate having a concave defect, such as a pit or a scratch. A method for smoothing a surface of a glass substrate having a concave defect thereon, comprising: forming a film on the surface of the glass substrate having the concave defect by a dry deposition method, the film comprising a glass material having a fluid point Tf of 150° C. or above and of not higher than a strain point Ts (° C.) of the glass substrate; and heating the film of the glass material at a temperature of not lower than Tf and not higher than Ts to put the film in such state that the film of the glass material can flow so as to bury the concave defect, followed by cooling the film of the glass material, thereby to smooth the surface of the glass substrate having the concave defect.

Abstract: An organic EL display device includes color filters 102, an overcoat layer 103 and an inorganic solid layer 104 disposed on a substrate 101; a first electrodes 105, an organic film 107 and a second electrodes 108 disposed on the inorganic solid layer 104; an insulating layer 106 disposed so as to cover edge portions of the first electrodes. The organic EL display device can improve production yield and restrain visual failure from being caused with the lapse of time by including a protection layer 109 so as to prevent the inorganic solid layer 104 from being damaged.

Abstract: A transparent coated molded product comprising a transparent synthetic resin substrate and two or more transparent cured material layers provided on at least one part of the surface of the transparent synthetic resin substrate, wherein an inner layer in contact with the outermost layer of the two or more transparent cured material layers is an abrasion-resistant layer which is a cured material of an active energy ray-curable coating agent (A) containing a polyfunctional compounds (a) having at least 2 active energy ray-curable polymerizable functional groups and the outermost layer is a silica layer which is a cured material of a curable coating agent (B) of polysilazane or a curable coating agent (B) containing polysilazane.