Patents by Inventor Mikael Berg
Mikael Berg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11960536Abstract: A method, device and system for organizing media content on a computer-based system to form a playlist, wherein the device has access to a database with a plurality of music tracks and associated feature vectors including feature values representing different semantic characteristics of a music track, as well as metadata including at least one type of metadata record representing associated information about the respective music track. The playlist is determined based on a query from the client device that includes an input vector, and at least one input metadata record, using an additional similarity matrix representing a measure of similarity between different metadata records of the same type.Type: GrantFiled: September 30, 2020Date of Patent: April 16, 2024Assignee: Moodagent A/SInventors: Mikael Henderson, Peter Berg Steffensen, David Stubbe Teglbjærg, Jesper Steen Andersen, Jose Luis Diez Antich, Thomas Jørgensen
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Publication number: 20220204555Abstract: The present invention relates to a method for purification of plasma proteins. More closely, the invention relates to a method using magnetic beads for separation of different plasma proteins from a plasma fraction, such as a cryoprecipitate or cryosupernatant of plasma, or alternatively directly from cell culture of recombinant plasma proteins.Type: ApplicationFiled: May 11, 2020Publication date: June 30, 2022Inventors: Martin HALL, Mats ANDER, Mikael BERG, Sandeep KRISTIANSSON
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Patent number: 11352388Abstract: The present invention relates to the field of chromatography. More closely, the invention relates to a chromatographic method for purification of Factor VIII and von Willebrand factor from a cryoprecipitate of plasma. The chromatographic method is performed on a matrix comprising an inner porous core and outer porous lid surrounding said core.Type: GrantFiled: April 4, 2016Date of Patent: June 7, 2022Assignee: Cytiva BioProcess R&D ABInventors: Martin Hall, Mikael Berg, Ida Eklind, Sandeep Kristiansson
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Publication number: 20210269888Abstract: The present invention relates to a method for optimizing a bioprocess purification system comprising a bioreactor configured to provide a harvest comprising a target composition, and a purification process arranged downstream the bioreactor and being configured for purification of the harvest to produce a target product having a desired characteristics. The method comprising: a) detecting (32) at least one quality attribute indicative of characteristics of the target product in a downstream process, b) identifying (33) correlations between the at least one quality attribute measured in the downstream process and parameters to control a cell culture process in the bioreactor, and c) controlling (34) the cell culture process to meet the desired characteristics based on the identified correlations, whereby the target characteristics is within a pre-determined range.Type: ApplicationFiled: July 1, 2019Publication date: September 2, 2021Inventors: Key Hyckenberg, Helena Skoglar, Gunnar Malmquist, Mikael Carlsten, Roger Lundqvist, Dan Andersson, Linda Mathiasson, Lars Mattsson, Sara Sendabo, Mikael Berg
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Patent number: 10955092Abstract: There is provided a method of preparing a mixed liquid having a first property and a second property. The method includes providing a first set of liquids, a second set of liquids, and a third set of liquids. The method includes combining the provided sets of liquids. Further, the method includes varying at least one of the liquid flows of the first and second sets and at least one liquid flow of the third set to adjust the first property and the second property to their respective predetermined values in the resulting mixed liquid flow.Type: GrantFiled: May 5, 2011Date of Patent: March 23, 2021Assignee: Cytiva Sweden ABInventors: Catalin Andrei, Mikael Berg, Torbjorn Blank, Enrique Carredano, Karl Ekstrom, Tomas M. Karlsson, Jan-Erik Lynga, Roger Nordberg, Gustav Rodrigo, Henrik Sandegren
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Patent number: 10704111Abstract: A method for manufacturing of steel articles comprises nitriding (210) a steel article at a nitrification temperature in the interval 350-650° C., giving a nitrided steel article. The nitrided steel article is quenched (220) in a reactive quenching oil from the nitrification temperature. The reactive quenching oil comprises at least one of S, P, B, Mo and W. Thereby, the quenching additionally comprises coating (222) of the nitrided steel article by a solid lubricant comprising at least one of S, P, B, Mo and W. An apparatus for manufacturing of steel articles, a quenching oil and a steel article produced by the method are also disclosed.Type: GrantFiled: October 25, 2016Date of Patent: July 7, 2020Assignees: APPLIED NANO SURFACES SWEDEN AB, BODYCOTE VÄRMEBEHANDLING ABInventors: Mikael Berg, Mikael Fällström, Boris Zhmud
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Patent number: 10598638Abstract: A chromatography lab system comprising a cooling compartment arranged to hold both fraction collector devices and sample containers, whereby the cooling compartment comprises an identifying device which is arranged to identify the fraction collector devices such that fractions from the chromatography are collected only in the fraction collector devices.Type: GrantFiled: October 30, 2018Date of Patent: March 24, 2020Assignee: GE Healthcare Bio-Sciences ABInventors: Bjorn Olovsson, Karol Lacki, Mikael Berg
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Publication number: 20200054964Abstract: The present invention relates to a method for determining operational status of a chromatography column (1; 39, 47, 59; 107, 109, 111, 113), comprising detecting a feed signal (21; 201) representative of the composition of a feed material provided to the inlet of the column; detecting the UV absorbance in the feed material, detecting an effluent signal (23; 203, 205, 207, 209) representative of the composition of the effluent from the column; and using the feed signal and the effluent signal to determine operational status of the column. The feed signal is generated using a first UV detector having a first UV cell pathlength operating at a first UV wavelength and in the effluent signal is generated using a second UV detector having a second UV cell pathlength operating at a second UV wavelength.Type: ApplicationFiled: February 14, 2018Publication date: February 20, 2020Inventors: Hans Blom, Mikael Berg, Hanno Ehring, Linda Mathiasson, Helena Skoglar, Rebecka Chmielowski
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Publication number: 20190153556Abstract: A method for manufacturing of steel articles comprises nitriding (210) a steel article at a nitrification temperature in the interval 350-650° C., giving a nitrided steel article. The nitrided steel article is quenched (220) in a reactive quenching oil from the nitrification temperature. The reactive quenching oil comprises at least one of S, P, B, Mo and W. Thereby, the quenching additionally comprises coating (222) of the nitrided steel article by a solid lubricant comprising at least one of S, P, B, Mo and W. An apparatus for manufacturing of steel articles, a quenching oil and a steel article produced by the method are also disclosed.Type: ApplicationFiled: October 25, 2016Publication date: May 23, 2019Applicants: APPLIED NANO SURFACES SWEDEN AB, BODYCOTE VÄRMEBEHANDLING ABInventors: Mikael BERG, Mikael FÄLLSTRÖM, Boris ZHMUD
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Publication number: 20190128859Abstract: A chromatography lab system comprising a cooling compartment arranged to hold both fraction collector devices and sample containers, whereby the cooling compartment comprises an identifying device which is arranged to identify the fraction collector devices such that fractions from the chromatography are collected only in the fraction collector devices.Type: ApplicationFiled: October 30, 2018Publication date: May 2, 2019Applicant: GE Healthcare Bio-Sciences ABInventors: Bjorn Olovsson, Karol Lacki, Mikael Berg
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Publication number: 20180127459Abstract: The present invention relates to the field of chromatography. More closely, the invention relates to a chromatographic method for purification of Factor VIII and von Willebrand factor from a cryoprecipitate of plasma. The chromatographic method is performed on a matrix comprising an inner porous core and outer porous lid surrounding said core.Type: ApplicationFiled: April 4, 2016Publication date: May 10, 2018Applicant: GE HEALTHCARE BIOPROCESS R&D ABInventors: Martin Hall, Mikael Berg, Ida Eklind, Sandeep Kristiansson
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Patent number: 9624262Abstract: There is a recognized need for novel, more simplified, approaches to isolation of plasma from whole blood, as well as a need to isolate cell-free plasma fractions containing different plasma proteins. Methods are divulged for use of aqueous phase systems, formed in blood or blood containing solutions via addition of a single polymer at relatively low concentration, to effect isolation (clarification) of plasma proteins from blood cells. Methods are also divulged to replace widely used Cohn-type plasma protein fractionation which is based on sequential addition of up to 40% (v/v) ethanol and other precipitants, with simple sequential addition of a polyacid. The latter results in isolation of plasma protein fractions (i.e. fibrinogen, immunoglobulin, albumin) in sequence similar to that obtained with Cohn Fractionation and therefore may be suitable for use to reduce solvent use and solvent-related process complications in existing plasma protein purification processes.Type: GrantFiled: September 14, 2012Date of Patent: April 18, 2017Assignee: GE Healthcare BioProcess R&D ABInventors: James Van Alstine, Mikael Berg, Johanna Kjorning, Jamil Shanagar
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Publication number: 20140343253Abstract: There is a recognized need for novel, more simplified, approaches to isolation of plasma from whole blood, as well as a need to isolate cell-free plasma fractions containing different plasma proteins. Methods are divulged for use of aqueous phase systems, formed in blood or blood containing solutions via addition of a single polymer at relatively low concentration, to effect isolation (clarification) of plasma proteins from blood cells. Methods are also divulged to replace widely used Cohn-type plasma protein fractionation which is based on sequential addition of up to 40% (v/v) ethanol and other precipitants, with simple sequential addition of a polyacid. The latter results in isolation of plasma protein fractions (i.e. fibrinogen, immunoglobulin, albumin) in sequence similar to that obtained with Cohn Fractionation and therefore may be suitable for use to reduce solvent use and solvent-related process complications in existing plasma protein purification processes.Type: ApplicationFiled: September 14, 2012Publication date: November 20, 2014Applicant: GE HEALTHCARE BIO-SCIENCES ABInventors: James Van Alstine, Mikael Berg, Johanna Kjorning, JAMIL Shanagar
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Publication number: 20130081703Abstract: A method of preparing a mixed liquid flow having predetermined characteristics, including a predetermined value of a first property and a predetermined value of a second property, comprising the steps of: a) providing a first set of at least one liquid flow each having a different first value of the first property; b) providing a second set of at least one liquid flow each having a different second value of the first property; c) providing a third set of at least one liquid flow of solvent; d) combining the provided liquid flows; and e) varying at least one of the liquid flows of the first and second sets and at least one liquid flow of the third set to adjust the first property and the second property to their respective predetermined values in the resulting mixed liquid flow.Type: ApplicationFiled: May 5, 2011Publication date: April 4, 2013Applicant: GE HEALTHCARE BIO-SCIENCES ABInventors: Catalin Andrei, Mikael Berg, Torbjorn Blank, Enrique Carredano, Karl Ekstrom, Tomas M. Karlsson, Jan-Erik Lynga, Roger Nordberg, Gustav Rodrigo, Henrik Sandegren
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Publication number: 20120289680Abstract: The present invention relates to a chromatography ligand, which comprises Domain C from Staphylococcus protein A (SpA), or a functional fragment or variant thereof. The chromatography ligand presents an advantageous capability of withstanding harsh cleaning in place (CIP) conditions, and is capable of binding Fab fragments of antibodies. The ligand may be provided with a terminal coupling group, such as arginine or cysteine, to facilitate its coupling to an insoluble carrier such as beads or a membrane. The invention also relates to a process of using the ligand in isolation of antibodies, and to a purification protocol which may include washing steps and/or regeneration with alkali.Type: ApplicationFiled: July 27, 2012Publication date: November 15, 2012Applicant: GE HEALTHCARE BIO-SCIENCES ABInventors: MARTIN HALL, STURE LARSSON, ANDREAS MURANYI, GUSTAV RODRIGO, JINYU ZOU, PER-MIKAEL ÅBERG
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Publication number: 20090047734Abstract: The present invention relates to a method of separating nucleic acids from a liquid, which comprises providing a mobile phase comprising nucleic acids and a first salt, which forms lyotropic ions when dissolved; passing said mobile phase across a hydrophobic interaction chromatography (HIC) matrix to adsorb deoxyribonucleic acid(s); passing an eluent across said matrix to desorb one or more deoxyribonucleic acid(s), which eluent comprises the first salt as well as an increasing gradient provided by a second salt, which second salt forms less lyotropic ions when dissolved than the first salt; and isolating at least one fraction comprising separated deoxyribonucleic acid(s).Type: ApplicationFiled: March 29, 2007Publication date: February 19, 2009Applicant: GE Healthcare Bio-Sciences ABInventors: Mikael Berg, Hans Blom, Raf Lemmens
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Patent number: 5627921Abstract: An optical fiber intended to be used as a sensor is of the kind suitable for communication and has a longitudinal cavity or hole which can be intentionally closed or has a more narrow shape at definite positions in the longitudinal direction of the fiber. The cavity, the diameter of which can be of the magnitude of order of 5 .mu.m-50 .mu.m, is filled with a material changing its volume depending on physical quantities in the fiber environment. The hole can be closed or made narrower at different positions in the longitudinal direction of the fiber for instance by locally heating the fiber by a pulsed laser beam.Type: GrantFiled: October 14, 1994Date of Patent: May 6, 1997Assignee: Telefonaktiebolaget LM EricssonInventors: Anne I. B. Lidgard, Leif G. Stensland, K. A. Mikael berg