Abstract: A method for segmentation of an image interactively with a user utilizes level set segmentation and includes selecting by user input respective areas of object and of background; initializing an embedding function implementing a segmentation boundary according to the selecting; computing intensity distributions and for the respective areas of object and of background; and performing repeatedly the steps below until convergence is reached: (a) evolving the embedding function, (b) recomputing the intensity distributions, and (c) checking for new user input and, if so: (d) updating labeling of the areas of object and background.

Abstract: A method for histogram calculation using a graphics processing unit (GPU), comprises storing image data in a two-dimensional (2D) texture domain; subdividing the domain into independent regions or tiles; calculating in parallel, in a GPU, a plurality of tile histograms, one for each tile; and summing up in parallel, in the GPU, the tile histograms so as to derive a final image histogram.

Abstract: A system and method for non-rigid image registration using distance functions includes portions for receiving a source shape into an image space, integrating a global linear registration model with local deformations to assess the source shape, optimizing a functional defined on a parameter or feature space where the functional quantifies the similarity between the source shape and a target shape in terms of distance functions, creating an augmented registration space including a plurality of target shape clones coherently positioned in the image space, tracking moving interfaces between the source shape and the target shapes and clones through a level set method, and registering the source shape by seeking mutual correspondences between the source shape, the target shape and the target shape clones.

Abstract: This invention relates to shape priors for level set representations. An embodiment of the invention comprises a first stage and a second stage. In the first stage, a shape model can be built directly on level set space using a collection of samples. The shape model can be constructed using a variational framework to create a non-stationary pixel-wise model that accounts for shape variabilities. Then, in the second stage, the shape model can be used as basis to introduce the shape prior in an energetic form. In terms of level set representations, the shape prior aims at minimizing non-stationary distance between the evolving interface and the shape model. An embodiment according to the present invention can be integrated with an existing, data-driven variational method to perform image segmentation for physically corrupted and incomplete data.

Abstract: A Bayesian formulation for coupled surface evolutions in level set methods and application to the segmentation of the prostate and the bladder in CT images are disclosed. A Bayesian framework imposing a shape constraint on the prostate is also disclosed, while coupling its shape extraction with that of the bladder. Constraining the segmentation process improves the extraction of both organs' shapes.

Abstract: Methods and systems for image segmentation are disclosed.

Abstract: This invention relates to shape priors for level set representations. An embodiment of the invention comprises a first stage and a second stage. In the first stage, a shape model can be built directly on level set space using a collection of samples. The shape model can be constructed using a variational framework to create a non-stationary pixel-wise model that accounts for shape variabilities. Then, in the second stage, the shape model can be used as basis to introduce the shape prior in an energetic form. In terms of level set representations, the shape prior aims at minimizing non-stationary distance between the evolving interface and the shape model. An embodiment according to the present invention can be integrated with an existing, data-driven variational method to perform image segmentation for physically corrupted and incomplete data.

Abstract: This invention relates to the integration of visual information, anatomic constraints, prior shape knowledge, and level set representations for the segmentation of medical images. An embodiment according to the present invention comprises a level set variational framework that uses a bi-directional boundary flow, an intensity-based regional component that maximizes the a posteriori segmentation probability, a physiology-based module that constrains the solution space and a term that accounts for shape-driven consistency. All modules are expressed in an energetic form and the resulting objective function is optimized using a gradient descent method.

Abstract: This invention relates to shape priors for level set representations. An embodiment of the invention comprises a first stage and a second stage. In the first stage, a shape model can be built directly on level set space using a collection of samples. The shape model can be constructed using a variational framework to create a non-stationary pixel-wise model that accounts for shape variabilities. Then, in the second stage, the shape model can be used as basis to introduce the shape prior in an energetic form. In terms of level set representations, the shape prior aims at minimizing non-stationary distance between the evolving interface and the shape model. An embodiment according to the present invention can be integrated with an existing, data-driven variational method to perform image segmentation for physically corrupted and incomplete data.

Abstract: This invention relates to the integration of visual information, anatomic constraints, prior shape knowledge, and level set representations for the segmentation of medical images. An embodiment according to the present invention comprises a level set variational framework that uses a bi-directional boundary flow, an intensity-based regional component that maximizes the a posteriori segmentation probability, a physiology-based module that constrains the solution space and a term that accounts for shape-driven consistency. All modules are expressed in an energetic form and the resulting objective function is optimized using a gradient descent method.

Abstract: A system and method for non-rigid image registration using distance functions includes portions for receiving a source shape into an image space, integrating a global linear registration model with local deformations to assess the source shape, optimizing a functional defined on a parameter or feature space where the functional quantifies the similarity between the source shape and a target shape in terms of distance functions, creating an augmented registration space including a plurality of target shape clones coherently positioned in the image space, tracking moving interfaces between the source shape and the target shapes and clones through a level set method, and registering the source shape by seeking mutual correspondences between the source shape, the target shape and the target shape clones.