Patents by Inventor Mikhail I. Papisov

Mikhail I. Papisov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biodegradable polyacetal polymers and methods for their formation and use
    Patent number: 5958398
    Abstract: The present invention relates to biodegradable biocompatible polyacetals, methods for their preparation, and methods for treating mammals by administration of biodegradable biocompatible polyacetals. A method for forming the biodegradable biocompatible polyacetals combines a glycol-specific oxidizing agent with a polysaccharide to form an aldehyde intermediate which is combined with a reducing agent to form the biodegradable biocompatible polyacetal. The resultant biodegradable biocompatible polyacetals can be chemically modified to incorporate additional hydrophilic moieties. A method for treating mammals includes the administration of the biodegradable biocompatible polyacetal in which biologically active compounds or diagnostic labels can be disposed.
    Type: Grant
    Filed: December 7, 1998
    Date of Patent: September 28, 1999
    Assignee: The General Hospital Corporation
    Inventor: Mikhail I. Papisov
  • Biodegradable polyacetal polymers and methods for their formation and use
    Patent number: 5863990
    Abstract: The present invention relates to biodegradable biocompatible polyacetals, methods for their preparation, and methods for treating mammals by administration of biodegradable biocompatible polyacetals. A method for forming the biodegradable biocompatible polyacetals combines a glycol-specific oxidizing agent with a polysaccharide to form an aldehyde intermediate which is combined with a reducing agent to form the biodegradable biocompatible polyacetal. The resultant biodegradable biocompatible polyacetals can be chemically modified to incorporate additional hydrophilic moieties. A method for treating mammals includes the administration of the biodegradable biocompatible polyacetal in which biologically active compounds or diagnostic labels can be disposed.
    Type: Grant
    Filed: June 9, 1997
    Date of Patent: January 26, 1999
    Assignee: The General Hospital Corporation
    Inventor: Mikhail I. Papisov
  • Biodegradable polyacetal polymers and methods for their formation and use
    Patent number: 5811510
    Abstract: The present invention relates to biodegradable biocompatible polyacetals, methods for their preparation, and methods for treating mammals by administration of biodegradable biocompatible polyacetals. A method for forming the biodegradable biocompatible polyacetals combines a glycol-specific oxidizing agent with a polysaccharide to form an aldehyde intermediate which is combined with a reducing agent to form the biodegradable biocompatible polyacetal. The resultant biodegradable biocompatible polyacetals can be chemically modified to incorporate additional hydrophilic moieties. A method for treating mammals includes the administration of the biodegradable biocompatible polyacetal in which biologically active compounds or diagnostic labels can be disposed.
    Type: Grant
    Filed: April 14, 1995
    Date of Patent: September 22, 1998
    Assignee: General Hospital Corporation
    Inventor: Mikhail I. Papisov
  • System of drug delivery to the lymphatic tissues
    Patent number: 5582172
    Abstract: A substance for diagnosis or therapy of an animal. The substance includes an agent which is detectable or therapeutically active, the agent being linked to a carrier which is linked to a targeting site, whereby the agent accumulates in the lymphatic system of the animal to a greater degree than if the targeting site were absent.
    Type: Grant
    Filed: January 18, 1995
    Date of Patent: December 10, 1996
    Assignee: The General Hospital Corporation
    Inventors: Mikhail I. Papisov, Thomas J. Brady