Patents by Inventor Miklos Ghyczy

Miklos Ghyczy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160326098
    Abstract: The present application refers to a medicinally active compound of formula (I) and its possible use as anti-inflammatory agent. Further, the present application refers to a method for the preparation of the compound of formula (I) as well as to a pharmaceutical composition comprising a compound of formula (I).
    Type: Application
    Filed: December 17, 2014
    Publication date: November 10, 2016
    Applicant: Pax Forschung GmbH
    Inventor: Miklos Ghyczy
  • Patent number: 7192597
    Abstract: A composition, especially for treatment of aged and/or stressed skin, the composition containing, in addition to water, at least one substance that forms lamellar structures with water. The composition further contains S-adenosylmethionine and/or at least one compound that contains a functional group of the general formula —CH2—N?—(CH3)3. The lamellar structure has a layer structure in which an upper layer of the substance is aligned with a lower layer, the hydrophilic groups of the substance each point outwards, and the lipophilic groups of the substance are aligned inwards with one another. The lamellar structure is surrounded by a hydrophilic medium, preferably water.
    Type: Grant
    Filed: May 24, 2005
    Date of Patent: March 20, 2007
    Assignee: Kuhs GmbH
    Inventors: Martin Albrecht, Miklos Ghyczy
  • Patent number: 7001604
    Abstract: A cosmetic composition, especially for use on aged and/or stressed skin is described, whereby apart from water at least one substance forming lamellar structures with water is present in the composition. The composition further contains a) at least one compound which has at least one functional group of the general formula I —CH2—N?—(CH3)3??(formula I) b) and/or at least one metabolite of this compound, c) and/or S-adenosylmethionine.
    Type: Grant
    Filed: February 19, 2001
    Date of Patent: February 21, 2006
    Assignee: Kubs Kosmetik GmbH & Co. KG
    Inventors: Martin Albrecht, Miklos Ghyczy
  • Publication number: 20050208012
    Abstract: A composition, especially for treatment of aged and/or stressed skin, the composition containing, in addition to water, at least one substance that forms lamellar structures with water. The composition further contains S-adenosylmethionine and/or at least one compound that contains a functional group of the general formula —CH2—N?—(CH3)3. The lamellar structure has a layer structure in which an upper layer of the substance is aligned with a lower layer, the hydrophilic groups of the substance each point outwards, and the lipophilic groups of the substance are aligned inwards with one another. The lamellar structure is surrounded by a hydrophilic medium, preferably water.
    Type: Application
    Filed: May 24, 2005
    Publication date: September 22, 2005
    Inventors: Martin Albrecht, Miklos Ghyczy
  • Publication number: 20040235783
    Abstract: The present invention relates to a pharmaceutical composition comprising at least one active compound having cytostatic activity, at least one biological electron acceptor and customary pharmaceutical additives, and to its use for the treatment of tumor diseases, in particular for the treatment of cancer.
    Type: Application
    Filed: June 29, 2004
    Publication date: November 25, 2004
    Inventors: Miklos Ghyczy, Jorg Hager, Armin Wendel
  • Publication number: 20010021704
    Abstract: The present invention relates to a pharmaceutical composition comprising at least one active compound having cytostatic activity, at least one biological electron acceptor and customary pharmaceutical additives, and to its use for the treatment of tumor diseases, in particular for the treatment of cancer.
    Type: Application
    Filed: December 8, 2000
    Publication date: September 13, 2001
    Inventors: Miklos Ghyczy, Jorg Hager, Armin Wendel
  • Publication number: 20010016663
    Abstract: A method for the stabilization of a phospholipidic composition as well as a method for the production of a stabilized phospholipidic composition comprising at least one phospholipide as well as a stabilizer are described, whereby in the claimed methods at least one phospholipide is mixed with a stabilizer on the basis of phytic acid, of a salt of the phytic acid and/or of a phytic acid derivative.
    Type: Application
    Filed: May 22, 2000
    Publication date: August 23, 2001
    Applicant: RHONE-POULENC RORER GMBH & CO.
    Inventor: Miklos Ghyczy
  • Patent number: 6278004
    Abstract: A method for the stabilization of a phospholipidic composition as well as a method for the production of a stabilized phospholipidic composition comprising at least one phospholipide as well as a stabilizer are described, whereby in the claimed methods at least one phospholipide is mixed with a stabilizer on the basis of phytic acid, of a salt of the phytic acid and/or of a phytic acid derivative.
    Type: Grant
    Filed: May 22, 2000
    Date of Patent: August 21, 2001
    Assignee: Aventis Pharma Deutschland GmbH
    Inventor: Miklos Ghyczy
  • Patent number: 6126941
    Abstract: A phospholipidic composition provides resistance against rancidity and the development of undesirable odors. The composition includes at least one phospholipid and a stabilizer. The stabilizer is ground parts and/or an extract of a grain. The composition is prepared by simple and reliable methods of production.
    Type: Grant
    Filed: October 21, 1997
    Date of Patent: October 3, 2000
    Assignee: Rhone-Poulenc Rorer GmbH & Co.
    Inventor: Miklos Ghyczy
  • Patent number: 6100413
    Abstract: A method for the stabilization of a phospholipidic composition as well as a method for the production of a stabilized phospholipidic composition comprising at least one phospholipide as well as a stabilizer are described, whereby in the claimed methods at least one phospholipide is mixed with a stabilizer on the basis of phytic acid, of a salt of the phytic acid and/or of a phytic acid derivative.
    Type: Grant
    Filed: October 21, 1997
    Date of Patent: August 8, 2000
    Assignee: Rhone-Poulenc Rorer GmbH & Co.
    Inventor: Miklos Ghyczy
  • Patent number: 5741513
    Abstract: An alcoholic, aqueous gel-like phospholipid composition is disclosed which contains, as alcohols, ethanol, 1-propanol or 2-propanol, which is characterized in that this composition is a liposomal gel composed of 15.00 to 30.00 parts by weight of a phospholipid concentrate, 14.00 to 20.00 parts by weight of alcohol and 50 to 71.00 parts by weight of an aqueous solution as the remainder. The use of this phospholipid composition for the preparation of liposomal solutions by dilution with a solution and topical preparations which contain these solutions are additionally disclosed.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: April 21, 1998
    Assignee: A. Natterman & Cie. GmbH
    Inventors: Miklos Ghyczy, Joachim Roding, Hans Lautenschlager, Walter Hameister, Jorg Hager
  • Patent number: 5711965
    Abstract: An alcoholic, aqueous gel-like phospholipid composition is disclosed which contains, as alcohols, ethanol, 1-propanol or 2-propanol, which is characterized in that this composition is a liposomal gel composed of 15.00 to 30.00 parts by weight of a phospholipid concentrate, 14.00 to 20.00 parts by weight of alcohol and 50 to 71.00 parts by weight of an aqueous solution as the remainder. The use of this phospholipid composition for the preparation of liposomal solutions by dilution with a solution and topical preparations which contain these solutions are additionally disclosed.
    Type: Grant
    Filed: February 21, 1996
    Date of Patent: January 27, 1998
    Assignee: A. Natterman & Cie. GmbH
    Inventors: Miklos Ghyczy, Joachim Roding, Hans Lautenschlager, Walter Hameister, Jorg Hager
  • Patent number: 5523429
    Abstract: A method of inhibiting oxidation of products containing unsaturated fatty acids and their derivatives comprises treating the unsaturated fatty acids and their derivatives with N-acylphosphatidylethanolamines. Preferred N-acylphosphatidylethanolamines are N-acetylphosphatidylethanolamine and N-oleoylphosphatidylethanolamine.
    Type: Grant
    Filed: February 25, 1994
    Date of Patent: June 4, 1996
    Assignee: Rhone-Poulenc Rorer-GmbH
    Inventor: Miklos Ghyczy
  • Patent number: 5129950
    Abstract: The invention is related to the use of certain water-soluble compounds known as such and having the FormulaR.sup.1 --CO--NH--R.sup.2for the modulation of membrane dependent metabolism processes within living cells, in particular with relation to transport phenomena and cell procedures which are induced or influenced by active agents supplied from outside the cell, products containing these substances for the above described uses and processes using these products.
    Type: Grant
    Filed: December 6, 1990
    Date of Patent: July 14, 1992
    Assignee: A Nattermann & Cie GmbH
    Inventors: Miklos Ghyczy, Jorg Hager
  • Patent number: 4874553
    Abstract: Liquid phospholipid-containing products in an aqueous medium which contains 5-80% by weight of phospholipids and 3-10% by weight of one or more compounds of the general formulaRO--A--NR.sub.1 R.sub.2 R.sub.3their preparation and their use, for example as additives for improving plant treatment agents.
    Type: Grant
    Filed: March 11, 1987
    Date of Patent: October 17, 1989
    Assignee: A. Nattermann & Cie. GmbH
    Inventors: Hager, Jorg, Miklos Ghyczy, Vincent Feyen, Paul Imberge, Ulrich Brandenburg, Peter Wilperath
  • Patent number: 4687766
    Abstract: Pharmaceutical preparation containing phospholipids for the therapeutic treatment of rheumatic diseases which contain in addition to the antiphlogistically acting oxicam derivatives of the general formula ##STR1## special 1,2-diacyl-glycero-3-phosphocholines wherein 75-86% by weight of the acyl radicals are unsaturated fatty acid radicals, and the preparation thereof.
    Type: Grant
    Filed: December 21, 1984
    Date of Patent: August 18, 1987
    Assignee: A. Natterman & Cie, GmbH
    Inventors: Armin Wendel, Sigurd Leyck, Helmut Wetzig, Jorg Hager, Manfred Durr, Miklos Ghyczy
  • Patent number: 4684632
    Abstract: Pharmaceutical formulations for the treatment of gastrointestinal disorders, which contain as the active component an effective gastrointestinal disorder alleviating amount of a 1,2-diacylglycero-3-phosphocholine in which 75-86% by weight of the acyl radicals are unsaturated fatty acid radicals having a chain length of 16, 18 or 20 carbon atoms. The mixtures of fatty acid radicals in the acyl groups in the 1- and 2-positions preferably have different compositions. The formulations can also contain other active compounds, in particular those which display injurious gastrointestinal side effects.
    Type: Grant
    Filed: December 21, 1984
    Date of Patent: August 4, 1987
    Assignee: A. Nattermann & CIE. GmbH
    Inventors: Volker Schulz, Sigurd Leyck, Manfred Durr, Miklos Ghyczy, Armin Wendel, Jorg Hager
  • Patent number: 4681617
    Abstract: Phospholipid concentrates from natural or synthetic phospholipids and physiologically acceptable organic solvents and further additives of the following composition:20-60 wght. % phospholipids0-23 wght. % glycerin5-62.5 wght. % organic solvent0-30 wght. % co-emulsifier0-35 wght. % dissolving intermediary0-15 wght. % water0-15 wght. % vegetable oil or neutral oilThe phospholipids are a mixture of phosphatidyl choline, phosphatidyl ethanol amine, N-acetyl phosphatidyl ethanol amine, and other phosphatides, the concentrates perferably containing a mixture of 10-50 wght. % phosphatidyl choline, 10-30 wght. % phosphatidyl diethanol amine, 10-30 wght. % N-acylphosphatidyl ethanol amine, and 3-10 wght. % other phosphatides, in relation to the total quantity of phospholipids. The phospholipid concentrates are particularly suitable as auxiliary agents in the production and application of spray mixtures containing plant protectants.
    Type: Grant
    Filed: July 17, 1985
    Date of Patent: July 21, 1987
    Assignee: A. Nattermann & Cie, GmbH
    Inventors: Miklos Ghyczy, Paul-Robert Imberge, Armin Wendel
  • Patent number: 4576626
    Abstract: New foliage fertilizers containing one or more macronutrients and/or one or more micronutrients as well as 10 to 50% by weight (referred to total nutrients) of one or more phospholipids.
    Type: Grant
    Filed: April 15, 1985
    Date of Patent: March 18, 1986
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Kurt H. Bauer, Miklos Ghyczy, Eugen Etschenberg, Heinrich Osthoff
  • Patent number: 4567161
    Abstract: Liquid, active substance formulations containing an active substance insoluble or poorly soluble in water, or a mixture, a phospholipid, a special co-emulsifier (glycerinester in which the 1 or 2 OH groups have been esterized with hydrocarbon atoms of 8-16, preferably 8-10, C atoms by means of fatty acids and the 3 or remaining OH group of the glycerin body has been etherized with polyethyleneglycol, specifically, with 6-30, preferably 6-15 ethyleneoxide units) and a liquid carrier, the molar ratio of phospholipid to co-emulsifier being from 1:1 to 1:4, and the formulations being such that when added to water they form a transparent liquid system in the form of a microemulsion, with a degree of fineness of 10-200 nm in the lipid phase.
    Type: Grant
    Filed: June 28, 1983
    Date of Patent: January 28, 1986
    Assignee: A. Natterman & Cie GmbH
    Inventors: Ulrich Posanski, Miklos Ghyczy, Kurt-Heinz Bauer, Armin Wendel